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API Process Intermediates & Related Compounds

Hydroxizine

Reference StandardIn stock

Hydroxizine (CAS 68-88-2) supplier Zemixal: C21H27ClN2O2, COA and SDS with every lot, worldwide shipping. Exported from India with full paperwork.

Pack sizes
Hydroxizine chemical structure
CAS number68-88-2
FormulaC21H27ClN2O2
Molar mass374.9 g/mol
Physical formSolid
HS code2933
InChIKeyZQDWXGKKHFNSQK-UHFFFAOYSA-N
IUPAC name2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]ethanol

About Hydroxizine

Hydroxizine is part of the Zemixal API Process Intermediates & Related Compounds range. Identity at a glance (Reference Standard): CAS 68-88-2, formula C21H27ClN2O2 and molar mass 374.9 g/mol. It is handled as a solid.

Use cases we see most often

  • API route development
  • Impurity fate & purge studies
  • Analytical method development

Handling and storage

Classified under GHS with signal word Danger and hazard statements H302, H334, H336 and H360. Read the SDS before first use.

Order it in 10 mg, 25 mg, 50 mg, 100 mg and 250 mg packs or ask for a bulk quotation. Each lot travels with a batch certificate of analysis and a 16-section SDS. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.

Reference standards for Cetirizine

See every impurity, metabolite and related compound we list for this API.

Cetirizine standards

Typical uses

  • API route development
  • Impurity fate & purge studies
  • Analytical method development

Applications

Specifications and identifiers

Specifications of Hydroxizine
Product nameHydroxizine
Catalogue numberZX-012510
CAS number68-88-2
Other CAS numbers1244-76-4
IUPAC name2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]ethanol
Molecular formulaC21H27ClN2O2
Molar mass374.9 g/mol
Exact mass374.1761
GradeReference Standard
Physical formSolid
XLogP33.7
H-bond donors / acceptors1 / 4
Topological polar surface area35.9 Ų
HS code2933
InChIKeyZQDWXGKKHFNSQK-UHFFFAOYSA-N
SMILESC1CN(CCN1CCOCCO)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl
PubChem CID3658
Synonyms2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)ethanol, 2-[2-[4-[(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]ethanol, (±)-Hydroxyzine, 1-(p-Chlorobenzhydryl)-4-[2-(2-hydroxyethoxy)ethyl]piperazine, Hydroxyzine, Hydroxyzyne, Tran-Q, Tranquizine, Hydroxyzin, Hydroxine, Hydroxycine, Hychotine

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS07 Irritant or harmful
Irritant or harmful
GHS08 Health hazard
Health hazard

Signal word Danger

  • H302Harmful if swallowed
  • H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
  • H336May cause drowsiness or dizziness
  • H360May damage fertility or the unborn child
  • H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements P203, P233, P260, P261, P264, P270, P271, P280, P284, P301 + P317, P304 + P340, P318, P319, P330, P342 + P316, P403, P403 + P233, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Hydroxizine
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request
250 mgQuoted on request
500 mgQuoted on request
1 gQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Hydroxizine

Which CAS number identifies Hydroxizine?
Hydroxizine is registered under CAS 68-88-2. You may also see it listed as 2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)ethanol, 2-[2-[4-[(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]ethanol, (±)-Hydroxyzine. Our catalogue number for this item is ZX-012510.
What are the formula and molar mass of Hydroxizine?
For Hydroxizine, its formula is C21H27ClN2O2 and its molar mass is 374.9 g/mol. The systematic (IUPAC) name is 2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]ethanol. InChIKey ZQDWXGKKHFNSQK-UHFFFAOYSA-N lets you match it in any structure database.
How is Hydroxizine used in pharmaceutical QC?
Hydroxizine is a characterised reference material linked to Cetirizine. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Hydroxizine?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Hydroxizine?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Hydroxizine to my country?
Yes. Because Hydroxizine is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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