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API Impurities

Neostigmine methyl sulphate

Reference StandardAvailable on request

Order Neostigmine methyl sulphate (CAS 51-60-5) online at Zemixal: C13H22N2O6S, COA and SDS with every lot, worldwide shipping.

Pack sizes
Neostigmine methyl sulphate chemical structure
CAS number51-60-5
FormulaC13H22N2O6S
Molar mass334.39 g/mol
Physical formSolid
HS code38229090
InChIKeyOSZNNLWOYWAHSS-UHFFFAOYSA-M
IUPAC name[3-(dimethylcarbamoyloxy)phenyl]-trimethylazanium;methyl sulfate

About Neostigmine methyl sulphate

Neostigmine methyl sulphate is supplied by Zemixal as a characterised reference material for Neostigmine analysis. Identity at a glance (Reference Standard): CAS 51-60-5, formula C13H22N2O6S and molar mass 334.39 g/mol. It is handled as a solid.

Common uses in the lab and plant

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Safe handling

Classified under GHS with signal word Danger and hazard statements H300, H301, H310 and H315. Read the SDS before first use.

Available as 10 mg, 25 mg, 50 mg and 100 mg. Larger or split packs can be arranged. Each lot travels with a certificate of analysis with characterisation data. Add it to your quote list and our team replies with price, lead time and shipping options within one business day.

Reference standards for Neostigmine

See every impurity, metabolite and related compound we list for this API.

Neostigmine standards

Typical uses

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Applications

Specifications and identifiers

Specifications of Neostigmine methyl sulphate
Product nameNeostigmine methyl sulphate
Catalogue numberZX-025794
CAS number51-60-5
IUPAC name[3-(dimethylcarbamoyloxy)phenyl]-trimethylazanium;methyl sulfate
Molecular formulaC13H22N2O6S
Molar mass334.39 g/mol
Exact mass334.1199
GradeReference Standard
Physical formSolid
H-bond donors / acceptors0 / 6
Topological polar surface area104 Ų
HS code38229090
InChIKeyOSZNNLWOYWAHSS-UHFFFAOYSA-M
SMILESCN(C)C(=O)OC1=CC=CC(=C1)[N+](C)(C)C.COS(=O)(=O)[O-]
PubChem CID5824
SynonymsNeostigmine Methyl Sulfate, Neostigmine Metilsulfate, Syntostigmin, Proserine, (m-Hydroxyphenyl)trimethylammonium methyl sulfate dimethylcarbamate, Neostigmini metilsulfas, Benzenaminium, 3-(((dimethylamino)carbonyl)oxy)-N,N,N-trimethyl-, methyl sulfate, Robinul-neostig, Stiglyn 1:500, Methylsulfate, Neostigmine, 3-(Dimethylcarbamoyloxy)-N,N,N-trimethylanilinium methyl sulfate

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS06 Acute toxicity
Acute toxicity
GHS07 Irritant or harmful
Irritant or harmful
GHS08 Health hazard
Health hazard

Signal word Danger

  • H300Fatal if swallowed
  • H301Toxic if swallowed
  • H310Fatal in contact with skin
  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H330Fatal if inhaled
  • H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
  • H335May cause respiratory irritation

Precautionary statements P233, P260, P261, P262, P264, P264 + P265, P270, P271, P280, P284, P301 + P316, P302 + P352, P304 + P340, P305 + P351 + P338, P316, P319, P320, P321, P330, P332 + P317, P337 + P317, P342 + P316, P361 + P364, P362 + P364

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Neostigmine methyl sulphate
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Neostigmine methyl sulphate

Which CAS number identifies Neostigmine methyl sulphate?
Neostigmine methyl sulphate is registered under CAS 51-60-5. You may also see it listed as Neostigmine Methyl Sulfate, Neostigmine Metilsulfate, Syntostigmin. Our catalogue number for this item is ZX-025794.
What are the formula and molar mass of Neostigmine methyl sulphate?
For Neostigmine methyl sulphate, its formula is C13H22N2O6S and its molar mass is 334.39 g/mol. InChIKey OSZNNLWOYWAHSS-UHFFFAOYSA-M lets you match it in any structure database.
How is Neostigmine methyl sulphate used in pharmaceutical QC?
Neostigmine methyl sulphate is a characterised reference material linked to Neostigmine. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Neostigmine methyl sulphate?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Neostigmine methyl sulphate?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Neostigmine methyl sulphate to my country?
Yes. Because Neostigmine methyl sulphate is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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