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API Impurities

Tamatinib

Reference StandardAvailable on request

Tamatinib (CAS 841290-80-0) supplier Zemixal: C22H23FN6O5, COA and SDS with every lot, worldwide shipping. Catalogue no. ZX-024878.

Pack sizes
Tamatinib chemical structure
CAS number841290-80-0
FormulaC22H23FN6O5
Molar mass470.5 g/mol
Physical formSolid
HS code38229090
InChIKeyNHHQJBCNYHBUSI-UHFFFAOYSA-N
IUPAC name6-[[5-fluoro-2-(3,4,5-trimethoxyanilino)pyrimidin-4-yl]amino]-2,2-dimethyl-4H-pyrido[3,2-b][1,4]oxazin-3-one

About Tamatinib

Tamatinib belongs to the Fostamatinib reference-standard family in the Zemixal catalogue. Identity at a glance (Reference Standard): CAS 841290-80-0, formula C22H23FN6O5 and molar mass 470.5 g/mol. It is handled as a solid.

Where it is used

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Handling and storage

It carries the GHS signal word Danger (H301 and H361), so wear gloves and eye protection and work with good ventilation.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and custom quantities are quoted on request. Every shipment includes a certificate of analysis with characterisation data. Add it to your quote list and our team replies with price, lead time and shipping options within one business day.

Reference standards for Fostamatinib

See every impurity, metabolite and related compound we list for this API.

Fostamatinib standards

Typical uses

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Applications

Specifications and identifiers

Specifications of Tamatinib
Product nameTamatinib
Catalogue numberZX-024878
CAS number841290-80-0
IUPAC name6-[[5-fluoro-2-(3,4,5-trimethoxyanilino)pyrimidin-4-yl]amino]-2,2-dimethyl-4H-pyrido[3,2-b][1,4]oxazin-3-one
Molecular formulaC22H23FN6O5
Molar mass470.5 g/mol
Exact mass470.1714
GradeReference Standard
Physical formSolid
XLogP33.1
H-bond donors / acceptors3 / 11
Topological polar surface area129 Ų
HS code38229090
InChIKeyNHHQJBCNYHBUSI-UHFFFAOYSA-N
SMILESCC1(C(=O)NC2=C(O1)C=CC(=N2)NC3=NC(=NC=C3F)NC4=CC(=C(C(=C4)OC)OC)OC)C
PubChem CID11213558
SynonymsR406 free base, R406 (free base), Tamatinib free base, R406(free base), 3fqs, 3piy, Kinome_1211, EX-A103

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS06 Acute toxicity
Acute toxicity
GHS08 Health hazard
Health hazard

Signal word Danger

  • H301Toxic if swallowed
  • H361Suspected of damaging fertility or the unborn child

Precautionary statements P203, P264, P270, P280, P301 + P316, P318, P321, P330, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Tamatinib
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Tamatinib

Which CAS number identifies Tamatinib?
Tamatinib is registered under CAS 841290-80-0. You may also see it listed as R406 free base, R406 (free base), Tamatinib free base. Our catalogue number for this item is ZX-024878.
What are the formula and molar mass of Tamatinib?
For Tamatinib, its formula is C22H23FN6O5 and its molar mass is 470.5 g/mol. The systematic (IUPAC) name is 6-[[5-fluoro-2-(3,4,5-trimethoxyanilino)pyrimidin-4-yl]amino]-2,2-dimethyl-4H-pyrido[3,2-b][1,4]oxazin-3-one. InChIKey NHHQJBCNYHBUSI-UHFFFAOYSA-N lets you match it in any structure database.
How is Tamatinib used in pharmaceutical QC?
Tamatinib is a characterised reference material linked to Fostamatinib. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Tamatinib?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Tamatinib?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Tamatinib to my country?
Yes. Because Tamatinib is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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