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API Impurities

Dodecamethylcyclohexasiloxane

Reference StandardAvailable on request

Order Dodecamethylcyclohexasiloxane (CAS 540-97-6) online at Zemixal: C12H36O6Si6, COA and SDS with every lot, worldwide shipping.

Pack sizes
Dodecamethylcyclohexasiloxane chemical structure
CAS number540-97-6
FormulaC12H36O6Si6
Molar mass444.92 g/mol
Physical formSolid
HS code38229090
InChIKeyIUMSDRXLFWAGNT-UHFFFAOYSA-N
IUPAC name2,2,4,4,6,6,8,8,10,10,12,12-dodecamethyl-1,3,5,7,9,11-hexaoxa-2,4,6,8,10,12-hexasilacyclododecane

About Dodecamethylcyclohexasiloxane

Dodecamethylcyclohexasiloxane is supplied by Zemixal as a characterised reference material for Cyclomethicone analysis. For your records (Reference Standard), the material is defined by CAS 540-97-6, formula C12H36O6Si6 and molar mass 444.92 g/mol. It is handled as a solid.

Where it is used

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Order it in 10 mg, 25 mg, 50 mg and 100 mg packs or ask for a bulk quotation. Every shipment includes a certificate of analysis with characterisation data. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.

Reference standards for Cyclomethicone

See every impurity, metabolite and related compound we list for this API.

Cyclomethicone standards

Typical uses

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Applications

Specifications and identifiers

Specifications of Dodecamethylcyclohexasiloxane
Product nameDodecamethylcyclohexasiloxane
Catalogue numberZX-028760
CAS number540-97-6
IUPAC name2,2,4,4,6,6,8,8,10,10,12,12-dodecamethyl-1,3,5,7,9,11-hexaoxa-2,4,6,8,10,12-hexasilacyclododecane
Molecular formulaC12H36O6Si6
Molar mass444.92 g/mol
Exact mass444.1127
GradeReference Standard
Physical formSolid
H-bond donors / acceptors0 / 6
Topological polar surface area55.4 Ų
HS code38229090
InChIKeyIUMSDRXLFWAGNT-UHFFFAOYSA-N
SMILESC[Si]1(O[Si](O[Si](O[Si](O[Si](O[Si](O1)(C)C)(C)C)(C)C)(C)C)(C)C)C
PubChem CID10911
SynonymsCyclomethicone 6, Cyclohexasiloxane, dodecamethyl-, Cyclohexasiloxane, 2,2,4,4,6,6,8,8,10,10,12,12-Dodecamethylcyclohexasiloxane, Dodecamethylhexacyclosiloxane, 2,2,4,4,6,6,8,8,10,10,12,12-Dodecamethylcyclohexasiloxane #, cyclohexasiloxane, 2,2,4,4,6,6,8,8,10,10,12,12-dodecamethyl, Cyclohexasiloxane, 2,2,4,4,6,6,8,8,10,10,12,12-dodecamethyl-, 2,2,4,4,6,6,8,8,10,10,12,12-Dodecamethylcyclohexasiloxane, AldrichCPR, 2,2,4,4,6,6,8,8,10,10,12,12-dodecamethyl-1,3,5,7,9,11-hexaoxa-2,4,6,8,10,12-hexa

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

  • H413May cause long lasting harmful effects to aquatic life

Precautionary statements P273, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Dodecamethylcyclohexasiloxane
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Dodecamethylcyclohexasiloxane

Which CAS number identifies Dodecamethylcyclohexasiloxane?
Dodecamethylcyclohexasiloxane is registered under CAS 540-97-6. You may also see it listed as Cyclomethicone 6, Cyclohexasiloxane, dodecamethyl-, Cyclohexasiloxane. Our catalogue number for this item is ZX-028760.
What are the formula and molar mass of Dodecamethylcyclohexasiloxane?
For Dodecamethylcyclohexasiloxane, its formula is C12H36O6Si6 and its molar mass is 444.92 g/mol. The systematic (IUPAC) name is 2,2,4,4,6,6,8,8,10,10,12,12-dodecamethyl-1,3,5,7,9,11-hexaoxa-2,4,6,8,10,12-hexasilacyclododecane. InChIKey IUMSDRXLFWAGNT-UHFFFAOYSA-N lets you match it in any structure database.
How is Dodecamethylcyclohexasiloxane used in pharmaceutical QC?
Dodecamethylcyclohexasiloxane is a characterised reference material linked to Cyclomethicone. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Dodecamethylcyclohexasiloxane?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Dodecamethylcyclohexasiloxane?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Dodecamethylcyclohexasiloxane to my country?
Yes. Dodecamethylcyclohexasiloxane ships worldwide by express courier, air cargo or sea freight, quoted on the Incoterm you prefer, with full export documents.

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