N-(6-Chloro-5-methylpyridin-2-yl)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropane-1-carboxamide
- CAS
- 936727-68-3
- Formula
- C17H13ClF2N2O3
- MW
- 366.7 g/mol
ZX-030399
API Reference Standards
Lumacaftor
Reference StandardAvailable on request
Buy Lumacaftor (CAS 936727-05-8) from Zemixal: C24H18F2N2O5, COA and SDS with every lot, worldwide shipping. Packs from 10 mg.
CAS number936727-05-8
FormulaC24H18F2N2O5
Molar mass452.4 g/mol
Physical formSolid
HS code38229090
InChIKeyUFSKUSARDNFIRC-UHFFFAOYSA-N
IUPAC name3-[6-[[1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropanecarbonyl]amino]-3-methyl-2-pyridinyl]benzoic acid
About Lumacaftor
Zemixal lists Lumacaftor for laboratories that identify, quantify or control Lumacaftor and its related substances. Identity at a glance (Reference Standard): CAS 936727-05-8, formula C24H18F2N2O5 and molar mass 452.4 g/mol. It is handled as a solid.
Use cases we see most often
- Identification & assay
- Method development & validation
- QC reference material
Safe handling
Hazard communication follows GHS (Danger: H301, H302, H312 and H315). Our SDS lists exposure controls and first-aid measures.
Order it in 10 mg, 25 mg, 50 mg and 100 mg packs or ask for a bulk quotation. Every shipment includes a certificate of analysis with characterisation data. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.
Reference standards for Lumacaftor
See every impurity, metabolite and related compound we list for this API.
Lumacaftor standardsTypical uses
- Identification & assay
- Method development & validation
- QC reference material
Applications
Specifications and identifiers
| Product name | Lumacaftor |
|---|---|
| Catalogue number | ZX-025463 |
| CAS number | 936727-05-8 |
| IUPAC name | 3-[6-[[1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropanecarbonyl]amino]-3-methyl-2-pyridinyl]benzoic acid |
| Molecular formula | C24H18F2N2O5 |
| Molar mass | 452.4 g/mol |
| Exact mass | 452.1184 |
| Grade | Reference Standard |
| Physical form | Solid |
| XLogP3 | 4.4 |
| H-bond donors / acceptors | 2 / 8 |
| Topological polar surface area | 97.8 Ų |
| HS code | 38229090 |
| InChIKey | UFSKUSARDNFIRC-UHFFFAOYSA-N |
| SMILES | CC1=C(N=C(C=C1)NC(=O)C2(CC2)C3=CC4=C(C=C3)OC(O4)(F)F)C5=CC(=CC=C5)C(=O)O |
| PubChem CID | 16678941 |
| Synonyms | VX-809, VX 809, VX-809 (Lumacaftor), Lumacaftor(vx-809vx809), Lumacaftor (USAN), Lumacaftor (VX-809), EX-A178 |
Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.
Safety and GHS hazards
Signal word Danger
- H301Toxic if swallowed
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H318Causes serious eye damage
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H360May damage fertility or the unborn child
- H372Causes damage to organs through prolonged or repeated exposure
Precautionary statements P203, P260, P261, P264, P264 + P265, P270, P271, P280, P301 + P316, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P305 + P354 + P338, P317, P318, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405
Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.
Pack sizes
| 10 mg | Quoted on request | |
| 25 mg | Quoted on request | |
| 50 mg | Quoted on request | |
| 100 mg | Quoted on request |
Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.
Questions about Lumacaftor
Which CAS number identifies Lumacaftor?
Lumacaftor is registered under CAS 936727-05-8. You may also see it listed as VX-809, VX 809, VX-809 (Lumacaftor). Our catalogue number for this item is ZX-025463.
What are the formula and molar mass of Lumacaftor?
For Lumacaftor, its formula is C24H18F2N2O5 and its molar mass is 452.4 g/mol. The systematic (IUPAC) name is 3-[6-[[1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropanecarbonyl]amino]-3-methyl-2-pyridinyl]benzoic acid. InChIKey UFSKUSARDNFIRC-UHFFFAOYSA-N lets you match it in any structure database.
How is Lumacaftor used in pharmaceutical QC?
Lumacaftor is a characterised reference material linked to Lumacaftor. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Lumacaftor?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Lumacaftor?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Lumacaftor to my country?
Yes. Because Lumacaftor is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.
More Lumacaftor standards
More in API Reference Standards
1-(2,2-Difluoro-benzo[1,3]dioxol-5-yl)-cyclopropanecarboxylic acid
- CAS
- 862574-88-7
- Formula
- C11H8F2O4
- MW
- 242.17 g/mol
ZX-035002
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