Osimertinib
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About Osimertinib
Zemixal lists Osimertinib for laboratories that identify, quantify or control Osimertinib and its related substances. Key data (Reference Standard): CAS 1421373-65-0, formula C28H33N7O2 and molar mass 499.6 g/mol. It is handled as a solid.
Where it is used
- Identification & assay
- Method development & validation
- QC reference material
Safe handling
It carries the GHS signal word Danger (H302, H317, H360 and H372), so wear gloves and eye protection and work with good ventilation.
Order it in 10 mg, 25 mg, 50 mg, 100 mg and 250 mg packs or ask for a bulk quotation. You receive a certificate of analysis with characterisation data with each order. Add it to your quote list and our team replies with price, lead time and shipping options within one business day.
See every impurity, metabolite and related compound we list for this API.
Osimertinib standardsTypical uses
- Identification & assay
- Method development & validation
- QC reference material
Applications
Specifications and identifiers
| Product name | Osimertinib |
|---|---|
| Catalogue number | ZX-006704 |
| CAS number | 1421373-65-0 |
| Other CAS numbers | 1421373-66-1 |
| IUPAC name | N-[2-[2-(dimethylamino)ethyl-methylamino]-4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamide |
| Molecular formula | C28H33N7O2 |
| Molar mass | 499.6 g/mol |
| Exact mass | 499.2696 |
| Grade | Reference Standard |
| Physical form | Solid |
| XLogP3 | 3.7 |
| H-bond donors / acceptors | 2 / 7 |
| Topological polar surface area | 87.6 Ų |
| HS code | 38229090 |
| InChIKey | DUYJMQONPNNFPI-UHFFFAOYSA-N |
| SMILES | CN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=C(C=C(C(=C4)NC(=O)C=C)N(C)CCN(C)C)OC |
| PubChem CID | 71496458 |
| Synonyms | AZD 9291, Tagrisso, AZD-9291, Osimertinib (AZD9291), AZD 9291(Osimertinib), Osimertinib (Standard), AZD9291 (Osimertinib), mereletinib (obsolete INN), AZD-9291(Osimertinib)?, EX-A314 |
Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.
Safety and GHS hazards
Signal word Danger
- H302Harmful if swallowed
- H317May cause an allergic skin reaction
- H360May damage fertility or the unborn child
- H372Causes damage to organs through prolonged or repeated exposure
- H373May causes damage to organs through prolonged or repeated exposure
- H400Very toxic to aquatic life
- H410Very toxic to aquatic life with long lasting effects
Precautionary statements P203, P260, P261, P264, P270, P272, P273, P280, P301 + P317, P302 + P352, P318, P319, P321, P330, P333 + P317, P362 + P364, P391, P405, P501
Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.
Pack sizes
| 10 mg | Quoted on request | |
| 25 mg | Quoted on request | |
| 50 mg | Quoted on request | |
| 100 mg | Quoted on request | |
| 250 mg | Quoted on request | |
| 500 mg | Quoted on request | |
| 1 g | Quoted on request |
Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.
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