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API Impurities

Rac-Nebivolol

Reference StandardAvailable on request

Buy Rac-Nebivolol (CAS 99200-09-6) from Zemixal. Lab and bulk packs, batch COA, fast global delivery. Part of our API Impurities range.

Pack sizes
Rac-Nebivolol chemical structure
CAS number99200-09-6
FormulaC22H25F2NO4
Molar mass405.4 g/mol
Physical formSolid
HS code38229090
InChIKeyKOHIRBRYDXPAMZ-UHFFFAOYSA-N
IUPAC name1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)-2-[[2-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)-2-hydroxyethyl]amino]ethanol

About Rac-Nebivolol

Rac-Nebivolol belongs to the Nebivolol reference-standard family in the Zemixal catalogue. Identity at a glance (Reference Standard): CAS 99200-09-6, formula C22H25F2NO4 and molar mass 405.4 g/mol. It is handled as a solid.

Typical applications

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Safe handling

It carries the GHS signal word Warning (H302, H315, H319 and H332), so wear gloves and eye protection and work with good ventilation.

Order it in 10 mg, 25 mg, 50 mg and 100 mg packs or ask for a bulk quotation. You receive a certificate of analysis with characterisation data with each order. Request pricing online and we confirm availability, documentation and freight to your country.

Reference standards for Nebivolol

See every impurity, metabolite and related compound we list for this API.

Nebivolol standards

Typical uses

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Applications

Specifications and identifiers

Specifications of Rac-Nebivolol
Product nameRac-Nebivolol
Catalogue numberZX-025763
CAS number99200-09-6
IUPAC name1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)-2-[[2-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)-2-hydroxyethyl]amino]ethanol
Molecular formulaC22H25F2NO4
Molar mass405.4 g/mol
Exact mass405.1752
GradeReference Standard
Physical formSolid
XLogP33
H-bond donors / acceptors3 / 7
Topological polar surface area71 Ų
HS code38229090
InChIKeyKOHIRBRYDXPAMZ-UHFFFAOYSA-N
SMILESC1CC2=C(C=CC(=C2)F)OC1C(CNCC(C3CCC4=C(O3)C=CC(=C4)F)O)O
PubChem CID71301
SynonymsNebivolol, Narbivolol, dl-Nebivolol, nebibolol, Hydrochloride, Nebivolol, alpha,alpha'-(iminobis(methylene))bis(6-fluoro-3,4-dihydro)-2H-1-benzopyran-2-methanol, 2,2'-Azanediylbis(1-(6-fluorochroman-2-yl)ethanol), 1-(6-fluorochroman-2-yl)-2-[[2-(6-fluorochroman-2-yl)-2-hydroxy-ethyl]amino]ethanol, alpha,alpha'-[iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol], 2,2'-iminobis[1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethanol]

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS07 Irritant or harmful
Irritant or harmful
GHS08 Health hazard
Health hazard

Signal word Warning

  • H302Harmful if swallowed
  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H332Harmful if inhaled
  • H335May cause respiratory irritation
  • H361Suspected of damaging fertility or the unborn child

Precautionary statements P203, P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P318, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Rac-Nebivolol
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Rac-Nebivolol

Which CAS number identifies Rac-Nebivolol?
Rac-Nebivolol is registered under CAS 99200-09-6. You may also see it listed as Nebivolol, Narbivolol, dl-Nebivolol. Our catalogue number for this item is ZX-025763.
What are the formula and molar mass of Rac-Nebivolol?
For Rac-Nebivolol, its formula is C22H25F2NO4 and its molar mass is 405.4 g/mol. The systematic (IUPAC) name is 1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)-2-[[2-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)-2-hydroxyethyl]amino]ethanol. InChIKey KOHIRBRYDXPAMZ-UHFFFAOYSA-N lets you match it in any structure database.
How is Rac-Nebivolol used in pharmaceutical QC?
Rac-Nebivolol is a characterised reference material linked to Nebivolol. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Rac-Nebivolol?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Rac-Nebivolol?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Rac-Nebivolol to my country?
Yes. Because Rac-Nebivolol is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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