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API Impurities

(2R)-3-Acetylthio-2-methylpropionyl Chloride

Reference StandardAvailable on request

(2R)-3-Acetylthio-2-methylpropionyl Chloride (CAS 74345-73-6) supplier Zemixal: C6H9ClO2S, COA and SDS with every lot, worldwide shipping.

Pack sizes
(2R)-3-Acetylthio-2-methylpropionyl Chloride chemical structure
CAS number74345-73-6
FormulaC6H9ClO2S
Molar mass180.65 g/mol
Physical formSolid
HS code38229090
InChIKeyLUDPWTHDXSOXDX-SCSAIBSYSA-N
IUPAC nameS-[(2R)-3-chloro-2-methyl-3-oxopropyl] ethanethioate

About (2R)-3-Acetylthio-2-methylpropionyl Chloride

(2R)-3-Acetylthio-2-methylpropionyl Chloride belongs to the Captopril reference-standard family in the Zemixal catalogue. Key data (Reference Standard): CAS 74345-73-6, formula C6H9ClO2S and molar mass 180.65 g/mol. It is handled as a solid.

Use cases we see most often

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Safe handling

It carries the GHS signal word Danger (H290, H314 and H318), so wear gloves and eye protection and work with good ventilation.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and custom quantities are quoted on request. You receive a certificate of analysis with characterisation data with each order. Request pricing online and we confirm availability, documentation and freight to your country.

Reference standards for Captopril

See every impurity, metabolite and related compound we list for this API.

Captopril standards

Typical uses

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Applications

Specifications and identifiers

Specifications of (2R)-3-Acetylthio-2-methylpropionyl Chloride
Product name(2R)-3-Acetylthio-2-methylpropionyl Chloride
Catalogue numberZX-032869
CAS number74345-73-6
IUPAC nameS-[(2R)-3-chloro-2-methyl-3-oxopropyl] ethanethioate
Molecular formulaC6H9ClO2S
Molar mass180.65 g/mol
Exact mass180.0012
GradeReference Standard
Physical formSolid
XLogP31.7
H-bond donors / acceptors0 / 3
Topological polar surface area59.4 Ų
HS code38229090
InChIKeyLUDPWTHDXSOXDX-SCSAIBSYSA-N
SMILESC[C@H](CSC(=O)C)C(=O)Cl
PubChem CID11830043
Synonyms(R)-3-(Acetylthio)isobutyryl Chloride, (R)-S-(3-chloro-2-methyl-3-oxopropyl) ethanethioate, (R)-3-acetylthio-2-methylpropanoyl chloride

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS05 Corrosive
Corrosive

Signal word Danger

  • H290May be corrosive to metals
  • H314Causes severe skin burns and eye damage
  • H318Causes serious eye damage

Precautionary statements P234, P260, P264, P264 + P265, P280, P301 + P330 + P331, P302 + P361 + P354, P304 + P340, P305 + P354 + P338, P316, P317, P321, P363, P390, P405, P406, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of (2R)-3-Acetylthio-2-methylpropionyl Chloride
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about (2R)-3-Acetylthio-2-methylpropionyl Chloride

Which CAS number identifies (2R)-3-Acetylthio-2-methylpropionyl Chloride?
(2R)-3-Acetylthio-2-methylpropionyl Chloride is registered under CAS 74345-73-6. You may also see it listed as (R)-3-(Acetylthio)isobutyryl Chloride, (R)-S-(3-chloro-2-methyl-3-oxopropyl) ethanethioate, (R)-3-acetylthio-2-methylpropanoyl chloride. Our catalogue number for this item is ZX-032869.
What are the formula and molar mass of (2R)-3-Acetylthio-2-methylpropionyl Chloride?
For (2R)-3-Acetylthio-2-methylpropionyl Chloride, its formula is C6H9ClO2S and its molar mass is 180.65 g/mol. The systematic (IUPAC) name is S-[(2R)-3-chloro-2-methyl-3-oxopropyl] ethanethioate. InChIKey LUDPWTHDXSOXDX-SCSAIBSYSA-N lets you match it in any structure database.
How is (2R)-3-Acetylthio-2-methylpropionyl Chloride used in pharmaceutical QC?
(2R)-3-Acetylthio-2-methylpropionyl Chloride is a characterised reference material linked to Captopril. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for (2R)-3-Acetylthio-2-methylpropionyl Chloride?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with (2R)-3-Acetylthio-2-methylpropionyl Chloride?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship (2R)-3-Acetylthio-2-methylpropionyl Chloride to my country?
Yes. Because (2R)-3-Acetylthio-2-methylpropionyl Chloride is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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