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Metabolites & Degradation Products

4-Hydroxy Midazolam

Reference StandardAvailable on request

4-Hydroxy Midazolam (CAS 59468-85-8) supplier Zemixal. Request a quote with price, lead time and documents. Catalogue no. ZX-036833.

Pack sizes
4-Hydroxy Midazolam chemical structure
CAS number59468-85-8
FormulaC18H13ClFN3O
Molar mass341.8 g/mol
Physical formSolid
HS code38229090
InChIKeyZYISITHKPKHPKG-UHFFFAOYSA-N
IUPAC name8-chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepin-4-ol

About 4-Hydroxy Midazolam

Zemixal lists 4-Hydroxy Midazolam for laboratories that identify, quantify or control Midazolam and its related substances. Identity at a glance (Reference Standard): CAS 59468-85-8, formula C18H13ClFN3O and molar mass 341.8 g/mol. It is handled as a solid.

Use cases we see most often

  • Metabolite identification
  • Stability-indicating methods
  • Impurity profiling

Storage and safety notes

Classified under GHS with signal word Danger and hazard statements H301. Read the SDS before first use.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and custom quantities are quoted on request. Each lot travels with a certificate of analysis with characterisation data. Add it to your quote list and our team replies with price, lead time and shipping options within one business day.

Reference standards for Midazolam

See every impurity, metabolite and related compound we list for this API.

Midazolam standards

Typical uses

  • Metabolite identification
  • Stability-indicating methods
  • Impurity profiling

Applications

Pharmaceutical Manufacturing and QCResearch Labs and Universities

Specifications and identifiers

Specifications of 4-Hydroxy Midazolam
Product name4-Hydroxy Midazolam
Catalogue numberZX-036833
CAS number59468-85-8
IUPAC name8-chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepin-4-ol
Molecular formulaC18H13ClFN3O
Molar mass341.8 g/mol
Exact mass341.0731
GradeReference Standard
Physical formSolid
XLogP33.4
H-bond donors / acceptors1 / 4
Topological polar surface area50.4 Ų
HS code38229090
InChIKeyZYISITHKPKHPKG-UHFFFAOYSA-N
SMILESCC1=NC=C2N1C3=C(C=C(C=C3)Cl)C(=NC2O)C4=CC=CC=C4F
PubChem CID124449
Synonyms4-OH-Mdz, 4H-Imidazo(1,5-a)(1,4)benzodiazepin-4-ol, 8-chloro-6-(2-fluorophenyl)-1-methyl-, 8-chloro-6-(2-fluorophenyl)-1-methyl-4H-benzo[f]imidazo[1,5-a][1,4]diazepin-4-ol, 4-OH midazolam, 4H-Imidazo[1,5-a][1,4]benzodiazepin-4-ol,8-chloro-6-(2-fluorophenyl)-1-methyl-

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS06 Acute toxicity
Acute toxicity

Signal word Danger

  • H301Toxic if swallowed

Precautionary statements P264, P270, P301 + P316, P321, P330, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of 4-Hydroxy Midazolam
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about 4-Hydroxy Midazolam

Which CAS number identifies 4-Hydroxy Midazolam?
4-Hydroxy Midazolam is registered under CAS 59468-85-8. You may also see it listed as 4-OH-Mdz, 4H-Imidazo(1,5-a)(1,4)benzodiazepin-4-ol, 8-chloro-6-(2-fluorophenyl)-1-methyl-, 8-chloro-6-(2-fluorophenyl)-1-methyl-4H-benzo[f]imidazo[1,5-a][1,4]diazepin-4-ol. Our catalogue number for this item is ZX-036833.
What are the formula and molar mass of 4-Hydroxy Midazolam?
For 4-Hydroxy Midazolam, its formula is C18H13ClFN3O and its molar mass is 341.8 g/mol. The systematic (IUPAC) name is 8-chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepin-4-ol. InChIKey ZYISITHKPKHPKG-UHFFFAOYSA-N lets you match it in any structure database.
How is 4-Hydroxy Midazolam used in pharmaceutical QC?
4-Hydroxy Midazolam is a characterised reference material linked to Midazolam. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for 4-Hydroxy Midazolam?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with 4-Hydroxy Midazolam?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship 4-Hydroxy Midazolam to my country?
Yes. Because 4-Hydroxy Midazolam is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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