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API Impurities

Axitinib Z-isomer

Reference StandardAvailable on request

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Pack sizes
Axitinib Z-isomer chemical structure
CAS number885126-40-9
FormulaC22H18N4OS
Molar mass386.5 g/mol
Physical formSolid
HS code38229090
InChIKeyRITAVMQDGBJQJZ-XFXZXTDPSA-N
IUPAC nameN-methyl-2-[[3-[(Z)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfanyl]benzamide

About Axitinib Z-isomer

Zemixal lists Axitinib Z-isomer for laboratories that identify, quantify or control Axitinib and its related substances. Key data (Reference Standard): CAS 885126-40-9, formula C22H18N4OS and molar mass 386.5 g/mol. It is handled as a solid.

Where it is used

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Safe handling

Hazard communication follows GHS (Warning: H302 and H361). Our SDS lists exposure controls and first-aid measures.

Order it in 10 mg, 25 mg, 50 mg and 100 mg packs or ask for a bulk quotation. Each lot travels with a certificate of analysis with characterisation data. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.

Reference standards for Axitinib

See every impurity, metabolite and related compound we list for this API.

Axitinib standards

Typical uses

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Applications

Specifications and identifiers

Specifications of Axitinib Z-isomer
Product nameAxitinib Z-isomer
Catalogue numberZX-023450
CAS number885126-40-9
IUPAC nameN-methyl-2-[[3-[(Z)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfanyl]benzamide
Molecular formulaC22H18N4OS
Molar mass386.5 g/mol
Exact mass386.1201
GradeReference Standard
Physical formSolid
XLogP34.2
H-bond donors / acceptors2 / 4
Topological polar surface area96 Ų
HS code38229090
InChIKeyRITAVMQDGBJQJZ-XFXZXTDPSA-N
SMILESCNC(=O)C1=CC=CC=C1SC2=CC3=C(C=C2)C(=NN3)/C=C\C4=CC=CC=N4
PubChem CID23724859
SynonymsCis-axitinib, (Z)-Axitinib, N-Methyl-2-((3-((Z)-2-(2-pyridinyl)vinyl)-1H-indazol-6-yl)sulfanyl)benzamide, N-Methyl-2-({3-[(Z)-2-(2-pyridinyl)vinyl]-1H-indazol-6-yl}sulfanyl)benzamide, (Z)-N-Methyl-2-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)benzamide, N-Methyl-2-[[3-[(1Z)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide, Benzamide, N-methyl-2-[[3-[(1Z)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]-, N-methyl-2-[[3-[(Z)-2-(2-pyridyl)vinyl]-1H-indazol-6-yl]sulfanyl]benzamide

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS07 Irritant or harmful
Irritant or harmful
GHS08 Health hazard
Health hazard

Signal word Warning

  • H302Harmful if swallowed
  • H361Suspected of damaging fertility or the unborn child

Precautionary statements P203, P264, P270, P280, P301 + P317, P318, P330, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Axitinib Z-isomer
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Axitinib Z-isomer

Which CAS number identifies Axitinib Z-isomer?
Axitinib Z-isomer is registered under CAS 885126-40-9. You may also see it listed as Cis-axitinib, (Z)-Axitinib, N-Methyl-2-((3-((Z)-2-(2-pyridinyl)vinyl)-1H-indazol-6-yl)sulfanyl)benzamide. Our catalogue number for this item is ZX-023450.
What are the formula and molar mass of Axitinib Z-isomer?
For Axitinib Z-isomer, its formula is C22H18N4OS and its molar mass is 386.5 g/mol. The systematic (IUPAC) name is N-methyl-2-[[3-[(Z)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfanyl]benzamide. InChIKey RITAVMQDGBJQJZ-XFXZXTDPSA-N lets you match it in any structure database.
How is Axitinib Z-isomer used in pharmaceutical QC?
Axitinib Z-isomer is a characterised reference material linked to Axitinib. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Axitinib Z-isomer?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Axitinib Z-isomer?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Axitinib Z-isomer to my country?
Yes. Because Axitinib Z-isomer is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

More Axitinib standards

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