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API Impurities

5-(4-Bromophenyl)-4,6-dichloropyrimidine

Reference StandardAvailable on request

Order 5-(4-Bromophenyl)-4,6-dichloropyrimidine (CAS 146533-41-7) online at Zemixal: C10H5BrCl2N2, COA and SDS with every lot, worldwide shipping.

Pack sizes
5-(4-Bromophenyl)-4,6-dichloropyrimidine chemical structure
CAS number146533-41-7
FormulaC10H5BrCl2N2
Molar mass303.97 g/mol
Physical formSolid
HS code38229090
InChIKeyWEEFLZORZXLIJE-UHFFFAOYSA-N
IUPAC name5-(4-bromophenyl)-4,6-dichloropyrimidine

About 5-(4-Bromophenyl)-4,6-dichloropyrimidine

Analytical teams working on Macitentan use 5-(4-Bromophenyl)-4,6-dichloropyrimidine as a qualified comparison standard. Key data (Reference Standard): CAS 146533-41-7, formula C10H5BrCl2N2 and molar mass 303.97 g/mol. It is handled as a solid.

Common uses in the lab and plant

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Storage and safety notes

It carries the GHS signal word Warning (H315, H317 and H319), so wear gloves and eye protection and work with good ventilation.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and custom quantities are quoted on request. Each lot travels with a certificate of analysis with characterisation data. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.

Reference standards for Macitentan

See every impurity, metabolite and related compound we list for this API.

Macitentan standards

Typical uses

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Applications

Pharmaceutical Manufacturing and QCResearch Labs and Universities

Specifications and identifiers

Specifications of 5-(4-Bromophenyl)-4,6-dichloropyrimidine
Product name5-(4-Bromophenyl)-4,6-dichloropyrimidine
Catalogue numberZX-022391
CAS number146533-41-7
IUPAC name5-(4-bromophenyl)-4,6-dichloropyrimidine
Molecular formulaC10H5BrCl2N2
Molar mass303.97 g/mol
Exact mass301.9013
GradeReference Standard
Physical formSolid
XLogP34.4
H-bond donors / acceptors0 / 2
Topological polar surface area25.8 Ų
HS code38229090
InChIKeyWEEFLZORZXLIJE-UHFFFAOYSA-N
SMILESC1=CC(=CC=C1C2=C(N=CN=C2Cl)Cl)Br
PubChem CID19735262
SynonymsPyrimidine, 5-(4-bromophenyl)-4,6-dichloro-, 4,6-Dichloro-5-(4-bromophenyl)pyrimidine, CS-M1491, 4,6-dichloro-5-(4-bromophenyl)-pyrimidine

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS07 Irritant or harmful
Irritant or harmful

Signal word Warning

  • H315Causes skin irritation
  • H317May cause an allergic skin reaction
  • H319Causes serious eye irritation

Precautionary statements P261, P264, P264 + P265, P272, P280, P302 + P352, P305 + P351 + P338, P321, P332 + P317, P333 + P317, P337 + P317, P362 + P364, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of 5-(4-Bromophenyl)-4,6-dichloropyrimidine
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about 5-(4-Bromophenyl)-4,6-dichloropyrimidine

Which CAS number identifies 5-(4-Bromophenyl)-4,6-dichloropyrimidine?
5-(4-Bromophenyl)-4,6-dichloropyrimidine is registered under CAS 146533-41-7. You may also see it listed as Pyrimidine, 5-(4-bromophenyl)-4,6-dichloro-, 4,6-Dichloro-5-(4-bromophenyl)pyrimidine, CS-M1491. Our catalogue number for this item is ZX-022391.
What are the formula and molar mass of 5-(4-Bromophenyl)-4,6-dichloropyrimidine?
For 5-(4-Bromophenyl)-4,6-dichloropyrimidine, its formula is C10H5BrCl2N2 and its molar mass is 303.97 g/mol. The systematic (IUPAC) name is 5-(4-bromophenyl)-4,6-dichloropyrimidine. InChIKey WEEFLZORZXLIJE-UHFFFAOYSA-N lets you match it in any structure database.
How is 5-(4-Bromophenyl)-4,6-dichloropyrimidine used in pharmaceutical QC?
5-(4-Bromophenyl)-4,6-dichloropyrimidine is a characterised reference material linked to Macitentan. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for 5-(4-Bromophenyl)-4,6-dichloropyrimidine?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with 5-(4-Bromophenyl)-4,6-dichloropyrimidine?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship 5-(4-Bromophenyl)-4,6-dichloropyrimidine to my country?
Yes. Because 5-(4-Bromophenyl)-4,6-dichloropyrimidine is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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