Methotrexate α-Ethyl Ester

Name: Methotrexate α-Ethyl Ester
Brand: Zemixal
SKU: ZX-030541

Reference StandardAvailable on request

Methotrexate α-Ethyl Ester (CAS 65148-63-2) supplier Zemixal: C22H26N8O5, COA and SDS with every lot, worldwide shipping.

Pack sizes

Methotrexate α-Ethyl Ester chemical structure

CAS number65148-63-2

FormulaC₂₂H₂₆N₈O₅

Molar mass482.5 g/mol

Physical formSolid

HS code38229090

InChIKeyMVIRCEDDERYMPC-HNNXBMFYSA-N

IUPAC name(4S)-4-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]-5-ethoxy-5-oxopentanoic acid

About Methotrexate α-Ethyl Ester

Methotrexate α-Ethyl Ester is supplied by Zemixal as a characterised reference material for Methotrexate analysis. For your records (Reference Standard), the material is defined by CAS 65148-63-2, formula C22H26N8O5 and molar mass 482.5 g/mol. It is handled as a solid.

Where it is used

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Order it in 10 mg, 25 mg, 50 mg and 100 mg packs or ask for a bulk quotation. Each lot travels with a certificate of analysis with characterisation data. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.

Reference standards for Methotrexate

See every impurity, metabolite and related compound we list for this API.

Methotrexate standards

Typical uses

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Applications

Pharmaceutical Manufacturing and QC Research Labs and Universities

Specifications and identifiers

Specifications of Methotrexate α-Ethyl Ester
Product name	Methotrexate α-Ethyl Ester
Catalogue number	ZX-030541
CAS number	65148-63-2
IUPAC name	(4S)-4-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]-5-ethoxy-5-oxopentanoic acid
Molecular formula	C₂₂H₂₆N₈O₅
Molar mass	482.5 g/mol
Exact mass	482.2026
Grade	Reference Standard
Physical form	Solid
XLogP3	0.3
H-bond donors / acceptors	4 / 12
Topological polar surface area	200 Å²
HS code	38229090
InChIKey	MVIRCEDDERYMPC-HNNXBMFYSA-N
SMILES	CCOC(=O)[C@H](CCC(=O)O)NC(=O)C1=CC=C(C=C1)N(C)CC2=CN=C3C(=N2)C(=NC(=N3)N)N
PubChem CID	90672325
Synonyms	alpha-Monoethyl methotrexate, Methotrexate alpha-monoethyl ester, 1-Ethyl N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamate

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

No GHS classification is on file for this item. Handle it as an unknown laboratory chemical and request the SDS with your quotation.

Pack sizes

Pack sizes of Methotrexate α-Ethyl Ester
10 mg	Quoted on request
25 mg	Quoted on request
50 mg	Quoted on request
100 mg	Quoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Methotrexate α-Ethyl Ester

Which CAS number identifies Methotrexate α-Ethyl Ester?

Methotrexate α-Ethyl Ester is registered under CAS 65148-63-2. You may also see it listed as alpha-Monoethyl methotrexate, Methotrexate alpha-monoethyl ester, 1-Ethyl N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamate. Our catalogue number for this item is ZX-030541.

What are the formula and molar mass of Methotrexate α-Ethyl Ester?

For Methotrexate α-Ethyl Ester, its formula is C22H26N8O5 and its molar mass is 482.5 g/mol. The systematic (IUPAC) name is (4S)-4-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]-5-ethoxy-5-oxopentanoic acid. InChIKey MVIRCEDDERYMPC-HNNXBMFYSA-N lets you match it in any structure database.

How is Methotrexate α-Ethyl Ester used in pharmaceutical QC?

Methotrexate α-Ethyl Ester is a characterised reference material linked to Methotrexate. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.

What grade and pack sizes are available for Methotrexate α-Ethyl Ester?

This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.

Which documents come with Methotrexate α-Ethyl Ester?

Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.

Can Zemixal ship Methotrexate α-Ethyl Ester to my country?

Yes. Methotrexate α-Ethyl Ester ships worldwide by express courier, air cargo or sea freight, quoted on the Incoterm you prefer, with full export documents.

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