Lofepramine

Name: Lofepramine
Brand: Zemixal
SKU: ZX-033752

Reference StandardAvailable on request

Lofepramine (CAS 23047-25-8) supplier Zemixal. Lab and bulk packs, batch COA, fast global delivery. Packs from 10 mg. Catalogue no. ZX-033752.

Pack sizes

CAS number23047-25-8

FormulaC₂₆H₂₇ClN₂O

Molar mass419 g/mol

Physical formSolid

HS code38229090

InChIKeySAPNXPWPAUFAJU-UHFFFAOYSA-N

IUPAC name1-(4-chlorophenyl)-2-[3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl-methylamino]ethanone

About Lofepramine

Lofepramine belongs to the Lofepramine reference-standard family in the Zemixal catalogue. Identity at a glance (Reference Standard): CAS 23047-25-8, formula C26H27ClN2O and molar mass 419 g/mol. It is handled as a solid.

Common uses in the lab and plant

Identification & assay
Method development & validation
QC reference material

Storage and safety notes

Hazard communication follows GHS (Danger: H336, H370 and H373). Our SDS lists exposure controls and first-aid measures.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and custom quantities are quoted on request. Every shipment includes a certificate of analysis with characterisation data. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.

Reference standards for Lofepramine

See every impurity, metabolite and related compound we list for this API.

Lofepramine standards

Typical uses

Identification & assay
Method development & validation
QC reference material

Applications

Pharmaceutical Manufacturing and QC Research Labs and Universities

Specifications and identifiers

Specifications of Lofepramine
Product name	Lofepramine
Catalogue number	ZX-033752
CAS number	23047-25-8
IUPAC name	1-(4-chlorophenyl)-2-[3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl-methylamino]ethanone
Molecular formula	C₂₆H₂₇ClN₂O
Molar mass	419 g/mol
Exact mass	418.1812
Grade	Reference Standard
Physical form	Solid
XLogP3	6.8
H-bond donors / acceptors	0 / 3
Topological polar surface area	23.6 Å²
HS code	38229090
InChIKey	SAPNXPWPAUFAJU-UHFFFAOYSA-N
SMILES	CN(CCCN1C2=CC=CC=C2CCC3=CC=CC=C31)CC(=O)C4=CC=C(C=C4)Cl
PubChem CID	3947
Synonyms	Lopramine, 4'-Chlor-2-((3-(10,11-dihydro-5H-dibenz(b,f)azepin-5-yl)propyl)methylamino)acetophenon, 4'-Chloro-2-[[3-(10,11-dihydro-5H-dibenz[b,f]azepin-5-yl)propyl]methylamino]acetophenone, Leo 640, Acetophenone, 4'-chloro-2-((3-(10,11-dihydro-5H-dibenz(b,f)azepin5-yl)propyl)methylamino)-, 4'-chloro-2-((3-(10,11-dihydro-5H-dibenz(b,f)azepin5-yl)propyl)methylamino)acetophenone, Gamanil (Salt/Mix), Gamonil (Salt/Mix), Timelit (Salt/Mix), Tymelyt (Salt/Mix), Lofepramine - Bio-X trade mark

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

Irritant or harmful

Health hazard

Signal word Danger

H336May cause drowsiness or dizziness
H370Causes damage to organs
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements P260, P261, P264, P270, P271, P304 + P340, P308 + P316, P319, P321, P403 + P233, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Lofepramine
10 mg	Quoted on request
25 mg	Quoted on request
50 mg	Quoted on request
100 mg	Quoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Lofepramine

Which CAS number identifies Lofepramine?

Lofepramine is registered under CAS 23047-25-8. You may also see it listed as Lopramine, 4'-Chlor-2-((3-(10,11-dihydro-5H-dibenz(b,f)azepin-5-yl)propyl)methylamino)acetophenon, 4'-Chloro-2-[[3-(10,11-dihydro-5H-dibenz[b,f]azepin-5-yl)propyl]methylamino]acetophenone. Our catalogue number for this item is ZX-033752.

What are the formula and molar mass of Lofepramine?

For Lofepramine, its formula is C26H27ClN2O and its molar mass is 419 g/mol. The systematic (IUPAC) name is 1-(4-chlorophenyl)-2-[3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl-methylamino]ethanone. InChIKey SAPNXPWPAUFAJU-UHFFFAOYSA-N lets you match it in any structure database.

How is Lofepramine used in pharmaceutical QC?

Lofepramine is a characterised reference material linked to Lofepramine. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.

What grade and pack sizes are available for Lofepramine?

This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.

Which documents come with Lofepramine?

Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.

Can Zemixal ship Lofepramine to my country?

Yes. Because Lofepramine is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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