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API Reference Standards

Levothyroxine Sodium Hydrate

Reference StandardAvailable on request

Levothyroxine Sodium Hydrate (CAS 25416-65-3) supplier Zemixal: C15H12I4NNaO5, COA and SDS with every lot, worldwide shipping.

Pack sizes
Levothyroxine Sodium Hydrate chemical structure
CAS number25416-65-3
FormulaC15H12I4NNaO5
Molar mass816.87 g/mol
Physical formSolid
HS code38229090
InChIKeyANMYAHDLKVNJJO-LTCKWSDVSA-M
IUPAC namesodium;(2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate;hydrate

About Levothyroxine Sodium Hydrate

Levothyroxine Sodium Hydrate belongs to the Levothyroxine reference-standard family in the Zemixal catalogue. Identity at a glance (Reference Standard): CAS 25416-65-3, formula C15H12I4NNaO5 and molar mass 816.87 g/mol. It is handled as a solid.

Common uses in the lab and plant

  • Identification & assay
  • Method development & validation
  • QC reference material

Safe handling

It carries the GHS signal word Danger (H361, H372 and H373), so wear gloves and eye protection and work with good ventilation.

Order it in 10 mg, 25 mg, 50 mg and 100 mg packs or ask for a bulk quotation. Each lot travels with a certificate of analysis with characterisation data. Request pricing online and we confirm availability, documentation and freight to your country.

Reference standards for Levothyroxine

See every impurity, metabolite and related compound we list for this API.

Levothyroxine standards

Typical uses

  • Identification & assay
  • Method development & validation
  • QC reference material

Applications

Pharmaceutical Manufacturing and QCResearch Labs and Universities

Specifications and identifiers

Specifications of Levothyroxine Sodium Hydrate
Product nameLevothyroxine Sodium Hydrate
Catalogue numberZX-036485
CAS number25416-65-3
IUPAC namesodium;(2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate;hydrate
Molecular formulaC15H12I4NNaO5
Molar mass816.87 g/mol
Exact mass816.6792
GradeReference Standard
Physical formSolid
H-bond donors / acceptors3 / 6
Topological polar surface area96.6 Ų
HS code38229090
InChIKeyANMYAHDLKVNJJO-LTCKWSDVSA-M
SMILESC1=C(C=C(C(=C1I)OC2=CC(=C(C(=C2)I)O)I)I)C[C@@H](C(=O)[O-])N.O.[Na+]
PubChem CID23667619
SynonymsLevothyroxine sodium monohydrate, L-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, monosodium salt, monohydrate, L-Thyroxine sodium xhydrate, L-Thyroxine sodium hydrate, Sodium (S)-2-amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)propanoate xhydrate, L-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, monosodium salt, hydrate, Levoroxin, Tivoral, O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine Sodium Salt Hydrate, Sodium (S)-2-amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)propanoate hydrate, Levo-Tiroxina Glaxo, L-thyroxine sodium salt monohydrate

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS08 Health hazard
Health hazard

Signal word Danger

  • H361Suspected of damaging fertility or the unborn child
  • H372Causes damage to organs through prolonged or repeated exposure
  • H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements P203, P260, P264, P270, P280, P318, P319, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Levothyroxine Sodium Hydrate
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Levothyroxine Sodium Hydrate

Which CAS number identifies Levothyroxine Sodium Hydrate?
Levothyroxine Sodium Hydrate is registered under CAS 25416-65-3. You may also see it listed as Levothyroxine sodium monohydrate, L-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, monosodium salt, monohydrate, L-Thyroxine sodium xhydrate. Our catalogue number for this item is ZX-036485.
What are the formula and molar mass of Levothyroxine Sodium Hydrate?
For Levothyroxine Sodium Hydrate, its formula is C15H12I4NNaO5 and its molar mass is 816.87 g/mol. InChIKey ANMYAHDLKVNJJO-LTCKWSDVSA-M lets you match it in any structure database.
How is Levothyroxine Sodium Hydrate used in pharmaceutical QC?
Levothyroxine Sodium Hydrate is a characterised reference material linked to Levothyroxine. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Levothyroxine Sodium Hydrate?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Levothyroxine Sodium Hydrate?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Levothyroxine Sodium Hydrate to my country?
Yes. Because Levothyroxine Sodium Hydrate is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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