(E)-Methyl 1-acetyl-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate

Name: (E)-Methyl 1-acetyl-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
Brand: Zemixal
SKU: ZX-025844

Reference StandardAvailable on request

(E)-Methyl 1-acetyl-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate (CAS 1168152-07-5) supplier Zemixal…

Pack sizes

(E)-Methyl 1-acetyl-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate chemical structure

CAS number1168152-07-5

FormulaC₂₀H₁₇NO₅

Molar mass351.4 g/mol

Physical formSolid

HS code38229090

InChIKeyIAELOHNWFVWCNO-ISLYRVAYSA-N

IUPAC namemethyl (3E)-1-acetyl-3-[methoxy(phenyl)methylidene]-2-oxoindole-6-carboxylate

About (E)-Methyl 1-acetyl-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate

Analytical teams working on Nintedanib use (E)-Methyl 1-acetyl-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate as a qualified comparison standard. For your records (Reference Standard), the material is defined by CAS 1168152-07-5, formula C20H17NO5 and molar mass 351.4 g/mol. It is handled as a solid.

Common uses in the lab and plant

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Safe handling

It carries the GHS signal word Warning (H302, H312, H332 and H341), so wear gloves and eye protection and work with good ventilation.

Available as 10 mg, 25 mg, 50 mg and 100 mg. Larger or split packs can be arranged. Each lot travels with a certificate of analysis with characterisation data. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.

Reference standards for Nintedanib

See every impurity, metabolite and related compound we list for this API.

Nintedanib standards

Typical uses

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Applications

Pharmaceutical Manufacturing and QC Research Labs and Universities

Specifications and identifiers

Specifications of (E)-Methyl 1-acetyl-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
Product name	(E)-Methyl 1-acetyl-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
Catalogue number	ZX-025844
CAS number	1168152-07-5
IUPAC name	methyl (3E)-1-acetyl-3-[methoxy(phenyl)methylidene]-2-oxoindole-6-carboxylate
Molecular formula	C₂₀H₁₇NO₅
Molar mass	351.4 g/mol
Exact mass	351.1107
Grade	Reference Standard
Physical form	Solid
XLogP3	2.5
H-bond donors / acceptors	0 / 5
Topological polar surface area	72.9 Å²
HS code	38229090
InChIKey	IAELOHNWFVWCNO-ISLYRVAYSA-N
SMILES	CC(=O)N1C2=C(C=CC(=C2)C(=O)OC)/C(=C(/C3=CC=CC=C3)\OC)/C1=O
PubChem CID	44190180
Synonyms	Methyl (3E)-1-acetyl-2,3-dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylate, methyl (3E)-1-acetyl-3-(methoxy(phenyl)methylidene)-2-oxoindole-6-carboxylate, Methyl (E)-1-Acetyl-3-[methoxy(phenyl)methylene]-2-oxoindoline-6-carboxylate, methyl (E)-1-acetyl-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate, CS-M2962, Methyl 1-acetyl-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate, methyl (3E)-1-acetyl-3-[methoxy(phenyl)methylene]-2-oxo-indoline-6-carboxylate, methyl(E)-1-acetyl-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

Irritant or harmful

Health hazard

Signal word Warning

H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled
H341Suspected of causing genetic defects

Precautionary statements P203, P261, P264, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P317, P318, P321, P330, P362 + P364, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of (E)-Methyl 1-acetyl-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
10 mg	Quoted on request
25 mg	Quoted on request
50 mg	Quoted on request
100 mg	Quoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about (E)-Methyl 1-acetyl-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate

Which CAS number identifies (E)-Methyl 1-acetyl-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate?

(E)-Methyl 1-acetyl-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate is registered under CAS 1168152-07-5. You may also see it listed as Methyl (3E)-1-acetyl-2,3-dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylate, methyl (3E)-1-acetyl-3-(methoxy(phenyl)methylidene)-2-oxoindole-6-carboxylate, Methyl (E)-1-Acetyl-3-[methoxy(phenyl)methylene]-2-oxoindoline-6-carboxylate. Our catalogue number for this item is ZX-025844.

What are the formula and molar mass of (E)-Methyl 1-acetyl-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate?

For (E)-Methyl 1-acetyl-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate, its formula is C20H17NO5 and its molar mass is 351.4 g/mol. The systematic (IUPAC) name is methyl (3E)-1-acetyl-3-[methoxy(phenyl)methylidene]-2-oxoindole-6-carboxylate. InChIKey IAELOHNWFVWCNO-ISLYRVAYSA-N lets you match it in any structure database.

How is (E)-Methyl 1-acetyl-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate used in pharmaceutical QC?

(E)-Methyl 1-acetyl-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate is a characterised reference material linked to Nintedanib. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.

What grade and pack sizes are available for (E)-Methyl 1-acetyl-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate?

This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.

Which documents come with (E)-Methyl 1-acetyl-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate?

Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.

Can Zemixal ship (E)-Methyl 1-acetyl-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate to my country?

Yes. Because (E)-Methyl 1-acetyl-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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