Dihydrocodeine

Name: Dihydrocodeine
Brand: Zemixal
SKU: ZX-047906

Reference StandardAvailable on request

Dihydrocodeine (CAS 125-28-0) supplier Zemixal. Request a quote with price, lead time and documents. Packs from 10 mg. Part of our API Impurities range.

Pack sizes

CAS number125-28-0

FormulaC₁₈H₂₃NO₃

Molar mass301.4 g/mol

Physical formSolid

HS code38229090

InChIKeyRBOXVHNMENFORY-DNJOTXNNSA-N

IUPAC name(4R,4aR,7S,7aR,12bS)-9-methoxy-3-methyl-2,4,4a,5,6,7,7a,13-octahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ol

About Dihydrocodeine

Dihydrocodeine belongs to the Hydrocodone reference-standard family in the Zemixal catalogue. Key data (Reference Standard): CAS 125-28-0, formula C18H23NO3 and molar mass 301.4 g/mol. It is handled as a solid.

Use cases we see most often

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Safe handling

It carries the GHS signal word Danger (H301+H311+H331, H301, H311 and H317), so wear gloves and eye protection and work with good ventilation.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and custom quantities are quoted on request. You receive a certificate of analysis with characterisation data with each order. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.

Reference standards for Hydrocodone

See every impurity, metabolite and related compound we list for this API.

Hydrocodone standards

Typical uses

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Applications

Pharmaceutical Manufacturing and QC Research Labs and Universities

Specifications and identifiers

Specifications of Dihydrocodeine
Product name	Dihydrocodeine
Catalogue number	ZX-047906
CAS number	125-28-0
IUPAC name	(4R,4aR,7S,7aR,12bS)-9-methoxy-3-methyl-2,4,4a,5,6,7,7a,13-octahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ol
Molecular formula	C₁₈H₂₃NO₃
Molar mass	301.4 g/mol
Exact mass	301.1678
Grade	Reference Standard
Physical form	Solid
XLogP3	2.2
H-bond donors / acceptors	1 / 4
Topological polar surface area	41.9 Å²
HS code	38229090
InChIKey	RBOXVHNMENFORY-DNJOTXNNSA-N
SMILES	CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)OC)O[C@H]3[C@H](CC4)O
PubChem CID	5284543
Synonyms	Rapacodin, Novicondin, Codhydrine, Dehacodin, Hydrocodeine, 8,14-Dihydroneopine, Dihydroneopine, Cohydrin, alpha-Hydrocodol, DH-codeine, Morphinan-6-alpha-ol, 4,5-alpha-epoxy-3-methoxy-17-methyl-, Morphinan-6-ol, 4,5-epoxy-3-methoxy-17-methyl-, (5alpha,6alpha)-

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

Acute toxicity

Irritant or harmful

Health hazard

Signal word Danger

H301+H311+H331Toxic if swallowed, in contact with skin or if inhaled
H301Toxic if swallowed
H311Toxic in contact with skin
H317May cause an allergic skin reaction
H331Toxic if inhaled
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements P233, P260, P261, P262, P264, P270, P271, P272, P280, P284, P301 + P316, P302 + P352, P304 + P340, P316, P321, P330, P333 + P317, P342 + P316, P361 + P364, P362 + P364, P403, P403 + P233, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Dihydrocodeine
10 mg	Quoted on request
25 mg	Quoted on request
50 mg	Quoted on request
100 mg	Quoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Dihydrocodeine

Which CAS number identifies Dihydrocodeine?

Dihydrocodeine is registered under CAS 125-28-0. You may also see it listed as Rapacodin, Novicondin, Codhydrine. Our catalogue number for this item is ZX-047906.

What are the formula and molar mass of Dihydrocodeine?

For Dihydrocodeine, its formula is C18H23NO3 and its molar mass is 301.4 g/mol. The systematic (IUPAC) name is (4R,4aR,7S,7aR,12bS)-9-methoxy-3-methyl-2,4,4a,5,6,7,7a,13-octahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ol. InChIKey RBOXVHNMENFORY-DNJOTXNNSA-N lets you match it in any structure database.

How is Dihydrocodeine used in pharmaceutical QC?

Dihydrocodeine is a characterised reference material linked to Hydrocodone. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.

What grade and pack sizes are available for Dihydrocodeine?

This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.

Which documents come with Dihydrocodeine?

Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.

Can Zemixal ship Dihydrocodeine to my country?

Yes. Because Dihydrocodeine is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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