Nirogacestat

Name: Nirogacestat
Brand: Zemixal
SKU: ZX-006687

Reference StandardAvailable on request

Order Nirogacestat (CAS 1290543-63-3) online at Zemixal. Lab and bulk packs, batch COA, fast global delivery. Packs from 10 mg.

Pack sizes

CAS number1290543-63-3

FormulaC₂₇H₄₁F₂N₅O

Molar mass489.6 g/mol

Physical formSolid

HS code38229090

InChIKeyVFCRKLWBYMDAED-REWPJTCUSA-N

IUPAC name(2S)-2-[[(2S)-6,8-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl]amino]-N-[1-[1-(2,2-dimethylpropylamino)-2-methylpropan-2-yl]imidazol-4-yl]pentanamide

About Nirogacestat

Nirogacestat is supplied by Zemixal as a characterised reference material for Nirogacestat analysis. Identity at a glance (Reference Standard): CAS 1290543-63-3, formula C27H41F2N5O and molar mass 489.6 g/mol. It is handled as a solid.

Use cases we see most often

Identification & assay
Method development & validation
QC reference material

Safe handling

Classified under GHS with signal word Warning and hazard statements H315, H319 and H335. Read the SDS before first use.

Available as 10 mg, 25 mg, 50 mg and 100 mg. Larger or split packs can be arranged. Each lot travels with a certificate of analysis with characterisation data. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.

Reference standards for Nirogacestat

See every impurity, metabolite and related compound we list for this API.

Nirogacestat standards

Typical uses

Identification & assay
Method development & validation
QC reference material

Applications

Pharmaceutical Manufacturing and QC Research Labs and Universities

Specifications and identifiers

Specifications of Nirogacestat
Product name	Nirogacestat
Catalogue number	ZX-006687
CAS number	1290543-63-3
Other CAS numbers	2664906-78-7, 1962925-29-6
IUPAC name	(2S)-2-[[(2S)-6,8-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl]amino]-N-[1-[1-(2,2-dimethylpropylamino)-2-methylpropan-2-yl]imidazol-4-yl]pentanamide
Molecular formula	C₂₇H₄₁F₂N₅O
Molar mass	489.6 g/mol
Exact mass	489.3279
Grade	Reference Standard
Physical form	Solid
XLogP3	4.8
H-bond donors / acceptors	3 / 6
Topological polar surface area	71 Å²
HS code	38229090
InChIKey	VFCRKLWBYMDAED-REWPJTCUSA-N
SMILES	CCC[C@@H](C(=O)NC1=CN(C=N1)C(C)(C)CNCC(C)(C)C)N[C@H]2CCC3=C(C2)C(=CC(=C3)F)F
PubChem CID	46224413
Synonyms	Nirogacestat (USAN/INN), EX-A855, PF-3084014 (y-secratase), EX-A7114, O6U

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

Irritant or harmful

Signal word Warning

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Nirogacestat
10 mg	Quoted on request
25 mg	Quoted on request
50 mg	Quoted on request
100 mg	Quoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Nirogacestat

Which CAS number identifies Nirogacestat?

Nirogacestat is registered under CAS 1290543-63-3. You may also see it listed as Nirogacestat (USAN/INN), EX-A855, PF-3084014 (y-secratase). Our catalogue number for this item is ZX-006687.

What are the formula and molar mass of Nirogacestat?

For Nirogacestat, its formula is C27H41F2N5O and its molar mass is 489.6 g/mol. The systematic (IUPAC) name is (2S)-2-[[(2S)-6,8-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl]amino]-N-[1-[1-(2,2-dimethylpropylamino)-2-methylpropan-2-yl]imidazol-4-yl]pentanamide. InChIKey VFCRKLWBYMDAED-REWPJTCUSA-N lets you match it in any structure database.

How is Nirogacestat used in pharmaceutical QC?

Nirogacestat is a characterised reference material linked to Nirogacestat. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.

What grade and pack sizes are available for Nirogacestat?

This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.

Which documents come with Nirogacestat?

Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.

Can Zemixal ship Nirogacestat to my country?

Yes. Because Nirogacestat is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

More Nirogacestat standards

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