Ivacaftor

Name: Ivacaftor
Brand: Zemixal
SKU: ZX-006584

Reference StandardIn stock

Order Ivacaftor (CAS 873054-44-5) online at Zemixal: C24H28N2O3, COA and SDS with every lot, worldwide shipping. Catalogue no. ZX-006584.

Pack sizes

CAS number873054-44-5

FormulaC₂₄H₂₈N₂O₃

Molar mass392.5 g/mol

Physical formSolid

HS code38229090

InChIKeyPURKAOJPTOLRMP-UHFFFAOYSA-N

IUPAC nameN-(2,4-ditert-butyl-5-hydroxyphenyl)-4-oxo-1H-quinoline-3-carboxamide

About Ivacaftor

Ivacaftor is supplied by Zemixal as a characterised reference material for Ivacaftor analysis. Key data (Reference Standard): CAS 873054-44-5, formula C24H28N2O3 and molar mass 392.5 g/mol. It is handled as a solid.

Use cases we see most often

Identification & assay
Method development & validation
QC reference material

Safe handling

Classified under GHS with signal word Warning and hazard statements H315, H319, H335 and H361. Read the SDS before first use.

Order it in 10 mg, 25 mg, 50 mg, 100 mg and 250 mg packs or ask for a bulk quotation. You receive a certificate of analysis with characterisation data with each order. Request pricing online and we confirm availability, documentation and freight to your country.

Reference standards for Ivacaftor

See every impurity, metabolite and related compound we list for this API.

Ivacaftor standards

Typical uses

Identification & assay
Method development & validation
QC reference material

Applications

Pharmaceutical Manufacturing and QC Research Labs and Universities

Specifications and identifiers

Specifications of Ivacaftor
Product name	Ivacaftor
Catalogue number	ZX-006584
CAS number	873054-44-5
IUPAC name	N-(2,4-ditert-butyl-5-hydroxyphenyl)-4-oxo-1H-quinoline-3-carboxamide
Molecular formula	C₂₄H₂₈N₂O₃
Molar mass	392.5 g/mol
Exact mass	392.21
Grade	Reference Standard
Physical form	Solid
XLogP3	5.6
H-bond donors / acceptors	3 / 4
Topological polar surface area	78.4 Å²
HS code	38229090
InChIKey	PURKAOJPTOLRMP-UHFFFAOYSA-N
SMILES	CC(C)(C)C1=CC(=C(C=C1NC(=O)C2=CNC3=CC=CC=C3C2=O)O)C(C)(C)C
PubChem CID	16220172
Synonyms	N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide, N-(2,4-Di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide, N-(5-Hydroxy-2,4-di-tert-butylphenyl)-4-oxo-1H-quinoline-3-carboxamide, N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide, N-[2,4-Di(tert-butyl)-5-hydroxyphenyl]-4-oxo-1H,4H-quinoline-3-carboxamide, Kalydeco, VX 770, VX-770, 3-Quinolinecarboxamide, N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxo-, 3-Quinolinecarboxamide, N-(2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl)-1,4-dihydro-4-oxo-, N-(2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide, N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-4-oxo-1,4-dihydroquinoline-3-carboxamide

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

Irritant or harmful

Health hazard

Signal word Warning

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H361Suspected of damaging fertility or the unborn child

Precautionary statements P203, P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P318, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Ivacaftor
10 mg	Quoted on request
25 mg	Quoted on request
50 mg	Quoted on request
100 mg	Quoted on request
250 mg	Quoted on request
500 mg	Quoted on request
1 g	Quoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Ivacaftor

Which CAS number identifies Ivacaftor?

Ivacaftor is registered under CAS 873054-44-5. You may also see it listed as N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide, N-(2,4-Di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide, N-(5-Hydroxy-2,4-di-tert-butylphenyl)-4-oxo-1H-quinoline-3-carboxamide. Our catalogue number for this item is ZX-006584.

What are the formula and molar mass of Ivacaftor?

For Ivacaftor, its formula is C24H28N2O3 and its molar mass is 392.5 g/mol. The systematic (IUPAC) name is N-(2,4-ditert-butyl-5-hydroxyphenyl)-4-oxo-1H-quinoline-3-carboxamide. InChIKey PURKAOJPTOLRMP-UHFFFAOYSA-N lets you match it in any structure database.

How is Ivacaftor used in pharmaceutical QC?

Ivacaftor is a characterised reference material linked to Ivacaftor. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.

What grade and pack sizes are available for Ivacaftor?

This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg. Larger quantities and custom packing can be quoted on request.

Which documents come with Ivacaftor?

Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.

Can Zemixal ship Ivacaftor to my country?

Yes. Because Ivacaftor is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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