Impurity reference standards
Sorafenib impurity standards
This page brings together 46 Sorafenib related compounds that analytical teams use to identify, quantify and control impurities in the active ingredient and the finished dosage form. The range includes 1 pharmacopoeial impurity, 3 isotope-labelled standards, 3 metabolites or hydroxylated analogues and 1 degradation product.
46reference materials
1pharmacopoeial
3isotope labelled
3metabolites
Each lot ships with a certificate of analysis, and characterisation data such as 1H-NMR, mass spectrum and HPLC purity can be shared before you order. Typical uses are method development and validation, relative response factor work, forced degradation studies and the impurity sections of ANDA, DMF or CEP filings.
By impurity type
Pharmacopoeial1EP, USP, BP or JP named impurities
Isotope labelled3Deuterated, 13C or 15N internal standards
Metabolites3Hydroxy, desmethyl and conjugated forms
Degradants1N-oxides, dimers, lactones and breakdown products
Counts are based on product names. One compound can fall into more than one type.
All Sorafenib reference materials
1–46 of 46 standards
1 Chloro 2 isocyanato 4 trifluoromethyl benzene
- CAS
- 50528-86-4
- Formula
- C8H3ClF3NO
- MW
- 221.56 g/mol
ZX-036198
1-(4-Chloro-3-trifluoromethylphenyl)-3-(4-hydroxyphenyl)urea
- CAS
- 1129683-83-5
- Formula
- C14H10ClF3N2O2
- MW
- 330.69 g/mol
ZX-031323
2-Chloro-1-isocyanato-3-(trifluoromethyl)benzene
- CAS
- 88330-63-6
- Formula
- C8H3ClF3NO
- MW
- 221.56 g/mol
ZX-031524
3-Chloro-5-trifluoromethylphenylsulfonyl chloride
- CAS
- 875167-01-4
- Formula
- C7H3Cl2F3O2S
- MW
- 279.06 g/mol
ZX-047950
4-Chloro-3-(trifluoromethyl)benzenesulfonyl chloride
- CAS
- 32333-53-2
- Formula
- C7H3Cl2F3O2S
- MW
- 279.06 g/mol
ZX-040520
4-Chloro-N-methylpyridine-2-carboxamide Hydrochloride
- CAS
- 882167-77-3
- Formula
- C7H8Cl2N2O
- MW
- 207.05 g/mol
ZX-042511
Methyl (4-chloro-3-trifluoromethylphenyl)carbamate
- CAS
- 19448-54-5
- Formula
- C9H7ClF3NO2
- MW
- 253.6 g/mol
ZX-032555
Phenyl (4-chloro-3-(trifluoromethyl)phenyl)carbamate
- CAS
- 871555-75-8
- Formula
- C14H9ClF3NO2
- MW
- 315.67 g/mol
ZX-032554
Questions
Sorafenib impurities, answered
What Sorafenib reference materials are available?
The catalogue currently lists 46 compounds for Sorafenib, including 1 pharmacopoeial impurity, 3 isotope-labelled standards, 3 metabolites or hydroxylated analogues and 1 degradation product. Each product page shows the CAS number where one is assigned, the structure, formula and molecular weight.
What documents come with a Sorafenib impurity standard?
A certificate of analysis travels with every lot. On request we share the characterisation set, usually 1H-NMR, mass spectrum, HPLC purity and IR, and for some materials TGA or water content. Ask for the data before ordering if your QA team needs to review it.
Can Zemixal make a Sorafenib impurity that is not listed?
Often yes. Send the structure, name or CAS number with the quantity you need and our sourcing team checks custom synthesis options, usually from 10 mg up to gram scale, with a quoted lead time.
Are isotope-labelled Sorafenib standards available?
Yes. 3 stable-isotope labelled compounds are listed, suitable as internal standards for LC-MS bioanalysis and trace impurity quantitation.