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API Reference Standards

Rilpivirine

Reference StandardAvailable on request

Rilpivirine (CAS 500287-72-9) supplier Zemixal. Lab and bulk packs, batch COA, fast global delivery. Part of our API Reference Standards range.

Pack sizes
Rilpivirine chemical structure
CAS number500287-72-9
FormulaC22H18N6
Molar mass366.4 g/mol
Physical formSolid
HS code38229090
InChIKeyYIBOMRUWOWDFLG-ONEGZZNKSA-N
IUPAC name4-[[4-[4-[(E)-2-cyanoethenyl]-2,6-dimethylanilino]pyrimidin-2-yl]amino]benzonitrile

About Rilpivirine

Zemixal lists Rilpivirine for laboratories that identify, quantify or control Rilpivirine and its related substances. Identity at a glance (Reference Standard): CAS 500287-72-9, formula C22H18N6 and molar mass 366.4 g/mol. It is handled as a solid.

Typical applications

  • Identification & assay
  • Method development & validation
  • QC reference material

Handling and storage

It carries the GHS signal word Warning (H302+H312+H332, H302, H312 and H319), so wear gloves and eye protection and work with good ventilation.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and custom quantities are quoted on request. You receive a certificate of analysis with characterisation data with each order. Add it to your quote list and our team replies with price, lead time and shipping options within one business day.

Reference standards for Rilpivirine

See every impurity, metabolite and related compound we list for this API.

Rilpivirine standards

Typical uses

  • Identification & assay
  • Method development & validation
  • QC reference material

Applications

Specifications and identifiers

Specifications of Rilpivirine
Product nameRilpivirine
Catalogue numberZX-006779
CAS number500287-72-9
Other CAS numbers700361-47-3
IUPAC name4-[[4-[4-[(E)-2-cyanoethenyl]-2,6-dimethylanilino]pyrimidin-2-yl]amino]benzonitrile
Molecular formulaC22H18N6
Molar mass366.4 g/mol
Exact mass366.1593
GradeReference Standard
Physical formSolid
XLogP34.5
H-bond donors / acceptors2 / 6
Topological polar surface area97.4 Ų
HS code38229090
InChIKeyYIBOMRUWOWDFLG-ONEGZZNKSA-N
SMILESCC1=CC(=CC(=C1NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C)/C=C/C#N
PubChem CID6451164
Synonyms4-[[4-[[4-[(1E)-2-Cyanoethenyl]-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile, Rekambys, TMC 278, TMC-278, 4-{[4-({4-[(E)-2-cyanovinyl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrile, 4-{[4-({4-[(E)-2-Cyanoethenyl]-2,6-Dimethylphenyl}amino)pyrimidin-2-Yl]amino}benzonitrile, HCl, Rilpivirine, 4-((4-((4-((1E)-2-Cyanoethenyl)-2,6-dimethylphenyl)amino)-2-pyrimidinyl)amino)benzonitrile, 4-{[4-({4-[(1E)-2-Cyanoethenyl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrile, 4-((4-((4-((E)-2-cyanoethenyl)-2,6-dimethylphenyl)amino)pyrimidin-2-yl)amino)benzonitrile, 4-((4-((4-((E)-2-cyanovinyl)-2,6-dimethylphenyl)amino)pyrimidin-2-yl)amino)benzonitrile, Hydrochloride, Rilpivirine

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS07 Irritant or harmful
Irritant or harmful
GHS09 Hazardous to the environment
Hazardous to the environment

Signal word Warning

  • H302+H312+H332Harmful if swallowed, in contact with skin or if inhaled
  • H302Harmful if swallowed
  • H312Harmful in contact with skin
  • H319Causes serious eye irritation
  • H332Harmful if inhaled
  • H400Very toxic to aquatic life
  • H410Very toxic to aquatic life with long lasting effects

Precautionary statements P261, P264, P264 + P265, P270, P271, P273, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P321, P330, P337 + P317, P362 + P364, P391, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Rilpivirine
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Rilpivirine

Which CAS number identifies Rilpivirine?
Rilpivirine is registered under CAS 500287-72-9. You may also see it listed as 4-[[4-[[4-[(1E)-2-Cyanoethenyl]-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile, Rekambys, TMC 278. Our catalogue number for this item is ZX-006779.
What are the formula and molar mass of Rilpivirine?
For Rilpivirine, its formula is C22H18N6 and its molar mass is 366.4 g/mol. The systematic (IUPAC) name is 4-[[4-[4-[(E)-2-cyanoethenyl]-2,6-dimethylanilino]pyrimidin-2-yl]amino]benzonitrile. InChIKey YIBOMRUWOWDFLG-ONEGZZNKSA-N lets you match it in any structure database.
How is Rilpivirine used in pharmaceutical QC?
Rilpivirine is a characterised reference material linked to Rilpivirine. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Rilpivirine?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Rilpivirine?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Rilpivirine to my country?
Yes. Because Rilpivirine is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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