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Metabolites & Degradation Products

4-Hydroxythalidomide

Reference StandardAvailable on request

Order 4-Hydroxythalidomide (CAS 5054-59-1) online at Zemixal: C13H10N2O5, COA and SDS with every lot, worldwide shipping.

Pack sizes
4-Hydroxythalidomide chemical structure
CAS number5054-59-1
FormulaC13H10N2O5
Molar mass274.23 g/mol
Physical formSolid
HS code38229090
InChIKeyXMPJICVFSDYOEG-UHFFFAOYSA-N
IUPAC name2-(2,6-dioxopiperidin-3-yl)-4-hydroxyisoindole-1,3-dione

About 4-Hydroxythalidomide

Zemixal lists 4-Hydroxythalidomide for laboratories that identify, quantify or control Thalidomide and its related substances. Identity at a glance (Reference Standard): CAS 5054-59-1, formula C13H10N2O5 and molar mass 274.23 g/mol. It is handled as a solid.

Use cases we see most often

  • Metabolite identification
  • Stability-indicating methods
  • Impurity profiling

Handling and storage

Classified under GHS with signal word Danger and hazard statements H301, H302, H312 and H361. Read the SDS before first use.

Available as 10 mg, 25 mg, 50 mg and 100 mg. Larger or split packs can be arranged. Each lot travels with a certificate of analysis with characterisation data. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.

Reference standards for Thalidomide

See every impurity, metabolite and related compound we list for this API.

Thalidomide standards

Typical uses

  • Metabolite identification
  • Stability-indicating methods
  • Impurity profiling

Applications

Pharmaceutical Manufacturing and QCResearch Labs and Universities

Specifications and identifiers

Specifications of 4-Hydroxythalidomide
Product name4-Hydroxythalidomide
Catalogue numberZX-046318
CAS number5054-59-1
IUPAC name2-(2,6-dioxopiperidin-3-yl)-4-hydroxyisoindole-1,3-dione
Molecular formulaC13H10N2O5
Molar mass274.23 g/mol
Exact mass274.059
GradeReference Standard
Physical formSolid
XLogP30.5
H-bond donors / acceptors2 / 5
Topological polar surface area104 Ų
HS code38229090
InChIKeyXMPJICVFSDYOEG-UHFFFAOYSA-N
SMILESC1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)O
PubChem CID11778087
SynonymsE3 ligase Ligand 2, 2-(2,6-dioxopiperidin-3-yl)-4-hydroxyisoindoline-1,3-dione, Phthalimide, N-(2,6-dioxo-3-piperidyl)-3-hydroxy-, 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-hydroxy-, Thalidomide-4-OH, Thalidomide-OH, 2-(2,6-Dioxo-3-piperidinyl)-4-hydroxyisoindoline-1,3-dione, E3 ligase Ligand 2 (Thalidomide-OH), 2-(2,6-dioxo-3-piperidyl)-4-hydroxy-isoindoline-1,3-dione, 2-(2,6-dioxopiperidin-3-yl)-4-hydroxy-2,3-dihydro-1H-isoindole-1,3-dione

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS06 Acute toxicity
Acute toxicity
GHS07 Irritant or harmful
Irritant or harmful
GHS08 Health hazard
Health hazard

Signal word Danger

  • H301Toxic if swallowed
  • H302Harmful if swallowed
  • H312Harmful in contact with skin
  • H361Suspected of damaging fertility or the unborn child

Precautionary statements P203, P264, P270, P280, P301 + P316, P301 + P317, P302 + P352, P317, P318, P321, P330, P362 + P364, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of 4-Hydroxythalidomide
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about 4-Hydroxythalidomide

Which CAS number identifies 4-Hydroxythalidomide?
4-Hydroxythalidomide is registered under CAS 5054-59-1. You may also see it listed as E3 ligase Ligand 2, 2-(2,6-dioxopiperidin-3-yl)-4-hydroxyisoindoline-1,3-dione, Phthalimide, N-(2,6-dioxo-3-piperidyl)-3-hydroxy-. Our catalogue number for this item is ZX-046318.
What are the formula and molar mass of 4-Hydroxythalidomide?
For 4-Hydroxythalidomide, its formula is C13H10N2O5 and its molar mass is 274.23 g/mol. The systematic (IUPAC) name is 2-(2,6-dioxopiperidin-3-yl)-4-hydroxyisoindole-1,3-dione. InChIKey XMPJICVFSDYOEG-UHFFFAOYSA-N lets you match it in any structure database.
How is 4-Hydroxythalidomide used in pharmaceutical QC?
4-Hydroxythalidomide is a characterised reference material linked to Thalidomide. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for 4-Hydroxythalidomide?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with 4-Hydroxythalidomide?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship 4-Hydroxythalidomide to my country?
Yes. Because 4-Hydroxythalidomide is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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