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API Process Intermediates & Related Compounds

H-Thr(tBu)-OH

Available on request

H-Thr(tBu)-OH (CAS 4378-13-6) supplier Zemixal. Lab and bulk packs, batch COA, fast global delivery. Catalogue no. ZX-042181.

Pack sizes
H-Thr(tBu)-OH chemical structure
CAS number4378-13-6
FormulaC8H17NO3
Molar mass175.23 g/mol
Physical formSolid
InChIKeyNMJINEMBBQVPGY-RITPCOANSA-N
IUPAC name(2S,3R)-2-amino-3-[(2-methylpropan-2-yl)oxy]butanoic acid

About H-Thr(tBu)-OH

H-Thr(tBu)-OH sits in our API Process Intermediates & Related Compounds section and ships worldwide from stock or short lead time. Key data: CAS 4378-13-6, formula C8H17NO3 and molar mass 175.23 g/mol. It is handled as a solid.

Use cases we see most often

  • API route development
  • Impurity fate & purge studies
  • Analytical method development

Safe handling

It carries the GHS signal word Warning (H315, H319 and H335), so wear gloves and eye protection and work with good ventilation.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and custom quantities are quoted on request. Every shipment includes a batch certificate of analysis and a 16-section SDS. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.

Reference standards for Threonine

See every impurity, metabolite and related compound we list for this API.

Threonine standards

Typical uses

  • API route development
  • Impurity fate & purge studies
  • Analytical method development

Applications

Pharmaceutical Manufacturing and QCResearch Labs and Universities

Specifications and identifiers

Specifications of H-Thr(tBu)-OH
Product nameH-Thr(tBu)-OH
Catalogue numberZX-042181
CAS number4378-13-6
IUPAC name(2S,3R)-2-amino-3-[(2-methylpropan-2-yl)oxy]butanoic acid
Molecular formulaC8H17NO3
Molar mass175.23 g/mol
Exact mass175.1208
Physical formSolid
XLogP3-2.1
H-bond donors / acceptors2 / 4
Topological polar surface area72.6 Ų
InChIKeyNMJINEMBBQVPGY-RITPCOANSA-N
SMILESC[C@H]([C@@H](C(=O)O)N)OC(C)(C)C
PubChem CID6951357
SynonymsO-tert-Butyl-L-Threonine, (2S,3R)-2-Amino-3-(tert-butoxy)butanoic acid, O-(1,1-Dimethylethyl)-L-threonine, O-(tert-Butyl)-L-threonine, L-Threonine, O-(1,1-dimethylethyl)-, O-t-Butyl-L-threonine, O-tert-Butyl-L-allo-threonine, (2S,3R)-2-Amino-3-(tert-butoxy)butanoicacid, O-tert.Butyl-L-threonine, (2S,3R)-2-azaniumyl-3-[(2-methylpropan-2-yl)oxy]butanoate, O-tert.-Butylthreonin, Threonine tert-butyl ether

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS07 Irritant or harmful
Irritant or harmful

Signal word Warning

  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of H-Thr(tBu)-OH
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about H-Thr(tBu)-OH

Which CAS number identifies H-Thr(tBu)-OH?
H-Thr(tBu)-OH is registered under CAS 4378-13-6. You may also see it listed as O-tert-Butyl-L-Threonine, (2S,3R)-2-Amino-3-(tert-butoxy)butanoic acid, O-(1,1-Dimethylethyl)-L-threonine. Our catalogue number for this item is ZX-042181.
What are the formula and molar mass of H-Thr(tBu)-OH?
For H-Thr(tBu)-OH, its formula is C8H17NO3 and its molar mass is 175.23 g/mol. The systematic (IUPAC) name is (2S,3R)-2-amino-3-[(2-methylpropan-2-yl)oxy]butanoic acid. InChIKey NMJINEMBBQVPGY-RITPCOANSA-N lets you match it in any structure database.
How is H-Thr(tBu)-OH used in pharmaceutical QC?
H-Thr(tBu)-OH is a characterised reference material linked to Threonine. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for H-Thr(tBu)-OH?
The grade and assay are confirmed on the quotation and the batch COA. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with H-Thr(tBu)-OH?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship H-Thr(tBu)-OH to my country?
Yes. Because H-Thr(tBu)-OH is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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