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API Impurities

D-Pyroglutamic Acid

Reference StandardAvailable on request

Buy D-Pyroglutamic Acid (CAS 4042-36-8) from Zemixal: C5H7NO3, COA and SDS with every lot, worldwide shipping. Part of our API Impurities range.

Pack sizes
D-Pyroglutamic Acid chemical structure
CAS number4042-36-8
FormulaC5H7NO3
Molar mass129.11 g/mol
Physical formSolid
HS code38229090
InChIKeyODHCTXKNWHHXJC-GSVOUGTGSA-N
IUPAC name(2R)-5-oxopyrrolidine-2-carboxylic acid

About D-Pyroglutamic Acid

Analytical teams working on Allopurinol use D-Pyroglutamic Acid as a qualified comparison standard. Key data (Reference Standard): CAS 4042-36-8, formula C5H7NO3 and molar mass 129.11 g/mol. It is handled as a solid.

Use cases we see most often

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Handling and storage

Classified under GHS with signal word Warning and hazard statements H315, H319 and H335. Read the SDS before first use.

Available as 10 mg, 25 mg, 50 mg and 100 mg. Larger or split packs can be arranged. Every shipment includes a certificate of analysis with characterisation data. Request pricing online and we confirm availability, documentation and freight to your country.

Reference standards for Allopurinol

See every impurity, metabolite and related compound we list for this API.

Allopurinol standards

Typical uses

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Applications

Specifications and identifiers

Specifications of D-Pyroglutamic Acid
Product nameD-Pyroglutamic Acid
Catalogue numberZX-034134
CAS number4042-36-8
IUPAC name(2R)-5-oxopyrrolidine-2-carboxylic acid
Molecular formulaC5H7NO3
Molar mass129.11 g/mol
Exact mass129.0426
GradeReference Standard
Physical formSolid
XLogP3-0.8
H-bond donors / acceptors2 / 3
Topological polar surface area66.4 Ų
HS code38229090
InChIKeyODHCTXKNWHHXJC-GSVOUGTGSA-N
SMILESC1CC(=O)N[C@H]1C(=O)O
PubChem CID439685
Synonyms(R)-(+)-2-Pyrrolidone-5-carboxylic acid, 5-oxo-D-proline, D-Proline, 5-oxo-, D-Pidolic acid, (+)-Pyroglutamic acid, (+)-Pidolic acid, D-5-Pyrrolidone-2-carboxylic acid, D-5-Oxoproline, (R)-5-Oxopyrrolidine-2-carboxylic Acid, D-Pyr-OH, H-D-Pyr-OH

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS07 Irritant or harmful
Irritant or harmful

Signal word Warning

  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of D-Pyroglutamic Acid
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about D-Pyroglutamic Acid

Which CAS number identifies D-Pyroglutamic Acid?
D-Pyroglutamic Acid is registered under CAS 4042-36-8. You may also see it listed as (R)-(+)-2-Pyrrolidone-5-carboxylic acid, 5-oxo-D-proline, D-Proline, 5-oxo-. Our catalogue number for this item is ZX-034134.
What are the formula and molar mass of D-Pyroglutamic Acid?
For D-Pyroglutamic Acid, its formula is C5H7NO3 and its molar mass is 129.11 g/mol. The systematic (IUPAC) name is (2R)-5-oxopyrrolidine-2-carboxylic acid. InChIKey ODHCTXKNWHHXJC-GSVOUGTGSA-N lets you match it in any structure database.
How is D-Pyroglutamic Acid used in pharmaceutical QC?
D-Pyroglutamic Acid is a characterised reference material linked to Allopurinol. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for D-Pyroglutamic Acid?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with D-Pyroglutamic Acid?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship D-Pyroglutamic Acid to my country?
Yes. Because D-Pyroglutamic Acid is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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