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API Impurities

21-Carboxy Dexamethasone

Reference StandardAvailable on request

Buy 21-Carboxy Dexamethasone (CAS 84449-15-0) from Zemixal: C22H27FO6, COA and SDS with every lot, worldwide shipping. Catalogue no. ZX-021380.

Pack sizes
21-Carboxy Dexamethasone chemical structure
CAS number84449-15-0
FormulaC22H27FO6
Molar mass406.4 g/mol
Physical formSolid
HS code38229090
InChIKeyHJQXVITYEPBWQP-LODYHXIVSA-N
IUPAC name2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoacetic acid

About 21-Carboxy Dexamethasone

21-Carboxy Dexamethasone belongs to the Dexamethasone reference-standard family in the Zemixal catalogue. Key data (Reference Standard): CAS 84449-15-0, formula C22H27FO6 and molar mass 406.4 g/mol. It is handled as a solid.

Where it is used

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Safe handling

Classified under GHS with signal word Warning and hazard statements H361 and H373. Read the SDS before first use.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and custom quantities are quoted on request. You receive a certificate of analysis with characterisation data with each order. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.

Reference standards for Dexamethasone

See every impurity, metabolite and related compound we list for this API.

Dexamethasone standards

Typical uses

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Applications

Specifications and identifiers

Specifications of 21-Carboxy Dexamethasone
Product name21-Carboxy Dexamethasone
Catalogue numberZX-021380
CAS number84449-15-0
IUPAC name2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoacetic acid
Molecular formulaC22H27FO6
Molar mass406.4 g/mol
Exact mass406.1792
GradeReference Standard
Physical formSolid
XLogP32.4
H-bond donors / acceptors3 / 7
Topological polar surface area112 Ų
HS code38229090
InChIKeyHJQXVITYEPBWQP-LODYHXIVSA-N
SMILESC[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)C(=O)O)O)C)O)F)C
PubChem CID67930120
SynonymsDexamethasone Glyoxal Analog, (11beta,16alpha)-9-Fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-oic acid, (11ss,16a)-9-Fluoro-11,17-dihydroxy-16-methyl-3,20-dioxo-pregna-1,4-dien-21-oic acid, Dexamethasone-21-oic acid

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS08 Health hazard
Health hazard

Signal word Warning

  • H361Suspected of damaging fertility or the unborn child
  • H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements P203, P260, P280, P318, P319, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of 21-Carboxy Dexamethasone
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about 21-Carboxy Dexamethasone

Which CAS number identifies 21-Carboxy Dexamethasone?
21-Carboxy Dexamethasone is registered under CAS 84449-15-0. You may also see it listed as Dexamethasone Glyoxal Analog, (11beta,16alpha)-9-Fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-oic acid, (11ss,16a)-9-Fluoro-11,17-dihydroxy-16-methyl-3,20-dioxo-pregna-1,4-dien-21-oic acid. Our catalogue number for this item is ZX-021380.
What are the formula and molar mass of 21-Carboxy Dexamethasone?
For 21-Carboxy Dexamethasone, its formula is C22H27FO6 and its molar mass is 406.4 g/mol. InChIKey HJQXVITYEPBWQP-LODYHXIVSA-N lets you match it in any structure database.
How is 21-Carboxy Dexamethasone used in pharmaceutical QC?
21-Carboxy Dexamethasone is a characterised reference material linked to Dexamethasone. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for 21-Carboxy Dexamethasone?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with 21-Carboxy Dexamethasone?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship 21-Carboxy Dexamethasone to my country?
Yes. Because 21-Carboxy Dexamethasone is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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