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API Reference Standards

(R,S,S,S)-Nebivolol Hydrochloride

Reference StandardAvailable on request

Buy (R,S,S,S)-Nebivolol Hydrochloride (CAS 920299-33-8) from Zemixal: C22H26ClF2NO4, COA and SDS with every lot, worldwide shipping.

Pack sizes
(R,S,S,S)-Nebivolol Hydrochloride chemical structure
CAS number920299-33-8
FormulaC22H26ClF2NO4
Molar mass441.9 g/mol
Physical formSolid
HS code38229090
InChIKeyJWEXHQAEWHKGCW-BIISKSHESA-N
IUPAC name(1S)-1-[(2R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-[[(2S)-2-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-hydroxyethyl]amino]ethanol;hydrochloride

About (R,S,S,S)-Nebivolol Hydrochloride

(R,S,S,S)-Nebivolol Hydrochloride belongs to the Nebivolol reference-standard family in the Zemixal catalogue. Identity at a glance (Reference Standard): CAS 920299-33-8, formula C22H26ClF2NO4 and molar mass 441.9 g/mol. It is handled as a solid.

Typical applications

  • Identification & assay
  • Method development & validation
  • QC reference material
  • Fine chemical synthesis

Handling and storage

It carries the GHS signal word Warning (H302, H400, H410 and H413), so wear gloves and eye protection and work with good ventilation.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and custom quantities are quoted on request. Every shipment includes a certificate of analysis with characterisation data. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.

Reference standards for Nebivolol

See every impurity, metabolite and related compound we list for this API.

Nebivolol standards

Typical uses

  • Identification & assay
  • Method development & validation
  • QC reference material
  • Fine chemical synthesis

Applications

Specifications and identifiers

Specifications of (R,S,S,S)-Nebivolol Hydrochloride
Product name(R,S,S,S)-Nebivolol Hydrochloride
Catalogue numberZX-030783
CAS number920299-33-8
IUPAC name(1S)-1-[(2R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-[[(2S)-2-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-hydroxyethyl]amino]ethanol;hydrochloride
Molecular formulaC22H26ClF2NO4
Molar mass441.9 g/mol
Exact mass441.1518
GradeReference Standard
Physical formSolid
H-bond donors / acceptors4 / 7
Topological polar surface area71 Ų
HS code38229090
InChIKeyJWEXHQAEWHKGCW-BIISKSHESA-N
SMILESC1CC2=C(C=CC(=C2)F)O[C@H]1[C@H](CNC[C@@H]([C@@H]3CCC4=C(O3)C=CC(=C4)F)O)O.Cl
PubChem CID11626384
SynonymsL-Nebivolol Hydrochloride, Nebivolol (S,R,S,S)-Isomer (HCl salt), rac Nebivolol hydrochloride, Nebivolol (hydrochloride), Nebivolol HCl - Bio-X trade mark, (R,S,S,S)-nebivolol monohydrochloride

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS07 Irritant or harmful
Irritant or harmful
GHS08 Health hazard
Health hazard
GHS09 Hazardous to the environment
Hazardous to the environment

Signal word Warning

  • H302Harmful if swallowed
  • H400Very toxic to aquatic life
  • H410Very toxic to aquatic life with long lasting effects
  • H413May cause long lasting harmful effects to aquatic life

Precautionary statements P203, P264, P270, P273, P280, P301 + P317, P318, P330, P391, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of (R,S,S,S)-Nebivolol Hydrochloride
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about (R,S,S,S)-Nebivolol Hydrochloride

Which CAS number identifies (R,S,S,S)-Nebivolol Hydrochloride?
(R,S,S,S)-Nebivolol Hydrochloride is registered under CAS 920299-33-8. You may also see it listed as L-Nebivolol Hydrochloride, Nebivolol (S,R,S,S)-Isomer (HCl salt), rac Nebivolol hydrochloride. Our catalogue number for this item is ZX-030783.
What are the formula and molar mass of (R,S,S,S)-Nebivolol Hydrochloride?
For (R,S,S,S)-Nebivolol Hydrochloride, its formula is C22H26ClF2NO4 and its molar mass is 441.9 g/mol. InChIKey JWEXHQAEWHKGCW-BIISKSHESA-N lets you match it in any structure database.
How is (R,S,S,S)-Nebivolol Hydrochloride used in pharmaceutical QC?
(R,S,S,S)-Nebivolol Hydrochloride is a characterised reference material linked to Nebivolol. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for (R,S,S,S)-Nebivolol Hydrochloride?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with (R,S,S,S)-Nebivolol Hydrochloride?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship (R,S,S,S)-Nebivolol Hydrochloride to my country?
Yes. Because (R,S,S,S)-Nebivolol Hydrochloride is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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