(AS,3S)-a-[(tert-Butyloxycarbonyl)amino]-2-oxo-3-pyrrolidinepropanoic acid Methyl Ester
- CAS
- 328086-60-8
- Formula
- C13H22N2O5
- MW
- 286.32 g/mol
ZX-036862
API Impurities
(S)-3,3-Dimethyl-2-(2,2,2-trifluoroacetamido)butanoic acid
Reference StandardAvailable on request
Buy (S)-3,3-Dimethyl-2-(2,2,2-trifluoroacetamido)butanoic acid (CAS 666832-71-9) from Zemixal: C8H12F3NO3, COA and SDS with every lot, worldwide shipping.
CAS number666832-71-9
FormulaC8H12F3NO3
Molar mass227.18 g/mol
Physical formSolid
HS code38229090
InChIKeyFCTPLAZWXGEGKO-SCSAIBSYSA-N
IUPAC name(2S)-3,3-dimethyl-2-[(2,2,2-trifluoroacetyl)amino]butanoic acid
About (S)-3,3-Dimethyl-2-(2,2,2-trifluoroacetamido)butanoic acid
(S)-3,3-Dimethyl-2-(2,2,2-trifluoroacetamido)butanoic acid is supplied by Zemixal as a characterised reference material for Nirmatrelvir analysis. Identity at a glance (Reference Standard): CAS 666832-71-9, formula C8H12F3NO3 and molar mass 227.18 g/mol. It is handled as a solid.
Where it is used
- Analytical method development
- Method validation (AMV)
- QC release testing
- ANDA / DMF filings
Safe handling
It carries the GHS signal word Warning (H302+H312+H332, H302, H312 and H332), so wear gloves and eye protection and work with good ventilation.
Order it in 10 mg, 25 mg, 50 mg and 100 mg packs or ask for a bulk quotation. Every shipment includes a certificate of analysis with characterisation data. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.
Reference standards for Nirmatrelvir
See every impurity, metabolite and related compound we list for this API.
Nirmatrelvir standardsTypical uses
- Analytical method development
- Method validation (AMV)
- QC release testing
- ANDA / DMF filings
Applications
Specifications and identifiers
| Product name | (S)-3,3-Dimethyl-2-(2,2,2-trifluoroacetamido)butanoic acid |
|---|---|
| Catalogue number | ZX-036726 |
| CAS number | 666832-71-9 |
| IUPAC name | (2S)-3,3-dimethyl-2-[(2,2,2-trifluoroacetyl)amino]butanoic acid |
| Molecular formula | C8H12F3NO3 |
| Molar mass | 227.18 g/mol |
| Exact mass | 227.0769 |
| Grade | Reference Standard |
| Physical form | Solid |
| XLogP3 | 2 |
| H-bond donors / acceptors | 2 / 6 |
| Topological polar surface area | 66.4 Ų |
| HS code | 38229090 |
| InChIKey | FCTPLAZWXGEGKO-SCSAIBSYSA-N |
| SMILES | CC(C)(C)[C@@H](C(=O)O)NC(=O)C(F)(F)F |
| PubChem CID | 61143129 |
| Synonyms | 3-Methyl-N-(trifluoroacetyl)-L-valine, L-Valine, 3-methyl-N-(trifluoroacetyl)-, L-Valine, 3-methyl-N-(trifluoroacetyl)- (9CI), (2S)-3,3-Dimethyl-2-((2,2,2-trifluoroacetyl)amino)butanoic acid, n-trifluoroacetyltert-leucine, (2S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoic acid, (2S)-3,3-dimethyl-2-(trifluoroacetamido)butanoic acid, (2S)-3,3-dimethyl-2-[2,2,2-tris(fluoranyl)ethanoylamino]butanoic acid |
Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.
Safety and GHS hazards
Signal word Warning
- H302+H312+H332Harmful if swallowed, in contact with skin or if inhaled
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
- H373May causes damage to organs through prolonged or repeated exposure
Precautionary statements P260, P261, P264, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P317, P319, P321, P330, P362 + P364, P501
Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.
Pack sizes
| 10 mg | Quoted on request | |
| 25 mg | Quoted on request | |
| 50 mg | Quoted on request | |
| 100 mg | Quoted on request |
Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.
Questions about (S)-3,3-Dimethyl-2-(2,2,2-trifluoroacetamido)butanoic acid
Which CAS number identifies (S)-3,3-Dimethyl-2-(2,2,2-trifluoroacetamido)butanoic acid?
(S)-3,3-Dimethyl-2-(2,2,2-trifluoroacetamido)butanoic acid is registered under CAS 666832-71-9. You may also see it listed as 3-Methyl-N-(trifluoroacetyl)-L-valine, L-Valine, 3-methyl-N-(trifluoroacetyl)-, L-Valine, 3-methyl-N-(trifluoroacetyl)- (9CI). Our catalogue number for this item is ZX-036726.
What are the formula and molar mass of (S)-3,3-Dimethyl-2-(2,2,2-trifluoroacetamido)butanoic acid?
For (S)-3,3-Dimethyl-2-(2,2,2-trifluoroacetamido)butanoic acid, its formula is C8H12F3NO3 and its molar mass is 227.18 g/mol. The systematic (IUPAC) name is (2S)-3,3-dimethyl-2-[(2,2,2-trifluoroacetyl)amino]butanoic acid. InChIKey FCTPLAZWXGEGKO-SCSAIBSYSA-N lets you match it in any structure database.
How is (S)-3,3-Dimethyl-2-(2,2,2-trifluoroacetamido)butanoic acid used in pharmaceutical QC?
(S)-3,3-Dimethyl-2-(2,2,2-trifluoroacetamido)butanoic acid is a characterised reference material linked to Nirmatrelvir. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for (S)-3,3-Dimethyl-2-(2,2,2-trifluoroacetamido)butanoic acid?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with (S)-3,3-Dimethyl-2-(2,2,2-trifluoroacetamido)butanoic acid?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship (S)-3,3-Dimethyl-2-(2,2,2-trifluoroacetamido)butanoic acid to my country?
Yes. Because (S)-3,3-Dimethyl-2-(2,2,2-trifluoroacetamido)butanoic acid is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.
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- CAS
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- CAS
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- Formula
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- MW
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- MW
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ZX-030871
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