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API Impurities

Thyrotropin-Releasing Hormone (TRH)

Reference StandardAvailable on request

Buy Thyrotropin-Releasing Hormone (TRH) (CAS 24305-27-9) from Zemixal: C16H22N6O4, COA and SDS with every lot, worldwide shipping.

Pack sizes
Thyrotropin-Releasing Hormone (TRH) chemical structure
CAS number24305-27-9
FormulaC16H22N6O4
Molar mass362.38 g/mol
Physical formSolid
HS code38229090
InChIKeyXNSAINXGIQZQOO-SRVKXCTJSA-N
IUPAC name(2S)-N-[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide

About Thyrotropin-Releasing Hormone (TRH)

Zemixal lists Thyrotropin-Releasing Hormone (TRH) for laboratories that identify, quantify or control Protirelin and its related substances. For your records (Reference Standard), the material is defined by CAS 24305-27-9, formula C16H22N6O4 and molar mass 362.38 g/mol. It is handled as a solid.

Where it is used

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Storage and safety notes

Hazard communication follows GHS (Warning: H332). Our SDS lists exposure controls and first-aid measures.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and custom quantities are quoted on request. You receive a certificate of analysis with characterisation data with each order. Add it to your quote list and our team replies with price, lead time and shipping options within one business day.

Reference standards for Protirelin

See every impurity, metabolite and related compound we list for this API.

Protirelin standards

Typical uses

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Applications

Specifications and identifiers

Specifications of Thyrotropin-Releasing Hormone (TRH)
Product nameThyrotropin-Releasing Hormone (TRH)
Catalogue numberZX-036583
CAS number24305-27-9
IUPAC name(2S)-N-[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
Molecular formulaC16H22N6O4
Molar mass362.38 g/mol
Exact mass362.1703
GradeReference Standard
Physical formSolid
XLogP3-2.5
H-bond donors / acceptors4 / 5
Topological polar surface area150 Ų
HS code38229090
InChIKeyXNSAINXGIQZQOO-SRVKXCTJSA-N
SMILESC1C[C@H](N(C1)C(=O)[C@H](CC2=CN=CN2)NC(=O)[C@@H]3CCC(=O)N3)C(=O)N
PubChem CID638678
SynonymsProtirelin, Thyroliberin, Lopremone, Synthetic TRH, Rifathyroin, Thypinone, Thyrotropin-releasing factor, TSH-releasing factor, Protireline, Thyrotropic-releasing factor, 5-Oxo-L-prolyl-L-histidyl-L-prolinamide, Synthetic tsh-releasing factor

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS07 Irritant or harmful
Irritant or harmful

Signal word Warning

  • H332Harmful if inhaled

Precautionary statements P261, P271, P304 + P340, P317

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Thyrotropin-Releasing Hormone (TRH)
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Thyrotropin-Releasing Hormone (TRH)

Which CAS number identifies Thyrotropin-Releasing Hormone (TRH)?
Thyrotropin-Releasing Hormone (TRH) is registered under CAS 24305-27-9. You may also see it listed as Protirelin, Thyroliberin, Lopremone. Our catalogue number for this item is ZX-036583.
What are the formula and molar mass of Thyrotropin-Releasing Hormone (TRH)?
For Thyrotropin-Releasing Hormone (TRH), its formula is C16H22N6O4 and its molar mass is 362.38 g/mol. The systematic (IUPAC) name is (2S)-N-[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide. InChIKey XNSAINXGIQZQOO-SRVKXCTJSA-N lets you match it in any structure database.
How is Thyrotropin-Releasing Hormone (TRH) used in pharmaceutical QC?
Thyrotropin-Releasing Hormone (TRH) is a characterised reference material linked to Protirelin. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Thyrotropin-Releasing Hormone (TRH)?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Thyrotropin-Releasing Hormone (TRH)?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Thyrotropin-Releasing Hormone (TRH) to my country?
Yes. Because Thyrotropin-Releasing Hormone (TRH) is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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