1-Chloro-4-isocyanato-2-(trifluoromethyl)benzene

Name: 1-Chloro-4-isocyanato-2-(trifluoromethyl)benzene
Brand: Zemixal
SKU: ZX-034537

Reference StandardAvailable on request

Buy 1-Chloro-4-isocyanato-2-(trifluoromethyl)benzene (CAS 327-78-6) from Zemixal: C8H3ClF3NO, COA and SDS with every lot, worldwide shipping.

Pack sizes

1-Chloro-4-isocyanato-2-(trifluoromethyl)benzene chemical structure

CAS number327-78-6

FormulaC₈H₃ClF₃NO

Molar mass221.56 g/mol

Physical formSolid

HS code38229090

InChIKeyNBJZEUQTGLSUOB-UHFFFAOYSA-N

IUPAC name1-chloro-4-isocyanato-2-(trifluoromethyl)benzene

About 1-Chloro-4-isocyanato-2-(trifluoromethyl)benzene

1-Chloro-4-isocyanato-2-(trifluoromethyl)benzene belongs to the Sorafenib reference-standard family in the Zemixal catalogue. For your records (Reference Standard), the material is defined by CAS 327-78-6, formula C8H3ClF3NO and molar mass 221.56 g/mol. It is handled as a solid.

Use cases we see most often

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Storage and safety notes

Hazard communication follows GHS (Danger: H302, H312, H315 and H319). Our SDS lists exposure controls and first-aid measures.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and custom quantities are quoted on request. You receive a certificate of analysis with characterisation data with each order. Add it to your quote list and our team replies with price, lead time and shipping options within one business day.

Reference standards for Sorafenib

See every impurity, metabolite and related compound we list for this API.

Sorafenib standards

Typical uses

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Applications

Pharmaceutical Manufacturing and QC Research Labs and Universities

Specifications and identifiers

Specifications of 1-Chloro-4-isocyanato-2-(trifluoromethyl)benzene
Product name	1-Chloro-4-isocyanato-2-(trifluoromethyl)benzene
Catalogue number	ZX-034537
CAS number	327-78-6
IUPAC name	1-chloro-4-isocyanato-2-(trifluoromethyl)benzene
Molecular formula	C₈H₃ClF₃NO
Molar mass	221.56 g/mol
Exact mass	220.9855
Grade	Reference Standard
Physical form	Solid
XLogP3	5
H-bond donors / acceptors	0 / 5
Topological polar surface area	29.4 Å²
HS code	38229090
InChIKey	NBJZEUQTGLSUOB-UHFFFAOYSA-N
SMILES	C1=CC(=C(C=C1N=C=O)C(F)(F)F)Cl
PubChem CID	2733265
Synonyms	4-Chloro-3-(trifluoromethyl)phenyl Isocyanate, 4-Chloro-3-(trifluoromethyl)phenylisocyanate, 4-chloro-3-(trifluoromethyl)benzenisocyanate, CS-M2757, 4-chloro-3-trifluoromethyphenylisocyanate, 3-trifluoromethyl-4-chlorophenylisocyanate, 4-chloro-3-trifluoromethylphenylisocyanate, 4chloro-3-trifluoromethylphenyl isocyanate, 3-trifluoromethyl- 4-chlorophenylisocyanate, 3-trifluoromethyl-4-chloro-phenylisocyanate, 3-trifluoromethyl-4-chlorophenyl isocyanate

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

Irritant or harmful

Health hazard

Signal word Danger

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335May cause respiratory irritation

Precautionary statements P233, P260, P261, P264, P264 + P265, P270, P271, P280, P284, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P342 + P316, P362 + P364, P403, P403 + P233, P405

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of 1-Chloro-4-isocyanato-2-(trifluoromethyl)benzene
10 mg	Quoted on request
25 mg	Quoted on request
50 mg	Quoted on request
100 mg	Quoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about 1-Chloro-4-isocyanato-2-(trifluoromethyl)benzene

Which CAS number identifies 1-Chloro-4-isocyanato-2-(trifluoromethyl)benzene?

1-Chloro-4-isocyanato-2-(trifluoromethyl)benzene is registered under CAS 327-78-6. You may also see it listed as 4-Chloro-3-(trifluoromethyl)phenyl Isocyanate, 4-Chloro-3-(trifluoromethyl)phenylisocyanate, 4-chloro-3-(trifluoromethyl)benzenisocyanate. Our catalogue number for this item is ZX-034537.

What are the formula and molar mass of 1-Chloro-4-isocyanato-2-(trifluoromethyl)benzene?

For 1-Chloro-4-isocyanato-2-(trifluoromethyl)benzene, its formula is C8H3ClF3NO and its molar mass is 221.56 g/mol. The systematic (IUPAC) name is 1-chloro-4-isocyanato-2-(trifluoromethyl)benzene. InChIKey NBJZEUQTGLSUOB-UHFFFAOYSA-N lets you match it in any structure database.

How is 1-Chloro-4-isocyanato-2-(trifluoromethyl)benzene used in pharmaceutical QC?

1-Chloro-4-isocyanato-2-(trifluoromethyl)benzene is a characterised reference material linked to Sorafenib. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.

What grade and pack sizes are available for 1-Chloro-4-isocyanato-2-(trifluoromethyl)benzene?

This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.

Which documents come with 1-Chloro-4-isocyanato-2-(trifluoromethyl)benzene?

Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.

Can Zemixal ship 1-Chloro-4-isocyanato-2-(trifluoromethyl)benzene to my country?

Yes. Because 1-Chloro-4-isocyanato-2-(trifluoromethyl)benzene is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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