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API Impurities

Pemetrexed Impurity D(Free Base)

Reference StandardAvailable on request

Buy Pemetrexed Impurity D(Free Base) (CAS 144051-68-3) from Zemixal. Lab and bulk packs, batch COA, fast global delivery.

Pack sizes
Pemetrexed Impurity D(Free Base) chemical structure
CAS number144051-68-3
FormulaC25H28N6O9
Molar mass556.5 g/mol
Physical formSolid
HS code38229090
InChIKeyCOZFORXRWZIVED-HOTGVXAUSA-N
IUPAC name(2S)-2-[[(4S)-4-[[4-[2-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]-4-carboxybutanoyl]amino]pentanedioic acid

About Pemetrexed Impurity D(Free Base)

Zemixal lists Pemetrexed Impurity D(Free Base) for laboratories that identify, quantify or control Pemetrexed and its related substances. Identity at a glance (Reference Standard): CAS 144051-68-3, formula C25H28N6O9 and molar mass 556.5 g/mol. It is handled as a solid.

Common uses in the lab and plant

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Safe handling

Hazard communication follows GHS (Danger: H315, H319, H341 and H360). Our SDS lists exposure controls and first-aid measures.

Available as 10 mg, 25 mg, 50 mg and 100 mg. Larger or split packs can be arranged. Every shipment includes a certificate of analysis with characterisation data. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.

Reference standards for Pemetrexed

See every impurity, metabolite and related compound we list for this API.

Pemetrexed standards

Typical uses

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Applications

Pharmaceutical Manufacturing and QCResearch Labs and Universities

Specifications and identifiers

Specifications of Pemetrexed Impurity D(Free Base)
Product namePemetrexed Impurity D(Free Base)
Catalogue numberZX-005097
CAS number144051-68-3
Other CAS numbers1265908-59-5
IUPAC name(2S)-2-[[(4S)-4-[[4-[2-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]-4-carboxybutanoyl]amino]pentanedioic acid
Molecular formulaC25H28N6O9
Molar mass556.5 g/mol
Exact mass556.1918
GradeReference Standard
Physical formSolid
XLogP3-0.5
H-bond donors / acceptors8 / 10
Topological polar surface area253 Ų
HS code38229090
InChIKeyCOZFORXRWZIVED-HOTGVXAUSA-N
SMILESC1=CC(=CC=C1CCC2=CNC3=C2C(=O)NC(=N3)N)C(=O)N[C@@H](CCC(=O)N[C@@H](CCC(=O)O)C(=O)O)C(=O)O
PubChem CID135877968
SynonymsPemetrexed Impurity D (Free Base), Pemetrexed L-Glutamic Acid, Pemetrexed disodium heptahydrate impurity D, Pemetrexed EP Impurity D, Pemetrexed Impurity D

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS07 Irritant or harmful
Irritant or harmful
GHS08 Health hazard
Health hazard

Signal word Danger

  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H341Suspected of causing genetic defects
  • H360May damage fertility or the unborn child
  • H372Causes damage to organs through prolonged or repeated exposure
  • H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements P203, P260, P264, P264 + P265, P270, P280, P302 + P352, P305 + P351 + P338, P318, P319, P321, P332 + P317, P337 + P317, P362 + P364, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Pemetrexed Impurity D(Free Base)
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Pemetrexed Impurity D(Free Base)

Which CAS number identifies Pemetrexed Impurity D(Free Base)?
Pemetrexed Impurity D(Free Base) is registered under CAS 144051-68-3. You may also see it listed as Pemetrexed Impurity D (Free Base), Pemetrexed L-Glutamic Acid, Pemetrexed disodium heptahydrate impurity D. Our catalogue number for this item is ZX-005097.
What are the formula and molar mass of Pemetrexed Impurity D(Free Base)?
For Pemetrexed Impurity D(Free Base), its formula is C25H28N6O9 and its molar mass is 556.5 g/mol. The systematic (IUPAC) name is (2S)-2-[[(4S)-4-[[4-[2-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]-4-carboxybutanoyl]amino]pentanedioic acid. InChIKey COZFORXRWZIVED-HOTGVXAUSA-N lets you match it in any structure database.
How is Pemetrexed Impurity D(Free Base) used in pharmaceutical QC?
Pemetrexed Impurity D(Free Base) is a characterised reference material linked to Pemetrexed. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Pemetrexed Impurity D(Free Base)?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Pemetrexed Impurity D(Free Base)?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Pemetrexed Impurity D(Free Base) to my country?
Yes. Because Pemetrexed Impurity D(Free Base) is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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