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API Impurities

4,6-Dichloro-5-(4-chlorophenyl)pyrimidine

Reference StandardAvailable on request

4,6-Dichloro-5-(4-chlorophenyl)pyrimidine (CAS 3974-18-3) supplier Zemixal. Lab and bulk packs, batch COA, fast global delivery.

Pack sizes
4,6-Dichloro-5-(4-chlorophenyl)pyrimidine chemical structure
CAS number3974-18-3
FormulaC10H5Cl3N2
Molar mass259.5 g/mol
Physical formSolid
HS code38229090
InChIKeyKIYDKTUDEIWLNO-UHFFFAOYSA-N
IUPAC name4,6-dichloro-5-(4-chlorophenyl)pyrimidine

About 4,6-Dichloro-5-(4-chlorophenyl)pyrimidine

Zemixal lists 4,6-Dichloro-5-(4-chlorophenyl)pyrimidine for laboratories that identify, quantify or control Macitentan and its related substances. Identity at a glance (Reference Standard): CAS 3974-18-3, formula C10H5Cl3N2 and molar mass 259.5 g/mol. It is handled as a solid.

Where it is used

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Safe handling

Classified under GHS with signal word Warning and hazard statements H315, H317 and H319. Read the SDS before first use.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and custom quantities are quoted on request. Every shipment includes a certificate of analysis with characterisation data. Request pricing online and we confirm availability, documentation and freight to your country.

Reference standards for Macitentan

See every impurity, metabolite and related compound we list for this API.

Macitentan standards

Typical uses

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Applications

Specifications and identifiers

Specifications of 4,6-Dichloro-5-(4-chlorophenyl)pyrimidine
Product name4,6-Dichloro-5-(4-chlorophenyl)pyrimidine
Catalogue numberZX-030428
CAS number3974-18-3
IUPAC name4,6-dichloro-5-(4-chlorophenyl)pyrimidine
Molecular formulaC10H5Cl3N2
Molar mass259.5 g/mol
Exact mass257.9518
GradeReference Standard
Physical formSolid
XLogP34.4
H-bond donors / acceptors0 / 2
Topological polar surface area25.8 Ų
HS code38229090
InChIKeyKIYDKTUDEIWLNO-UHFFFAOYSA-N
SMILESC1=CC(=CC=C1C2=C(N=CN=C2Cl)Cl)Cl
PubChem CID21979569
SynonymsPyrimidine, 4,6-dichloro-5-(4-chlorophenyl)-, 5-(4-Chlorophenyl)-4,6-dichloropyrimidine

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS07 Irritant or harmful
Irritant or harmful

Signal word Warning

  • H315Causes skin irritation
  • H317May cause an allergic skin reaction
  • H319Causes serious eye irritation

Precautionary statements P261, P264, P264 + P265, P272, P280, P302 + P352, P305 + P351 + P338, P321, P332 + P317, P333 + P317, P337 + P317, P362 + P364, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of 4,6-Dichloro-5-(4-chlorophenyl)pyrimidine
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about 4,6-Dichloro-5-(4-chlorophenyl)pyrimidine

Which CAS number identifies 4,6-Dichloro-5-(4-chlorophenyl)pyrimidine?
4,6-Dichloro-5-(4-chlorophenyl)pyrimidine is registered under CAS 3974-18-3. You may also see it listed as Pyrimidine, 4,6-dichloro-5-(4-chlorophenyl)-, 5-(4-Chlorophenyl)-4,6-dichloropyrimidine. Our catalogue number for this item is ZX-030428.
What are the formula and molar mass of 4,6-Dichloro-5-(4-chlorophenyl)pyrimidine?
For 4,6-Dichloro-5-(4-chlorophenyl)pyrimidine, its formula is C10H5Cl3N2 and its molar mass is 259.5 g/mol. The systematic (IUPAC) name is 4,6-dichloro-5-(4-chlorophenyl)pyrimidine. InChIKey KIYDKTUDEIWLNO-UHFFFAOYSA-N lets you match it in any structure database.
How is 4,6-Dichloro-5-(4-chlorophenyl)pyrimidine used in pharmaceutical QC?
4,6-Dichloro-5-(4-chlorophenyl)pyrimidine is a characterised reference material linked to Macitentan. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for 4,6-Dichloro-5-(4-chlorophenyl)pyrimidine?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with 4,6-Dichloro-5-(4-chlorophenyl)pyrimidine?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship 4,6-Dichloro-5-(4-chlorophenyl)pyrimidine to my country?
Yes. Because 4,6-Dichloro-5-(4-chlorophenyl)pyrimidine is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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