2-Amino-N-(3-(5-(2-aminopyrimidin-4-yl)-2-(tert-butyl)thiazol-4-yl)-2-fluorophenyl)-6-fluorobenzenesulfonamide
- CAS
- 2017554-98-0
- Formula
- C23H22F2N6O2S2
- MW
- 516.6 g/mol
ZX-021325
API Reference Standards
Dabrafenib
Reference StandardIn stock
Buy Dabrafenib (CAS 1195765-45-7) from Zemixal: C23H20F3N5O2S2, COA and SDS with every lot, worldwide shipping. Part of our API Reference Standards range.
CAS number1195765-45-7
FormulaC23H20F3N5O2S2
Molar mass519.6 g/mol
Physical formSolid
HS code38229090
InChIKeyBFSMGDJOXZAERB-UHFFFAOYSA-N
IUPAC nameN-[3-[5-(2-aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-4-yl]-2-fluorophenyl]-2,6-difluorobenzenesulfonamide
About Dabrafenib
Dabrafenib belongs to the Dabrafenib reference-standard family in the Zemixal catalogue. Identity at a glance (Reference Standard): CAS 1195765-45-7, formula C23H20F3N5O2S2 and molar mass 519.6 g/mol. It is handled as a solid.
Common uses in the lab and plant
- Identification & assay
- Method development & validation
- QC reference material
Safe handling
It carries the GHS signal word Warning (H361, H373, H400 and H410), so wear gloves and eye protection and work with good ventilation.
Available as 10 mg, 25 mg, 50 mg, 100 mg and 250 mg. Larger or split packs can be arranged. Each lot travels with a certificate of analysis with characterisation data. Add it to your quote list and our team replies with price, lead time and shipping options within one business day.
Reference standards for Dabrafenib
See every impurity, metabolite and related compound we list for this API.
Dabrafenib standardsTypical uses
- Identification & assay
- Method development & validation
- QC reference material
Applications
Specifications and identifiers
| Product name | Dabrafenib |
|---|---|
| Catalogue number | ZX-006481 |
| CAS number | 1195765-45-7 |
| Other CAS numbers | 1195768-06-9 |
| IUPAC name | N-[3-[5-(2-aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-4-yl]-2-fluorophenyl]-2,6-difluorobenzenesulfonamide |
| Molecular formula | C23H20F3N5O2S2 |
| Molar mass | 519.6 g/mol |
| Exact mass | 519.1011 |
| Grade | Reference Standard |
| Physical form | Solid |
| XLogP3 | 4.8 |
| H-bond donors / acceptors | 2 / 11 |
| Topological polar surface area | 147 Ų |
| HS code | 38229090 |
| InChIKey | BFSMGDJOXZAERB-UHFFFAOYSA-N |
| SMILES | CC(C)(C)C1=NC(=C(S1)C2=NC(=NC=C2)N)C3=C(C(=CC=C3)NS(=O)(=O)C4=C(C=CC=C4F)F)F |
| PubChem CID | 44462760 |
| Synonyms | BRAF Inhibitor GSK2118436, Dabrafenib (GSK2118436), Dabrafenib (Free Base), Dabrafenib (USAN), 1195765-45-7 (free base), Dabrafenib (Standard), EX-A1320 |
Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.
Safety and GHS hazards
Signal word Warning
- H361Suspected of damaging fertility or the unborn child
- H373May causes damage to organs through prolonged or repeated exposure
- H400Very toxic to aquatic life
- H410Very toxic to aquatic life with long lasting effects
- H411Toxic to aquatic life with long lasting effects
Precautionary statements P203, P260, P273, P280, P318, P319, P391, P405, P501
Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.
Pack sizes
| 10 mg | Quoted on request | |
| 25 mg | Quoted on request | |
| 50 mg | Quoted on request | |
| 100 mg | Quoted on request | |
| 250 mg | Quoted on request | |
| 500 mg | Quoted on request | |
| 1 g | Quoted on request |
Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.
Questions about Dabrafenib
Which CAS number identifies Dabrafenib?
Dabrafenib is registered under CAS 1195765-45-7. You may also see it listed as BRAF Inhibitor GSK2118436, Dabrafenib (GSK2118436), Dabrafenib (Free Base). Our catalogue number for this item is ZX-006481.
What are the formula and molar mass of Dabrafenib?
For Dabrafenib, its formula is C23H20F3N5O2S2 and its molar mass is 519.6 g/mol. The systematic (IUPAC) name is N-[3-[5-(2-aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-4-yl]-2-fluorophenyl]-2,6-difluorobenzenesulfonamide. InChIKey BFSMGDJOXZAERB-UHFFFAOYSA-N lets you match it in any structure database.
How is Dabrafenib used in pharmaceutical QC?
Dabrafenib is a characterised reference material linked to Dabrafenib. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Dabrafenib?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Dabrafenib?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Dabrafenib to my country?
Yes. Because Dabrafenib is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.
More Dabrafenib standards
More in API Reference Standards
Methyl 3-((2,6-difluorophenyl)sulfonamido)-2-fluorobenzoate
- CAS
- 1195768-19-4
- Formula
- C14H10F3NO4S
- MW
- 345.3 g/mol
ZX-024113
N-(3-(2-(2-Chloropyrimidin-4-yl)acetyl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide
- CAS
- 1195768-20-7
- Formula
- C18H11ClF3N3O3S
- MW
- 441.8 g/mol
ZX-024115
N-(3-(2-(Tert-Butyl)-5-(2-chloropyrimidin-4-yl)thiazol-4-yl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide
- CAS
- 1195768-23-0
- Formula
- C23H18ClF3N4O2S2
- MW
- 539 g/mol
ZX-024116
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