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Metabolites & Degradation Products

Clozapine N-Oxide

Reference StandardAvailable on request

Buy Clozapine N-Oxide (CAS 34233-69-7) from Zemixal: C18H19ClN4O, COA and SDS with every lot, worldwide shipping. Catalogue no. ZX-021282.

Pack sizes
Clozapine N-Oxide chemical structure
CAS number34233-69-7
FormulaC18H19ClN4O
Molar mass342.8 g/mol
Physical formSolid
HS code38229090
InChIKeyOGUCZBIQSYYWEF-UHFFFAOYSA-N
IUPAC name3-chloro-6-(4-methyl-4-oxidopiperazin-4-ium-1-yl)-11H-benzo[b][1,4]benzodiazepine

About Clozapine N-Oxide

Analytical teams working on Clozapine use Clozapine N-Oxide as a qualified comparison standard. For your records (Reference Standard), the material is defined by CAS 34233-69-7, formula C18H19ClN4O and molar mass 342.8 g/mol. It is handled as a solid.

Where it is used

  • Metabolite identification
  • Stability-indicating methods
  • Impurity profiling

Handling and storage

Hazard communication follows GHS (Danger: H301, H315, H319 and H335). Our SDS lists exposure controls and first-aid measures.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and custom quantities are quoted on request. Each lot travels with a certificate of analysis with characterisation data. Request pricing online and we confirm availability, documentation and freight to your country.

Reference standards for Clozapine

See every impurity, metabolite and related compound we list for this API.

Clozapine standards

Typical uses

  • Metabolite identification
  • Stability-indicating methods
  • Impurity profiling

Applications

Pharmaceutical Manufacturing and QCResearch Labs and Universities

Specifications and identifiers

Specifications of Clozapine N-Oxide
Product nameClozapine N-Oxide
Catalogue numberZX-021282
CAS number34233-69-7
IUPAC name3-chloro-6-(4-methyl-4-oxidopiperazin-4-ium-1-yl)-11H-benzo[b][1,4]benzodiazepine
Molecular formulaC18H19ClN4O
Molar mass342.8 g/mol
Exact mass342.1247
GradeReference Standard
Physical formSolid
XLogP32.5
H-bond donors / acceptors1 / 3
Topological polar surface area45.7 Ų
HS code38229090
InChIKeyOGUCZBIQSYYWEF-UHFFFAOYSA-N
SMILESC[N+]1(CCN(CC1)C2=NC3=C(C=CC(=C3)Cl)NC4=CC=CC=C42)[O-]
PubChem CID135445691
Synonyms8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine N-oxide, 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e](1,4)diazepine N-oxide, 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine N-Oxide, 4-(8-chloro-5H-dibenzo[b,e][1,4]diazepin-11-yl)-1-methylpiperazine 1-oxide, 3-chloro-6-(4-methyl-4-oxidopiperazin-4-ium-1-yl)-5H-benzo[b][1,4]benzodiazepine, N-Oxyclozapine, 5H-Dibenzo[b,e][1,4]diazepine, 8-chloro-11-(4-methyl-4-oxido-1-piperazinyl)-, Clozapine-N-oxide (M1), Clozapine N-oxide (CNO chemical), EX-A2353

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS06 Acute toxicity
Acute toxicity
GHS07 Irritant or harmful
Irritant or harmful

Signal word Danger

  • H301Toxic if swallowed
  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements P261, P264, P264 + P265, P270, P271, P280, P301 + P316, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Clozapine N-Oxide
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Clozapine N-Oxide

Which CAS number identifies Clozapine N-Oxide?
Clozapine N-Oxide is registered under CAS 34233-69-7. You may also see it listed as 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine N-oxide, 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e](1,4)diazepine N-oxide, 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine N-Oxide. Our catalogue number for this item is ZX-021282.
What are the formula and molar mass of Clozapine N-Oxide?
For Clozapine N-Oxide, its formula is C18H19ClN4O and its molar mass is 342.8 g/mol. The systematic (IUPAC) name is 3-chloro-6-(4-methyl-4-oxidopiperazin-4-ium-1-yl)-11H-benzo[b][1,4]benzodiazepine. InChIKey OGUCZBIQSYYWEF-UHFFFAOYSA-N lets you match it in any structure database.
How is Clozapine N-Oxide used in pharmaceutical QC?
Clozapine N-Oxide is a characterised reference material linked to Clozapine. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Clozapine N-Oxide?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Clozapine N-Oxide?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Clozapine N-Oxide to my country?
Yes. Because Clozapine N-Oxide is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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