Solvent quality decides whether a baseline is flat or a reaction runs dry, so the Solvents (HPLC & GC) division is organised by end use rather than by chemical family. You will find gradient-grade acetonitrile and methanol for liquid chromatography, residue-free hexane and dichloromethane for GC work, deuterated and spectroscopy grades, anhydrous solvents for moisture-sensitive synthesis, and industrial grades for extraction and cleaning.

Chromatography: HPLC, gradient and LC-MS grades with low UV cut-off and residue
Analysis: AR, ACS and spectroscopy grades for titration and UV-Vis
Synthesis: anhydrous and stabilised solvents for the reaction flask
Process: bulk and technical grades in drums and IBCs

Buyers usually decide on three numbers, which are water content, evaporation residue and UV absorbance at the method wavelength. Our COAs report these values for each lot. Flammable liquids are packed in UN-approved glass, metal or HDPE and travel as dangerous goods by sea from Nhava Sheva or Mundra, or by air where the class and quantity allow.

Solvents (HPLC & GC): questions buyers ask

Which solvent grade should I use for LC-MS rather than HPLC-UV?

LC-MS methods need solvents with very low metal ion and non-volatile residue content, because sodium and potassium adducts and background ions show up in the mass spectrum. HPLC-UV methods care mainly about UV cut-off and particle content. Choose LC-MS grade for mass detection and gradient HPLC grade for UV work to balance cost and performance.

How should opened bottles of HPLC solvent be stored?

Keep bottles tightly capped, away from light and at room temperature, and avoid topping up reservoirs with fresh solvent over old. Acetonitrile and methanol absorb moisture and pick up contaminants from the air, and tetrahydrofuran can form peroxides once its stabiliser is used up. Date each bottle on opening and follow your lab's in-use period.

Can I get one lot of solvent reserved for a long validation study?

Ask for this on your quotation. Where stock allows, we can supply the full quantity from a single lot so that retention times and blanks stay consistent across a validation campaign. The lot number appears on each container and on the COA, which makes traceability straightforward during audits.

Solvents (HPLC & GC) shipped to

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Have a list of compounds to price?

Paste up to 200 CAS numbers into Bulk CAS lookup, or send one enquiry for everything in your quote list. We reply with price, lead time and documents.

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