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API Impurities

Cortisone Acetate

Reference StandardAvailable on request

Cortisone Acetate (CAS 50-04-4) supplier Zemixal: C23H30O6, COA and SDS with every lot, worldwide shipping. Catalogue no. ZX-024054.

Pack sizes
Cortisone Acetate chemical structure
CAS number50-04-4
FormulaC23H30O6
Molar mass402.5 g/mol
Physical formSolid
HS code38229090
InChIKeyITRJWOMZKQRYTA-RFZYENFJSA-N
IUPAC name[2-[(8S,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate

About Cortisone Acetate

Zemixal lists Cortisone Acetate for laboratories that identify, quantify or control Hydrocortisone and its related substances. For your records (Reference Standard), the material is defined by CAS 50-04-4, formula C23H30O6 and molar mass 402.5 g/mol. It is handled as a solid.

Where it is used

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Safe handling

Hazard communication follows GHS (Warning: H312, H332 and H361). Our SDS lists exposure controls and first-aid measures.

Available as 10 mg, 25 mg, 50 mg and 100 mg. Larger or split packs can be arranged. Each lot travels with a certificate of analysis with characterisation data. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.

Reference standards for Hydrocortisone

See every impurity, metabolite and related compound we list for this API.

Hydrocortisone standards

Typical uses

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Applications

Pharmaceutical Manufacturing and QCResearch Labs and Universities

Specifications and identifiers

Specifications of Cortisone Acetate
Product nameCortisone Acetate
Catalogue numberZX-024054
CAS number50-04-4
IUPAC name[2-[(8S,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate
Molecular formulaC23H30O6
Molar mass402.5 g/mol
Exact mass402.2042
GradeReference Standard
Physical formSolid
XLogP32.1
H-bond donors / acceptors1 / 6
Topological polar surface area97.7 Ų
HS code38229090
InChIKeyITRJWOMZKQRYTA-RFZYENFJSA-N
SMILESCC(=O)OCC(=O)[C@]1(CC[C@@H]2[C@@]1(CC(=O)[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C)O
PubChem CID5745
SynonymsCortisone 21-Acetate, Cortone acetate, Cortisyl, Pregn-4-ene-3,11,20-trione, 21-(acetyloxy)-17-hydroxy-, Cortisone, 21-acetate, Cortisone aceticum, 17,21-Dihydroxypregn-4-ene-3,11,20-trione 21-acetate, 21-(Acetyloxy)-17-hydroxypregn-4-ene-3,11,20-trione, 17alpha,21-dihydroxypregn-4-ene-3,11,20-trione acetate, 17-Hydroxy-3,11,20-trioxopregn-4-en-21-yl acetate, 6alpha,9Difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate 17-Butyrate, Cortate

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS07 Irritant or harmful
Irritant or harmful
GHS08 Health hazard
Health hazard

Signal word Warning

  • H312Harmful in contact with skin
  • H332Harmful if inhaled
  • H361Suspected of damaging fertility or the unborn child

Precautionary statements P203, P261, P271, P280, P302 + P352, P304 + P340, P317, P318, P321, P362 + P364, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Cortisone Acetate
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Cortisone Acetate

Which CAS number identifies Cortisone Acetate?
Cortisone Acetate is registered under CAS 50-04-4. You may also see it listed as Cortisone 21-Acetate, Cortone acetate, Cortisyl. Our catalogue number for this item is ZX-024054.
What are the formula and molar mass of Cortisone Acetate?
For Cortisone Acetate, its formula is C23H30O6 and its molar mass is 402.5 g/mol. The systematic (IUPAC) name is [2-[(8S,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate. InChIKey ITRJWOMZKQRYTA-RFZYENFJSA-N lets you match it in any structure database.
How is Cortisone Acetate used in pharmaceutical QC?
Cortisone Acetate is a characterised reference material linked to Hydrocortisone. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Cortisone Acetate?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Cortisone Acetate?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Cortisone Acetate to my country?
Yes. Because Cortisone Acetate is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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