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API Impurities

Neratinib Impurity 2

Reference StandardAvailable on request

Buy Neratinib Impurity 2 (CAS 848139-78-6) from Zemixal. Lab and bulk packs, batch COA, fast global delivery. Part of our API Impurities range.

Pack sizes
Neratinib Impurity 2 chemical structure
CAS number848139-78-6
FormulaC24H20ClN5O2
Molar mass445.9 g/mol
Physical formSolid
HS code38229090
InChIKeyWRGKROVGVSWJMI-UHFFFAOYSA-N
IUPAC name6-amino-4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-7-ethoxyquinoline-3-carbonitrile

About Neratinib Impurity 2

Neratinib Impurity 2 is supplied by Zemixal as a characterised reference material for Neratinib analysis. Key data (Reference Standard): CAS 848139-78-6, formula C24H20ClN5O2 and molar mass 445.9 g/mol. It is handled as a solid.

Where it is used

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Safe handling

Classified under GHS with signal word Danger and hazard statements H360. Read the SDS before first use.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and custom quantities are quoted on request. Every shipment includes a certificate of analysis with characterisation data. Add it to your quote list and our team replies with price, lead time and shipping options within one business day.

Reference standards for Neratinib

See every impurity, metabolite and related compound we list for this API.

Neratinib standards

Typical uses

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Applications

Specifications and identifiers

Specifications of Neratinib Impurity 2
Product nameNeratinib Impurity 2
Catalogue numberZX-004996
CAS number848139-78-6
Other CAS numbers915942-01-7
IUPAC name6-amino-4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-7-ethoxyquinoline-3-carbonitrile
Molecular formulaC24H20ClN5O2
Molar mass445.9 g/mol
Exact mass445.1306
GradeReference Standard
Physical formSolid
XLogP34.7
H-bond donors / acceptors2 / 7
Topological polar surface area106 Ų
HS code38229090
InChIKeyWRGKROVGVSWJMI-UHFFFAOYSA-N
SMILESCCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)C#N)N
PubChem CID25267648
Synonyms6-Amino-4-[[3-chloro-4-(2-pyridinylmethoxy)phenyl]amino]-7-ethoxy-3-quinolinecarbonitrile, 4-[4-[(2-Pyridyl)methoxy]-3-chloroanilino]-6-amino-3-cyano-7-ethoxyquinoline, 6-Amino-4-[3-chloro-4-[(2-pyridinyl)methoxy]anilino]-3-cyano-7-ethoxyquinoline, 6-Amino-4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-7-ethoxyquinoline-3-carbonitrile, 6-amino-4-(3-chloro-4-(pyrid-2-ylmethoxy)phenylamino)-7-ethoxyquinoline-3-carbonitrile, 6-amino-4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)-7-ethoxyquinoline-3-carbonitrile, 6-amino-4-{[3-chloro-4-(pyridin-2-ylmethoxy)phenyl]amino}-7-ethoxyquinoline-3-carbonitrile, 6-amino-4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7-ethoxy-quinoline-3-carbonitrile, 3-Quinolinecarbonitrile,6-amino-4-[[3-chloro-4-(2-pyridinylmethoxy)phenyl]amino]-7-ethoxy-, 6-Amino-4-((3-chloro-4-(2-pyridinylmethoxy)phenyl)amino)-7-ethoxy-3-quinolinecarbonitrile, Neratinib Impurity N1, CS-M0299

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS08 Health hazard
Health hazard

Signal word Danger

  • H360May damage fertility or the unborn child

Precautionary statements P203, P280, P318, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Neratinib Impurity 2
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Neratinib Impurity 2

Which CAS number identifies Neratinib Impurity 2?
Neratinib Impurity 2 is registered under CAS 848139-78-6. You may also see it listed as 6-Amino-4-[[3-chloro-4-(2-pyridinylmethoxy)phenyl]amino]-7-ethoxy-3-quinolinecarbonitrile, 4-[4-[(2-Pyridyl)methoxy]-3-chloroanilino]-6-amino-3-cyano-7-ethoxyquinoline, 6-Amino-4-[3-chloro-4-[(2-pyridinyl)methoxy]anilino]-3-cyano-7-ethoxyquinoline. Our catalogue number for this item is ZX-004996.
What are the formula and molar mass of Neratinib Impurity 2?
For Neratinib Impurity 2, its formula is C24H20ClN5O2 and its molar mass is 445.9 g/mol. The systematic (IUPAC) name is 6-amino-4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-7-ethoxyquinoline-3-carbonitrile. InChIKey WRGKROVGVSWJMI-UHFFFAOYSA-N lets you match it in any structure database.
How is Neratinib Impurity 2 used in pharmaceutical QC?
Neratinib Impurity 2 is a characterised reference material linked to Neratinib. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Neratinib Impurity 2?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Neratinib Impurity 2?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Neratinib Impurity 2 to my country?
Yes. Because Neratinib Impurity 2 is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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