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API Impurities

Amitriptyline

Reference StandardAvailable on request

Order Amitriptyline (CAS 50-48-6) online at Zemixal. Lab and bulk packs, batch COA, fast global delivery. Quotes within one business day.

Pack sizes
Amitriptyline chemical structure
CAS number50-48-6
FormulaC20H23N
Molar mass277.4 g/mol
Physical formSolid
HS code38229090
InChIKeyKRMDCWKBEZIMAB-UHFFFAOYSA-N
IUPAC nameN,N-dimethyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)propan-1-amine

About Amitriptyline

Amitriptyline belongs to the Nortriptyline reference-standard family in the Zemixal catalogue. For your records (Reference Standard), the material is defined by CAS 50-48-6, formula C20H23N and molar mass 277.4 g/mol. It is handled as a solid.

Typical applications

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Storage and safety notes

It carries the GHS signal word Danger (H301+H311+H331, H301, H302 and H311), so wear gloves and eye protection and work with good ventilation.

Order it in 10 mg, 25 mg, 50 mg and 100 mg packs or ask for a bulk quotation. You receive a certificate of analysis with characterisation data with each order. Request pricing online and we confirm availability, documentation and freight to your country.

Reference standards for Nortriptyline

See every impurity, metabolite and related compound we list for this API.

Nortriptyline standards

Typical uses

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Applications

Specifications and identifiers

Specifications of Amitriptyline
Product nameAmitriptyline
Catalogue numberZX-033953
CAS number50-48-6
IUPAC nameN,N-dimethyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)propan-1-amine
Molecular formulaC20H23N
Molar mass277.4 g/mol
Exact mass277.183
GradeReference Standard
Physical formSolid
XLogP35
H-bond donors / acceptors0 / 1
Topological polar surface area3.2 Ų
HS code38229090
InChIKeyKRMDCWKBEZIMAB-UHFFFAOYSA-N
SMILESCN(C)CCC=C1C2=CC=CC=C2CCC3=CC=CC=C31
PubChem CID2160
SynonymsAmitriptylin, Damitriptyline, Triptanol, Flavyl, Proheptadiene, Triptisol, Amitryptiline, Tryptanol, Triptilin, Laroxyl, Amytriptylin, Amitryptyline

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS05 Corrosive
Corrosive
GHS06 Acute toxicity
Acute toxicity
GHS07 Irritant or harmful
Irritant or harmful
GHS08 Health hazard
Health hazard
GHS09 Hazardous to the environment
Hazardous to the environment

Signal word Danger

  • H301+H311+H331Toxic if swallowed, in contact with skin or if inhaled
  • H301Toxic if swallowed
  • H302Harmful if swallowed
  • H311Toxic in contact with skin
  • H318Causes serious eye damage
  • H331Toxic if inhaled
  • H361Suspected of damaging fertility or the unborn child
  • H410Very toxic to aquatic life with long lasting effects

Precautionary statements P203, P261, P262, P264, P264 + P265, P270, P271, P273, P280, P301 + P316, P301 + P317, P302 + P352, P304 + P340, P305 + P354 + P338, P316, P317, P318, P321, P330, P361 + P364, P391, P403 + P233, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Amitriptyline
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Amitriptyline

Which CAS number identifies Amitriptyline?
Amitriptyline is registered under CAS 50-48-6. You may also see it listed as Amitriptylin, Damitriptyline, Triptanol. Our catalogue number for this item is ZX-033953.
What are the formula and molar mass of Amitriptyline?
For Amitriptyline, its formula is C20H23N and its molar mass is 277.4 g/mol. The systematic (IUPAC) name is N,N-dimethyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)propan-1-amine. InChIKey KRMDCWKBEZIMAB-UHFFFAOYSA-N lets you match it in any structure database.
How is Amitriptyline used in pharmaceutical QC?
Amitriptyline is a characterised reference material linked to Nortriptyline. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Amitriptyline?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Amitriptyline?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Amitriptyline to my country?
Yes. Because Amitriptyline is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

More Nortriptyline standards

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