Topotecan Hydrochloride

Name: Topotecan Hydrochloride
Brand: Zemixal
SKU: ZX-032677

Reference StandardAvailable on request

Order Topotecan Hydrochloride (CAS 119413-54-6) online at Zemixal: C23H24ClN3O5, COA and SDS with every lot, worldwide shipping.

Pack sizes

Topotecan Hydrochloride chemical structure

CAS number119413-54-6

FormulaC₂₃H₂₄ClN₃O₅

Molar mass457.9 g/mol

Physical formSolid

HS code38229090

InChIKeyDGHHQBMTXTWTJV-BQAIUKQQSA-N

IUPAC name(19S)-8-[(dimethylamino)methyl]-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione;hydrochloride

About Topotecan Hydrochloride

Topotecan Hydrochloride belongs to the Topotecan reference-standard family in the Zemixal catalogue. Key data (Reference Standard): CAS 119413-54-6, formula C23H24ClN3O5 and molar mass 457.9 g/mol. It is handled as a solid.

Common uses in the lab and plant

Identification & assay
Method development & validation
QC reference material

Storage and safety notes

It carries the GHS signal word Danger (H300, H301, H302 and H315), so wear gloves and eye protection and work with good ventilation.

Order it in 10 mg, 25 mg, 50 mg and 100 mg packs or ask for a bulk quotation. Each lot travels with a certificate of analysis with characterisation data. Add it to your quote list and our team replies with price, lead time and shipping options within one business day.

Reference standards for Topotecan

See every impurity, metabolite and related compound we list for this API.

Topotecan standards

Typical uses

Identification & assay
Method development & validation
QC reference material

Applications

Pharmaceutical Manufacturing and QC Research Labs and Universities

Specifications and identifiers

Specifications of Topotecan Hydrochloride
Product name	Topotecan Hydrochloride
Catalogue number	ZX-032677
CAS number	119413-54-6
IUPAC name	(19S)-8-[(dimethylamino)methyl]-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione;hydrochloride
Molecular formula	C₂₃H₂₄ClN₃O₅
Molar mass	457.9 g/mol
Exact mass	457.1404
Grade	Reference Standard
Physical form	Solid
H-bond donors / acceptors	3 / 7
Topological polar surface area	103 Å²
HS code	38229090
InChIKey	DGHHQBMTXTWTJV-BQAIUKQQSA-N
SMILES	CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=CC5=C(C=CC(=C5CN(C)C)O)N=C4C3=C2)O.Cl
PubChem CID	60699
Synonyms	Topotecan Hcl, Nogitecan hydrochloride, Evotopin, Topotecan teva, Topotecan Actavis, Topotecan Hospira, potactasol, Topotecan (as hydrochloride), Hydrochloride, Nogitecan, Hydrochloride, Topotecan, topotecan hydrochloride (oral), Topotecan Monohydrochloride, (S)-

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

Acute toxicity

Irritant or harmful

Health hazard

Signal word Danger

H300Fatal if swallowed
H301Toxic if swallowed
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H340May cause genetic defects
H350May cause cancer
H351Suspected of causing cancer
H360May damage fertility or the unborn child
H361Suspected of damaging fertility or the unborn child
H370Causes damage to organs
H412Harmful to aquatic life with long lasting effects

Precautionary statements P203, P260, P261, P264, P264 + P265, P270, P271, P273, P280, P301 + P316, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P308 + P316, P318, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Topotecan Hydrochloride
10 mg	Quoted on request
25 mg	Quoted on request
50 mg	Quoted on request
100 mg	Quoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Topotecan Hydrochloride

Which CAS number identifies Topotecan Hydrochloride?

Topotecan Hydrochloride is registered under CAS 119413-54-6. You may also see it listed as Topotecan Hcl, Nogitecan hydrochloride, Evotopin. Our catalogue number for this item is ZX-032677.

What are the formula and molar mass of Topotecan Hydrochloride?

For Topotecan Hydrochloride, its formula is C23H24ClN3O5 and its molar mass is 457.9 g/mol. InChIKey DGHHQBMTXTWTJV-BQAIUKQQSA-N lets you match it in any structure database.

How is Topotecan Hydrochloride used in pharmaceutical QC?

Topotecan Hydrochloride is a characterised reference material linked to Topotecan. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.

What grade and pack sizes are available for Topotecan Hydrochloride?

This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.

Which documents come with Topotecan Hydrochloride?

Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.

Can Zemixal ship Topotecan Hydrochloride to my country?

Yes. Because Topotecan Hydrochloride is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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