N-(6-Chloro-5-methylpyridin-2-yl)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropane-1-carboxamide
- CAS
- 936727-68-3
- Formula
- C17H13ClF2N2O3
- MW
- 366.7 g/mol
ZX-030399
API Impurities
1-(2,2-Difluoro-benzo[1,3]dioxol-5-yl)-cyclopropanecarboxylic acid
Reference StandardAvailable on request
1-(2,2-Difluoro-benzo[1,3]dioxol-5-yl)-cyclopropanecarboxylic acid (CAS 862574-88-7) supplier Zemixal. Request a quote with price, lead time and documents.
![1-(2,2-Difluoro-benzo[1,3]dioxol-5-yl)-cyclopropanecarboxylic acid chemical structure](/media/structures/zx-IELWGOUPQRHXLS-UHFFFAOYSA-N.svg?v=2)
CAS number862574-88-7
FormulaC11H8F2O4
Molar mass242.17 g/mol
Physical formSolid
HS code38229090
InChIKeyIELWGOUPQRHXLS-UHFFFAOYSA-N
IUPAC name1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropane-1-carboxylic acid
About 1-(2,2-Difluoro-benzo[1,3]dioxol-5-yl)-cyclopropanecarboxylic acid
1-(2,2-Difluoro-benzo[1,3]dioxol-5-yl)-cyclopropanecarboxylic acid is supplied by Zemixal as a characterised reference material for Lumacaftor analysis. Key data (Reference Standard): CAS 862574-88-7, formula C11H8F2O4 and molar mass 242.17 g/mol. It is handled as a solid.
Use cases we see most often
- Analytical method development
- Method validation (AMV)
- QC release testing
- ANDA / DMF filings
Storage and safety notes
Hazard communication follows GHS (Warning: H302, H315, H319 and H335). Our SDS lists exposure controls and first-aid measures.
Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and custom quantities are quoted on request. Every shipment includes a certificate of analysis with characterisation data. Request pricing online and we confirm availability, documentation and freight to your country.
Reference standards for Lumacaftor
See every impurity, metabolite and related compound we list for this API.
Lumacaftor standardsTypical uses
- Analytical method development
- Method validation (AMV)
- QC release testing
- ANDA / DMF filings
Applications
Specifications and identifiers
| Product name | 1-(2,2-Difluoro-benzo[1,3]dioxol-5-yl)-cyclopropanecarboxylic acid |
|---|---|
| Catalogue number | ZX-035002 |
| CAS number | 862574-88-7 |
| IUPAC name | 1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropane-1-carboxylic acid |
| Molecular formula | C11H8F2O4 |
| Molar mass | 242.17 g/mol |
| Exact mass | 242.0391 |
| Grade | Reference Standard |
| Physical form | Solid |
| XLogP3 | 2.3 |
| H-bond donors / acceptors | 1 / 6 |
| Topological polar surface area | 55.8 Ų |
| HS code | 38229090 |
| InChIKey | IELWGOUPQRHXLS-UHFFFAOYSA-N |
| SMILES | C1CC1(C2=CC3=C(C=C2)OC(O3)(F)F)C(=O)O |
| PubChem CID | 44206103 |
| Synonyms | 1-(2,2-Difluoro-1,3-benzodioxol-5-yl)cyclopropanecarboxylic acid, 1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropane-1-carboxylic acid, 1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropane-1-carboxylic acid, 1-(2,2-Difluorobenzo(d)(1,3)dioxol-5-yl)cyclopropanecarboxylic acid, Cyclopropanecarboxylic acid, 1-(2,2-difluoro-1,3-benzodioxol-5-yl)-, CS-M2012, 1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cy |
Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.
Safety and GHS hazards
Signal word Warning
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501
Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.
Pack sizes
| 10 mg | Quoted on request | |
| 25 mg | Quoted on request | |
| 50 mg | Quoted on request | |
| 100 mg | Quoted on request |
Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.
Questions about 1-(2,2-Difluoro-benzo[1,3]dioxol-5-yl)-cyclopropanecarboxylic acid
Which CAS number identifies 1-(2,2-Difluoro-benzo[1,3]dioxol-5-yl)-cyclopropanecarboxylic acid?
1-(2,2-Difluoro-benzo[1,3]dioxol-5-yl)-cyclopropanecarboxylic acid is registered under CAS 862574-88-7. You may also see it listed as 1-(2,2-Difluoro-1,3-benzodioxol-5-yl)cyclopropanecarboxylic acid, 1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropane-1-carboxylic acid, 1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropane-1-carboxylic acid. Our catalogue number for this item is ZX-035002.
What are the formula and molar mass of 1-(2,2-Difluoro-benzo[1,3]dioxol-5-yl)-cyclopropanecarboxylic acid?
For 1-(2,2-Difluoro-benzo[1,3]dioxol-5-yl)-cyclopropanecarboxylic acid, its formula is C11H8F2O4 and its molar mass is 242.17 g/mol. The systematic (IUPAC) name is 1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropane-1-carboxylic acid. InChIKey IELWGOUPQRHXLS-UHFFFAOYSA-N lets you match it in any structure database.
How is 1-(2,2-Difluoro-benzo[1,3]dioxol-5-yl)-cyclopropanecarboxylic acid used in pharmaceutical QC?
1-(2,2-Difluoro-benzo[1,3]dioxol-5-yl)-cyclopropanecarboxylic acid is a characterised reference material linked to Lumacaftor. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for 1-(2,2-Difluoro-benzo[1,3]dioxol-5-yl)-cyclopropanecarboxylic acid?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with 1-(2,2-Difluoro-benzo[1,3]dioxol-5-yl)-cyclopropanecarboxylic acid?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship 1-(2,2-Difluoro-benzo[1,3]dioxol-5-yl)-cyclopropanecarboxylic acid to my country?
Yes. Because 1-(2,2-Difluoro-benzo[1,3]dioxol-5-yl)-cyclopropanecarboxylic acid is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.
More Lumacaftor standards
More in API Impurities
Have a list of compounds to price?
Paste up to 200 CAS numbers into Bulk CAS lookup, or send one enquiry for everything in your quote list. We reply with price, lead time and documents.