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API Impurities

Pyr-His-Trp-Ser-Tyr-OH

Reference StandardAvailable on request

Order Pyr-His-Trp-Ser-Tyr-OH (CAS 52434-75-0) online at Zemixal. Request a quote with price, lead time and documents. Part of our API Impurities range.

Pack sizes
Pyr-His-Trp-Ser-Tyr-OH chemical structure
CAS number52434-75-0
FormulaC34H38N8O9
Molar mass702.7 g/mol
Physical formSolid
HS code38229090
InChIKeyVVBDLEHCIKUJSA-XLIKFSOKSA-N
IUPAC name(2S)-2-[[(2S)-3-hydroxy-2-[[(2S)-2-[[(2S)-3-(1H-imidazol-5-yl)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]-3-(4-hydroxyphenyl)propanoic acid

About Pyr-His-Trp-Ser-Tyr-OH

Zemixal lists Pyr-His-Trp-Ser-Tyr-OH for laboratories that identify, quantify or control Leuprolide and its related substances. For your records (Reference Standard), the material is defined by CAS 52434-75-0, formula C34H38N8O9 and molar mass 702.7 g/mol. It is handled as a solid.

Where it is used

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Storage and safety notes

Hazard communication follows GHS (Danger: H360). Our SDS lists exposure controls and first-aid measures.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and custom quantities are quoted on request. Every shipment includes a certificate of analysis with characterisation data. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.

Reference standards for Leuprolide

See every impurity, metabolite and related compound we list for this API.

Leuprolide standards

Typical uses

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Applications

Specifications and identifiers

Specifications of Pyr-His-Trp-Ser-Tyr-OH
Product namePyr-His-Trp-Ser-Tyr-OH
Catalogue numberZX-033705
CAS number52434-75-0
IUPAC name(2S)-2-[[(2S)-3-hydroxy-2-[[(2S)-2-[[(2S)-3-(1H-imidazol-5-yl)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]-3-(4-hydroxyphenyl)propanoic acid
Molecular formulaC34H38N8O9
Molar mass702.7 g/mol
Exact mass702.2762
GradeReference Standard
Physical formSolid
XLogP3-0.1
H-bond donors / acceptors10 / 10
Topological polar surface area268 Ų
HS code38229090
InChIKeyVVBDLEHCIKUJSA-XLIKFSOKSA-N
SMILESC1CC(=O)N[C@@H]1C(=O)N[C@@H](CC2=CN=CN2)C(=O)N[C@@H](CC3=CNC4=CC=CC=C43)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC5=CC=C(C=C5)O)C(=O)O
PubChem CID13190525
SynonymsLHRH (1-5) (free acid), LHRH (1-5) (free acid) trifluoroacetate salt, pGlu-His-Trp-Ser-Tyr, L-Tyrosine, 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-, Pyr-His-Trp-Ser-Tyr-OH trifluoroacetate salt

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS08 Health hazard
Health hazard

Signal word Danger

  • H360May damage fertility or the unborn child

Precautionary statements P203, P280, P318, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Pyr-His-Trp-Ser-Tyr-OH
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Pyr-His-Trp-Ser-Tyr-OH

Which CAS number identifies Pyr-His-Trp-Ser-Tyr-OH?
Pyr-His-Trp-Ser-Tyr-OH is registered under CAS 52434-75-0. You may also see it listed as LHRH (1-5) (free acid), LHRH (1-5) (free acid) trifluoroacetate salt, pGlu-His-Trp-Ser-Tyr. Our catalogue number for this item is ZX-033705.
What are the formula and molar mass of Pyr-His-Trp-Ser-Tyr-OH?
For Pyr-His-Trp-Ser-Tyr-OH, its formula is C34H38N8O9 and its molar mass is 702.7 g/mol. InChIKey VVBDLEHCIKUJSA-XLIKFSOKSA-N lets you match it in any structure database.
How is Pyr-His-Trp-Ser-Tyr-OH used in pharmaceutical QC?
Pyr-His-Trp-Ser-Tyr-OH is a characterised reference material linked to Leuprolide. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Pyr-His-Trp-Ser-Tyr-OH?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Pyr-His-Trp-Ser-Tyr-OH?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Pyr-His-Trp-Ser-Tyr-OH to my country?
Yes. Because Pyr-His-Trp-Ser-Tyr-OH is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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