11α,17,21-Trihydroxy-16α-methylpregna-1,4-diene-3,20-dione

Name: 11α,17,21-Trihydroxy-16α-methylpregna-1,4-diene-3,20-dione
Brand: Zemixal
SKU: ZX-036457

Reference StandardAvailable on request

Buy 11α,17,21-Trihydroxy-16α-methylpregna-1,4-diene-3,20-dione (CAS 78761-59-8) from Zemixal. Lab and bulk packs, batch COA, fast global delivery.

Pack sizes

11α,17,21-Trihydroxy-16α-methylpregna-1,4-diene-3,20-dione chemical structure

CAS number78761-59-8

FormulaC₂₂H₃₀O₅

Molar mass374.5 g/mol

Physical formSolid

HS code38229090

InChIKeyWNYLPFCKNQAAMB-JPDWDDBRSA-N

IUPAC name(8S,9S,10R,11R,13S,14S,16R,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one

About 11α,17,21-Trihydroxy-16α-methylpregna-1,4-diene-3,20-dione

Zemixal lists 11α,17,21-Trihydroxy-16α-methylpregna-1,4-diene-3,20-dione for laboratories that identify, quantify or control Dexamethasone and its related substances. Identity at a glance (Reference Standard): CAS 78761-59-8, formula C22H30O5 and molar mass 374.5 g/mol. It is handled as a solid.

Use cases we see most often

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Handling and storage

It carries the GHS signal word Danger (H360 and H373), so wear gloves and eye protection and work with good ventilation.

Available as 10 mg, 25 mg, 50 mg and 100 mg. Larger or split packs can be arranged. Every shipment includes a certificate of analysis with characterisation data. Request pricing online and we confirm availability, documentation and freight to your country.

Reference standards for Dexamethasone

See every impurity, metabolite and related compound we list for this API.

Dexamethasone standards

Typical uses

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Applications

Pharmaceutical Manufacturing and QC Research Labs and Universities

Specifications and identifiers

Specifications of 11α,17,21-Trihydroxy-16α-methylpregna-1,4-diene-3,20-dione
Product name	11α,17,21-Trihydroxy-16α-methylpregna-1,4-diene-3,20-dione
Catalogue number	ZX-036457
CAS number	78761-59-8
IUPAC name	(8S,9S,10R,11R,13S,14S,16R,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
Molecular formula	C₂₂H₃₀O₅
Molar mass	374.5 g/mol
Exact mass	374.2093
Grade	Reference Standard
Physical form	Solid
XLogP3	2.1
H-bond donors / acceptors	3 / 5
Topological polar surface area	94.8 Å²
HS code	38229090
InChIKey	WNYLPFCKNQAAMB-JPDWDDBRSA-N
SMILES	C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@H]3[C@@H](C[C@@]2([C@]1(C(=O)CO)O)C)O)C
PubChem CID	11314822
Synonyms	11alpha,17alpha,21-Trihydroxy-16alpha-methyl-1,4-pregnadiene-3,20-dione, 11alpha,17,21-Trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione, (11alpha,16alpha)-11,17,21-Trihydroxy-16-methylpregna-1,4-diene-3,20-dione, 11a,17a,21-Trihydroxy-16a-methyl-1,4-pregnadiene-3,20-dione, 11I+/-,17I+/-,21-Trihydroxy-16I+/--methyl-1,4-pregnadiene-3,20-dione, (11OE+/-,16OE+/-)-11,17,21-Trihydroxy-16-methylpregna-1,4-diene-3,20-dione, 1OE+/-,17OE+/-,21-Trihydroxy-16OE+/--methyl-1,4-pregnadiene-3,20-dione

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

Health hazard

Signal word Danger

H360May damage fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements P203, P260, P280, P318, P319, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of 11α,17,21-Trihydroxy-16α-methylpregna-1,4-diene-3,20-dione
10 mg	Quoted on request
25 mg	Quoted on request
50 mg	Quoted on request
100 mg	Quoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about 11α,17,21-Trihydroxy-16α-methylpregna-1,4-diene-3,20-dione

Which CAS number identifies 11α,17,21-Trihydroxy-16α-methylpregna-1,4-diene-3,20-dione?

11α,17,21-Trihydroxy-16α-methylpregna-1,4-diene-3,20-dione is registered under CAS 78761-59-8. You may also see it listed as 11alpha,17alpha,21-Trihydroxy-16alpha-methyl-1,4-pregnadiene-3,20-dione, 11alpha,17,21-Trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione, (11alpha,16alpha)-11,17,21-Trihydroxy-16-methylpregna-1,4-diene-3,20-dione. Our catalogue number for this item is ZX-036457.

What are the formula and molar mass of 11α,17,21-Trihydroxy-16α-methylpregna-1,4-diene-3,20-dione?

For 11α,17,21-Trihydroxy-16α-methylpregna-1,4-diene-3,20-dione, its formula is C22H30O5 and its molar mass is 374.5 g/mol. The systematic (IUPAC) name is (8S,9S,10R,11R,13S,14S,16R,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one. InChIKey WNYLPFCKNQAAMB-JPDWDDBRSA-N lets you match it in any structure database.

How is 11α,17,21-Trihydroxy-16α-methylpregna-1,4-diene-3,20-dione used in pharmaceutical QC?

11α,17,21-Trihydroxy-16α-methylpregna-1,4-diene-3,20-dione is a characterised reference material linked to Dexamethasone. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.

What grade and pack sizes are available for 11α,17,21-Trihydroxy-16α-methylpregna-1,4-diene-3,20-dione?

This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.

Which documents come with 11α,17,21-Trihydroxy-16α-methylpregna-1,4-diene-3,20-dione?

Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.

Can Zemixal ship 11α,17,21-Trihydroxy-16α-methylpregna-1,4-diene-3,20-dione to my country?

Yes. Because 11α,17,21-Trihydroxy-16α-methylpregna-1,4-diene-3,20-dione is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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