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API Impurities

Metformin Impurity E (Hydrochloride)

Reference StandardAvailable on request

Metformin Impurity E (Hydrochloride) (CAS 1674-62-0) supplier Zemixal. Request a quote with price, lead time and documents.

Pack sizes
Metformin Impurity E (Hydrochloride) chemical structure
CAS number1674-62-0
FormulaC3H10ClN5
Molar mass151.6 g/mol
Physical formSolid
HS code38229090
InChIKeyAAYCPBAOUJRPIC-UHFFFAOYSA-N
IUPAC name1-(diaminomethylidene)-2-methylguanidine;hydrochloride

About Metformin Impurity E (Hydrochloride)

Metformin Impurity E (Hydrochloride) belongs to the Metformin reference-standard family in the Zemixal catalogue. Key data (Reference Standard): CAS 1674-62-0, formula C3H10ClN5 and molar mass 151.6 g/mol. It is handled as a solid.

Use cases we see most often

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Storage and safety notes

It carries the GHS signal word Warning (H302), so wear gloves and eye protection and work with good ventilation.

Available as 10 mg, 25 mg, 50 mg and 100 mg. Larger or split packs can be arranged. You receive a certificate of analysis with characterisation data with each order. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.

Reference standards for Metformin

See every impurity, metabolite and related compound we list for this API.

Metformin standards

Typical uses

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Applications

Specifications and identifiers

Specifications of Metformin Impurity E (Hydrochloride)
Product nameMetformin Impurity E (Hydrochloride)
Catalogue numberZX-004944
CAS number1674-62-0
IUPAC name1-(diaminomethylidene)-2-methylguanidine;hydrochloride
Molecular formulaC3H10ClN5
Molar mass151.6 g/mol
Exact mass151.0625
GradeReference Standard
Physical formSolid
H-bond donors / acceptors4 / 1
Topological polar surface area103 Ų
HS code38229090
InChIKeyAAYCPBAOUJRPIC-UHFFFAOYSA-N
SMILESCN=C(N)N=C(N)N.Cl
PubChem CID12234208
Synonyms1-Methylbiguanide Hydrochloride, N'-Methylbiguanide monohydrochloride, N-methyl-imidodicarbonimidic Diamide Monohydrochloride, Metformin Related Compound B (USP), 1-Metilbiguanide cloridrato, N-Methylimidodicarbonimidic diamide monohydrochloride, Imidodicarbonimidic diamide, N-methyl-, hydrochloride (1:1), Metformin Related Compoun, Metformin EP Impurity E HCl, Metformin Impurity E HCl Salt, 1-Methylbiguanide hyrdochloride (Metformin RCB), 1-(diaminomethylidene)-3-methylguanidine hydrochloride

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS07 Irritant or harmful
Irritant or harmful

Signal word Warning

  • H302Harmful if swallowed

Precautionary statements P264, P270, P301 + P317, P330, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Metformin Impurity E (Hydrochloride)
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Metformin Impurity E (Hydrochloride)

Which CAS number identifies Metformin Impurity E (Hydrochloride)?
Metformin Impurity E (Hydrochloride) is registered under CAS 1674-62-0. You may also see it listed as 1-Methylbiguanide Hydrochloride, N'-Methylbiguanide monohydrochloride, N-methyl-imidodicarbonimidic Diamide Monohydrochloride. Our catalogue number for this item is ZX-004944.
What are the formula and molar mass of Metformin Impurity E (Hydrochloride)?
For Metformin Impurity E (Hydrochloride), its formula is C3H10ClN5 and its molar mass is 151.6 g/mol. InChIKey AAYCPBAOUJRPIC-UHFFFAOYSA-N lets you match it in any structure database.
How is Metformin Impurity E (Hydrochloride) used in pharmaceutical QC?
Metformin Impurity E (Hydrochloride) is a characterised reference material linked to Metformin. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Metformin Impurity E (Hydrochloride)?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Metformin Impurity E (Hydrochloride)?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Metformin Impurity E (Hydrochloride) to my country?
Yes. Because Metformin Impurity E (Hydrochloride) is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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