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API Impurities

Phthalic Hydrazide

Reference StandardAvailable on request

Buy Phthalic Hydrazide (CAS 1445-69-8) from Zemixal. Lab and bulk packs, batch COA, fast global delivery. Catalogue no. ZX-025992.

Pack sizes
Phthalic Hydrazide chemical structure
CAS number1445-69-8
FormulaC8H6N2O2
Molar mass162.15 g/mol
Physical formSolid
HS code38229090
InChIKeyKGLPWQKSKUVKMJ-UHFFFAOYSA-N
IUPAC name2,3-dihydrophthalazine-1,4-dione

About Phthalic Hydrazide

Analytical teams working on Rivaroxaban use Phthalic Hydrazide as a qualified comparison standard. For your records (Reference Standard), the material is defined by CAS 1445-69-8, formula C8H6N2O2 and molar mass 162.15 g/mol. It is handled as a solid.

Use cases we see most often

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Handling and storage

Classified under GHS with signal word Warning and hazard statements H302, H315, H319 and H335. Read the SDS before first use.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and custom quantities are quoted on request. You receive a certificate of analysis with characterisation data with each order. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.

Reference standards for Rivaroxaban

See every impurity, metabolite and related compound we list for this API.

Rivaroxaban standards

Typical uses

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Applications

Specifications and identifiers

Specifications of Phthalic Hydrazide
Product namePhthalic Hydrazide
Catalogue numberZX-025992
CAS number1445-69-8
IUPAC name2,3-dihydrophthalazine-1,4-dione
Molecular formulaC8H6N2O2
Molar mass162.15 g/mol
Exact mass162.0429
GradeReference Standard
Physical formSolid
XLogP30.9
H-bond donors / acceptors2 / 2
Topological polar surface area58.2 Ų
HS code38229090
InChIKeyKGLPWQKSKUVKMJ-UHFFFAOYSA-N
SMILESC1=CC=C2C(=C1)C(=O)NNC2=O
PubChem CID219401
SynonymsPhthalhydrazide, 2,3-Dihydro-1,4-phthalazinedione, 1,4-Phthalazinedione, 2,3-dihydro-, 1,4-Phthalazinediol, 2,3-DHPD, Phthalocyclohydrazide, 1,2,3,4-tetrahydrophthalazine-1,4-dione, phthalazine-1,4-diol, Phthalazine-1,4(2H,3H)-dione, 4-hydroxyphthalazin-1(2H)-one, 2,3-dihydro-phthalazine-1,4-dione, 1,4-Dioxo-1,2,3,4-tetrahydrophthalazine

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS07 Irritant or harmful
Irritant or harmful

Signal word Warning

  • H302Harmful if swallowed
  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Phthalic Hydrazide
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Phthalic Hydrazide

Which CAS number identifies Phthalic Hydrazide?
Phthalic Hydrazide is registered under CAS 1445-69-8. You may also see it listed as Phthalhydrazide, 2,3-Dihydro-1,4-phthalazinedione, 1,4-Phthalazinedione, 2,3-dihydro-. Our catalogue number for this item is ZX-025992.
What are the formula and molar mass of Phthalic Hydrazide?
For Phthalic Hydrazide, its formula is C8H6N2O2 and its molar mass is 162.15 g/mol. The systematic (IUPAC) name is 2,3-dihydrophthalazine-1,4-dione. InChIKey KGLPWQKSKUVKMJ-UHFFFAOYSA-N lets you match it in any structure database.
How is Phthalic Hydrazide used in pharmaceutical QC?
Phthalic Hydrazide is a characterised reference material linked to Rivaroxaban. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Phthalic Hydrazide?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Phthalic Hydrazide?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Phthalic Hydrazide to my country?
Yes. Because Phthalic Hydrazide is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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