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API Reference Standards

Ambrisentan

Reference StandardAvailable on request

Order Ambrisentan (CAS 177036-94-1) online at Zemixal. Lab and bulk packs, batch COA, fast global delivery. Part of our API Reference Standards range.

Pack sizes
Ambrisentan chemical structure
CAS number177036-94-1
FormulaC22H22N2O4
Molar mass378.4 g/mol
Physical formSolid
HS code38229090
InChIKeyOUJTZYPIHDYQMC-LJQANCHMSA-N
IUPAC name(2S)-2-(4,6-dimethylpyrimidin-2-yl)oxy-3-methoxy-3,3-diphenylpropanoic acid

About Ambrisentan

Ambrisentan belongs to the Ambrisentan reference-standard family in the Zemixal catalogue. Identity at a glance (Reference Standard): CAS 177036-94-1, formula C22H22N2O4 and molar mass 378.4 g/mol. It is handled as a solid.

Use cases we see most often

  • Identification & assay
  • Method development & validation
  • QC reference material

Handling and storage

Hazard communication follows GHS (Danger: H351, H361 and H372). Our SDS lists exposure controls and first-aid measures.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and custom quantities are quoted on request. You receive a certificate of analysis with characterisation data with each order. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.

Reference standards for Ambrisentan

See every impurity, metabolite and related compound we list for this API.

Ambrisentan standards

Typical uses

  • Identification & assay
  • Method development & validation
  • QC reference material

Applications

Pharmaceutical Manufacturing and QCResearch Labs and Universities

Specifications and identifiers

Specifications of Ambrisentan
Product nameAmbrisentan
Catalogue numberZX-020579
CAS number177036-94-1
IUPAC name(2S)-2-(4,6-dimethylpyrimidin-2-yl)oxy-3-methoxy-3,3-diphenylpropanoic acid
Molecular formulaC22H22N2O4
Molar mass378.4 g/mol
Exact mass378.158
GradeReference Standard
Physical formSolid
XLogP33.8
H-bond donors / acceptors1 / 6
Topological polar surface area81.5 Ų
HS code38229090
InChIKeyOUJTZYPIHDYQMC-LJQANCHMSA-N
SMILESCC1=CC(=NC(=N1)O[C@H](C(=O)O)C(C2=CC=CC=C2)(C3=CC=CC=C3)OC)C
PubChem CID6918493
Synonyms(2s)-2-[(4,6-dimethylpyrimidin-2-yl)oxy]-3-methoxy-3,3-diphenylpropanoic acid, (+-)-(2S)-2-((4,6-Dimethylpyrimidin-2-yl)oxy)-3-methoxy-3,3-diphenylpropanoic acid, (+)-(2S)-2-((4,6-dimethylpyrimidin-2-yl)oxy)-3-methoxy-3,3-diphenylpropanoic acid, (+)-(2s)-2-[(4,6-dimethylpyrimidin-2-yl)oxy]-3-methoxy-3,3-diphenylpropanoic acid, (2S)-2-(4,6-dimethylpyrimidin-2-yl)oxy-3-methoxy-3,3-di(phenyl)propanoic acid, (S)-ambrisentan, (2S)-2-((4,6-Dimethylpyrimidin-2-yl)oxy)-3-methoxy-3,3-diphenylpropanoic acid, (S)-2-((4,6-Dimethylpyrimidin-2-yl)oxy)-3-methoxy-3,3-diphenylpropanoic acid, (S)-2-(4,6-Dimethylpyrimidin-2-yloxy)-3-methoxy-3,3-diphenylpropanoic acid, (s)-2-[(4,6-dimethylpyrimidin-2-yl)oxy]-3-methoxy-3,3-diphenylpropionic acid

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS08 Health hazard
Health hazard

Signal word Danger

  • H351Suspected of causing cancer
  • H361Suspected of damaging fertility or the unborn child
  • H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements P203, P260, P264, P270, P280, P318, P319, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Ambrisentan
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Ambrisentan

Which CAS number identifies Ambrisentan?
Ambrisentan is registered under CAS 177036-94-1. You may also see it listed as (2s)-2-[(4,6-dimethylpyrimidin-2-yl)oxy]-3-methoxy-3,3-diphenylpropanoic acid, (+-)-(2S)-2-((4,6-Dimethylpyrimidin-2-yl)oxy)-3-methoxy-3,3-diphenylpropanoic acid, (+)-(2S)-2-((4,6-dimethylpyrimidin-2-yl)oxy)-3-methoxy-3,3-diphenylpropanoic acid. Our catalogue number for this item is ZX-020579.
What are the formula and molar mass of Ambrisentan?
For Ambrisentan, its formula is C22H22N2O4 and its molar mass is 378.4 g/mol. The systematic (IUPAC) name is (2S)-2-(4,6-dimethylpyrimidin-2-yl)oxy-3-methoxy-3,3-diphenylpropanoic acid. InChIKey OUJTZYPIHDYQMC-LJQANCHMSA-N lets you match it in any structure database.
How is Ambrisentan used in pharmaceutical QC?
Ambrisentan is a characterised reference material linked to Ambrisentan. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Ambrisentan?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Ambrisentan?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Ambrisentan to my country?
Yes. Because Ambrisentan is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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