Impurity reference standards
Apixaban impurity standards
Page 2 of 2 in the Apixaban hub.
86reference materials
1pharmacopoeial
1nitrosamines
2isotope labelled
All Apixaban reference materials
61–86 of 86 standards
Ethyl (Z)-2-chloro-2-(2-(2-methoxyphenyl)hydrazono)acetate
- CAS
- 2228050-22-2
- Formula
- C11H13ClN2O3
- MW
- 256.68 g/mol
ZX-012468
Ethyl 2-chloro-2-(2-(4-chlorophenyl)hydrazono)acetate
- CAS
- 27143-09-5
- Formula
- C10H10Cl2N2O2
- MW
- 261.1 g/mol
ZX-012472
Ethyl chloro[(4-methoxyphenyl)hydrazono]acetate
- CAS
- 27143-07-3
- Formula
- C11H13ClN2O3
- MW
- 256.68 g/mol
ZX-023327
Ethyl-1-(4-chlorophenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7- tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
- CAS
- 2029205-62-5
- Formula
- C26H25ClN4O4
- MW
- 493 g/mol
ZX-023323
Questions
Apixaban impurities, answered
How many Apixaban impurity standards does Zemixal list?
The catalogue currently lists 86 compounds for Apixaban, including 1 pharmacopoeial impurity, 1 nitrosamine, 2 isotope-labelled standards, 9 metabolites or hydroxylated analogues and 4 degradation products. Each product page shows the CAS number where one is assigned, the structure, formula and molecular weight.
What documents come with a Apixaban impurity standard?
A certificate of analysis travels with every lot. On request we share the characterisation set, usually 1H-NMR, mass spectrum, HPLC purity and IR, and for some materials TGA or water content. Ask for the data before ordering if your QA team needs to review it.
Can Zemixal make a Apixaban impurity that is not listed?
Often yes. Send the structure, name or CAS number with the quantity you need and our sourcing team checks custom synthesis options, usually from 10 mg up to gram scale, with a quoted lead time.
Do you supply Apixaban nitrosamine impurities?
Yes. 1 N-nitroso compound is listed for Apixaban. They are used for confirmatory testing and method validation in line with ICH M7 and the nitrosamine guidance from the major regulators.
Are isotope-labelled Apixaban standards available?
Yes. 2 stable-isotope labelled compounds are listed, suitable as internal standards for LC-MS bioanalysis and trace impurity quantitation.