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API Impurities

Valsartan Impurity 8 (Hydrochloride)

Reference StandardIn stock

Buy Valsartan Impurity 8 (Hydrochloride) (CAS 482577-59-3) from Zemixal. Request a quote with price, lead time and documents.

Pack sizes
Valsartan Impurity 8 (Hydrochloride) chemical structure
CAS number482577-59-3
FormulaC20H23ClN2O2
Molar mass358.9 g/mol
Physical formSolid
HS code38229090
InChIKeyAZQXUWUZQLZNIM-FYZYNONXSA-N
IUPAC namemethyl (2S)-2-[[4-(2-cyanophenyl)phenyl]methylamino]-3-methylbutanoate;hydrochloride

About Valsartan Impurity 8 (Hydrochloride)

Valsartan Impurity 8 (Hydrochloride) belongs to the Valsartan reference-standard family in the Zemixal catalogue. For your records (Reference Standard), the material is defined by CAS 482577-59-3, formula C20H23ClN2O2 and molar mass 358.9 g/mol. It is handled as a solid.

Where it is used

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Storage and safety notes

Hazard communication follows GHS (Warning: H302+H312+H332, H302, H312 and H315). Our SDS lists exposure controls and first-aid measures.

Order it in 10 mg, 25 mg, 50 mg, 100 mg and 250 mg packs or ask for a bulk quotation. You receive a certificate of analysis with characterisation data with each order. Request pricing online and we confirm availability, documentation and freight to your country.

Reference standards for Valsartan

See every impurity, metabolite and related compound we list for this API.

Valsartan standards

Typical uses

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Applications

Specifications and identifiers

Specifications of Valsartan Impurity 8 (Hydrochloride)
Product nameValsartan Impurity 8 (Hydrochloride)
Catalogue numberZX-005488
CAS number482577-59-3
Other CAS numbers137863-89-9
IUPAC namemethyl (2S)-2-[[4-(2-cyanophenyl)phenyl]methylamino]-3-methylbutanoate;hydrochloride
Molecular formulaC20H23ClN2O2
Molar mass358.9 g/mol
Exact mass358.1448
GradeReference Standard
Physical formSolid
H-bond donors / acceptors2 / 4
Topological polar surface area62.1 Ų
HS code38229090
InChIKeyAZQXUWUZQLZNIM-FYZYNONXSA-N
SMILESCC(C)[C@@H](C(=O)OC)NCC1=CC=C(C=C1)C2=CC=CC=C2C#N.Cl
PubChem CID16744793
SynonymsMethyl ((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)-L-valinate Hydrochloride, Valsartan Cyano Desvaleryl Methyl Ester, N-[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]-L-valine Methyl Ester Hydrochloride, N-(2'-Cyanobiphenyl-4-ylmethyl)-L-valine Methyl Ester Hydrochloride, N-[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]-L-valine methyl ester hydrochloride (1:1), N-(2-Cyanobiphenyl-4-ylmethyl)-L-valine Methyl Ester Hydrochloride, N-[(2'-cyanobiphenyl-4-yl)methyl]-(L)-valine methyl ester hydrochloride, (S)-Methyl 2-(((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)amino)-3-methylbutanoate HCl, Valsartan Impurity 56 HCl, N-(2'-Cyanobiphenyl-4-ylMethyl)-L-valine Methyl Ester HCl, N-[(2'-cyanobiphenyl-4-yl) methyl]-(L)-valine methyl ester hydrochloride

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS07 Irritant or harmful
Irritant or harmful

Signal word Warning

  • H302+H312+H332Harmful if swallowed, in contact with skin or if inhaled
  • H302Harmful if swallowed
  • H312Harmful in contact with skin
  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H332Harmful if inhaled

Precautionary statements P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P321, P330, P332 + P317, P337 + P317, P362 + P364, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Valsartan Impurity 8 (Hydrochloride)
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request
250 mgQuoted on request
500 mgQuoted on request
1 gQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Valsartan Impurity 8 (Hydrochloride)

Which CAS number identifies Valsartan Impurity 8 (Hydrochloride)?
Valsartan Impurity 8 (Hydrochloride) is registered under CAS 482577-59-3. You may also see it listed as Methyl ((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)-L-valinate Hydrochloride, Valsartan Cyano Desvaleryl Methyl Ester, N-[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]-L-valine Methyl Ester Hydrochloride. Our catalogue number for this item is ZX-005488.
What are the formula and molar mass of Valsartan Impurity 8 (Hydrochloride)?
For Valsartan Impurity 8 (Hydrochloride), its formula is C20H23ClN2O2 and its molar mass is 358.9 g/mol. InChIKey AZQXUWUZQLZNIM-FYZYNONXSA-N lets you match it in any structure database.
How is Valsartan Impurity 8 (Hydrochloride) used in pharmaceutical QC?
Valsartan Impurity 8 (Hydrochloride) is a characterised reference material linked to Valsartan. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Valsartan Impurity 8 (Hydrochloride)?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Valsartan Impurity 8 (Hydrochloride)?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Valsartan Impurity 8 (Hydrochloride) to my country?
Yes. Because Valsartan Impurity 8 (Hydrochloride) is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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