4-(Cyclopropylmethoxy)-3-(difluoromethoxy) Roflumilast
- CAS
- 162401-43-6
- Formula
- C17H14Cl2F2N2O3
- MW
- 403.2 g/mol
ZX-032272
Metabolites & Degradation Products
3-(Cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-hydroxybenzamide
Reference StandardAvailable on request
3-(Cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-hydroxybenzamide (CAS 475271-62-6) supplier Zemixal…
CAS number475271-62-6
FormulaC16H14Cl2N2O3
Molar mass353.2 g/mol
Physical formSolid
HS code38229090
InChIKeyIJTMJUHUWQHBEA-UHFFFAOYSA-N
IUPAC name3-(cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-hydroxybenzamide
About 3-(Cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-hydroxybenzamide
Zemixal lists 3-(Cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-hydroxybenzamide for laboratories that identify, quantify or control Roflumilast and its related substances. Key data (Reference Standard): CAS 475271-62-6, formula C16H14Cl2N2O3 and molar mass 353.2 g/mol. It is handled as a solid.
Typical applications
- Metabolite identification
- Stability-indicating methods
- Impurity profiling
Safe handling
Classified under GHS with signal word Warning and hazard statements H315, H319 and H335. Read the SDS before first use.
Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and custom quantities are quoted on request. Every shipment includes a certificate of analysis with characterisation data. Add it to your quote list and our team replies with price, lead time and shipping options within one business day.
Reference standards for Roflumilast
See every impurity, metabolite and related compound we list for this API.
Roflumilast standardsTypical uses
- Metabolite identification
- Stability-indicating methods
- Impurity profiling
Applications
Specifications and identifiers
| Product name | 3-(Cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-hydroxybenzamide |
|---|---|
| Catalogue number | ZX-032271 |
| CAS number | 475271-62-6 |
| IUPAC name | 3-(cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-hydroxybenzamide |
| Molecular formula | C16H14Cl2N2O3 |
| Molar mass | 353.2 g/mol |
| Exact mass | 352.0381 |
| Grade | Reference Standard |
| Physical form | Solid |
| XLogP3 | 3.3 |
| H-bond donors / acceptors | 2 / 4 |
| Topological polar surface area | 71.5 Ų |
| HS code | 38229090 |
| InChIKey | IJTMJUHUWQHBEA-UHFFFAOYSA-N |
| SMILES | C1CC1COC2=C(C=CC(=C2)C(=O)NC3=C(C=NC=C3Cl)Cl)O |
| PubChem CID | 66778561 |
| Synonyms | 4-O-Des(difluoromethyl) Roflumilast, Roflumilast-2, RofluMilast IMp.B, N-(3,5-dichloropyridin-4-yl)-4-hydroxybenzaMide, N-(3,5-dichloropyrid-4-yl)-3-cyclopropylmethoxy-4-hydroxybenzamide, 3-(cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridyl)-4-hydroxy-benzamide, Benzamide, 3-(cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-hydroxy- |
Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.
Safety and GHS hazards
Signal word Warning
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501
Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.
Pack sizes
| 10 mg | Quoted on request | |
| 25 mg | Quoted on request | |
| 50 mg | Quoted on request | |
| 100 mg | Quoted on request |
Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.
Questions about 3-(Cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-hydroxybenzamide
Which CAS number identifies 3-(Cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-hydroxybenzamide?
3-(Cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-hydroxybenzamide is registered under CAS 475271-62-6. You may also see it listed as 4-O-Des(difluoromethyl) Roflumilast, Roflumilast-2, RofluMilast IMp.B. Our catalogue number for this item is ZX-032271.
What are the formula and molar mass of 3-(Cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-hydroxybenzamide?
For 3-(Cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-hydroxybenzamide, its formula is C16H14Cl2N2O3 and its molar mass is 353.2 g/mol. The systematic (IUPAC) name is 3-(cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-hydroxybenzamide. InChIKey IJTMJUHUWQHBEA-UHFFFAOYSA-N lets you match it in any structure database.
How is 3-(Cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-hydroxybenzamide used in pharmaceutical QC?
3-(Cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-hydroxybenzamide is a characterised reference material linked to Roflumilast. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for 3-(Cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-hydroxybenzamide?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with 3-(Cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-hydroxybenzamide?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship 3-(Cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-hydroxybenzamide to my country?
Yes. Because 3-(Cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-hydroxybenzamide is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.
More Roflumilast standards
More in Metabolites & Degradation Products
3-(Cyclopropylmethoxy)-4-(difluoromethoxy)benzaldehyde
- CAS
- 151103-09-2
- Formula
- C12H12F2O3
- MW
- 242.22 g/mol
ZX-032277
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