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Metabolites & Degradation Products

6α-Hydroxy Cortisol

Reference StandardAvailable on request

Order 6α-Hydroxy Cortisol (CAS 2242-98-0) online at Zemixal: C21H30O6, COA and SDS with every lot, worldwide shipping. Catalogue no. ZX-029835.

Pack sizes
6α-Hydroxy Cortisol chemical structure
CAS number2242-98-0
FormulaC21H30O6
Molar mass378.5 g/mol
Physical formSolid
HS code38229090
InChIKeyGNFTWPCIRXSCQF-HVIRSNARSA-N
IUPAC name(6S,8S,9S,10R,11S,13S,14S,17R)-6,11,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one

About 6α-Hydroxy Cortisol

Analytical teams working on Hydrocortisone use 6α-Hydroxy Cortisol as a qualified comparison standard. Key data (Reference Standard): CAS 2242-98-0, formula C21H30O6 and molar mass 378.5 g/mol. It is handled as a solid.

Use cases we see most often

  • Metabolite identification
  • Stability-indicating methods
  • Impurity profiling

Handling and storage

Classified under GHS with signal word Danger and hazard statements H302 and H341. Read the SDS before first use.

Order it in 10 mg, 25 mg, 50 mg and 100 mg packs or ask for a bulk quotation. Every shipment includes a certificate of analysis with characterisation data. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.

Reference standards for Hydrocortisone

See every impurity, metabolite and related compound we list for this API.

Hydrocortisone standards

Typical uses

  • Metabolite identification
  • Stability-indicating methods
  • Impurity profiling

Applications

Specifications and identifiers

Specifications of 6α-Hydroxy Cortisol
Product name6α-Hydroxy Cortisol
Catalogue numberZX-029835
CAS number2242-98-0
IUPAC name(6S,8S,9S,10R,11S,13S,14S,17R)-6,11,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
Molecular formulaC21H30O6
Molar mass378.5 g/mol
Exact mass378.2042
GradeReference Standard
Physical formSolid
XLogP30.3
H-bond donors / acceptors4 / 6
Topological polar surface area115 Ų
HS code38229090
InChIKeyGNFTWPCIRXSCQF-HVIRSNARSA-N
SMILESC[C@]12CCC(=O)C=C1[C@H](C[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CC[C@@]4(C(=O)CO)O)C)O)O
PubChem CID254633
Synonyms6alpha-Hydroxycortisol, 6alpha,11beta,17,21-Tetrahydroxypregn-4-ene-3,20-dione, 6, A-Hydroxycortisol, 6a-Hydroxy Cortisol, 6alpha-Hydroxy Cortisol, 6I+/--Hydroxycortisol, 6alpha-Hydroxyhydrocortisone, 6a,17-Dihydroxy-corticosterone, 6a,11b,17,21-Tetrahydroxy-pregn-4-ene-3,20-dione

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS07 Irritant or harmful
Irritant or harmful
GHS08 Health hazard
Health hazard

Signal word Danger

  • H302Harmful if swallowed
  • H341Suspected of causing genetic defects

Precautionary statements P203, P264, P270, P280, P301 + P317, P318, P330, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of 6α-Hydroxy Cortisol
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about 6α-Hydroxy Cortisol

Which CAS number identifies 6α-Hydroxy Cortisol?
6α-Hydroxy Cortisol is registered under CAS 2242-98-0. You may also see it listed as 6alpha-Hydroxycortisol, 6alpha,11beta,17,21-Tetrahydroxypregn-4-ene-3,20-dione, 6. Our catalogue number for this item is ZX-029835.
What are the formula and molar mass of 6α-Hydroxy Cortisol?
For 6α-Hydroxy Cortisol, its formula is C21H30O6 and its molar mass is 378.5 g/mol. The systematic (IUPAC) name is (6S,8S,9S,10R,11S,13S,14S,17R)-6,11,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one. InChIKey GNFTWPCIRXSCQF-HVIRSNARSA-N lets you match it in any structure database.
How is 6α-Hydroxy Cortisol used in pharmaceutical QC?
6α-Hydroxy Cortisol is a characterised reference material linked to Hydrocortisone. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for 6α-Hydroxy Cortisol?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with 6α-Hydroxy Cortisol?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship 6α-Hydroxy Cortisol to my country?
Yes. Because 6α-Hydroxy Cortisol is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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