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API Impurities

10-Formyl-7,8-dihydro Folic Acid

Reference StandardAvailable on request

10-Formyl-7,8-dihydro Folic Acid (CAS 28459-40-7) supplier Zemixal: C20H21N7O7, COA and SDS with every lot, worldwide shipping.

Pack sizes
10-Formyl-7,8-dihydro Folic Acid chemical structure
CAS number28459-40-7
FormulaC20H21N7O7
Molar mass471.4 g/mol
Physical formSolid
HS code38229090
InChIKeyUXFQDXABPXWSTK-ZDUSSCGKSA-N
IUPAC name(2S)-2-[[4-[(2-amino-4-oxo-7,8-dihydro-3H-pteridin-6-yl)methyl-formylamino]benzoyl]amino]pentanedioic acid

About 10-Formyl-7,8-dihydro Folic Acid

10-Formyl-7,8-dihydro Folic Acid is supplied by Zemixal as a characterised reference material for Levofolinate analysis. Identity at a glance (Reference Standard): CAS 28459-40-7, formula C20H21N7O7 and molar mass 471.4 g/mol. It is handled as a solid.

Use cases we see most often

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Safe handling

Hazard communication follows GHS (Danger: H317 and H334). Our SDS lists exposure controls and first-aid measures.

Available as 10 mg, 25 mg, 50 mg and 100 mg. Larger or split packs can be arranged. Every shipment includes a certificate of analysis with characterisation data. Add it to your quote list and our team replies with price, lead time and shipping options within one business day.

Reference standards for Levofolinate

See every impurity, metabolite and related compound we list for this API.

Levofolinate standards

Typical uses

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Applications

Specifications and identifiers

Specifications of 10-Formyl-7,8-dihydro Folic Acid
Product name10-Formyl-7,8-dihydro Folic Acid
Catalogue numberZX-027741
CAS number28459-40-7
IUPAC name(2S)-2-[[4-[(2-amino-4-oxo-7,8-dihydro-3H-pteridin-6-yl)methyl-formylamino]benzoyl]amino]pentanedioic acid
Molecular formulaC20H21N7O7
Molar mass471.4 g/mol
Exact mass471.1502
GradeReference Standard
Physical formSolid
XLogP3-1.5
H-bond donors / acceptors6 / 10
Topological polar surface area216 Ų
HS code38229090
InChIKeyUXFQDXABPXWSTK-ZDUSSCGKSA-N
SMILESC1C(=NC2=C(N1)N=C(NC2=O)N)CN(C=O)C3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O
PubChem CID135398690
Synonyms10-Formyldihydrofolate, 10-formyldihydrofolic acid, F-D folic acid, 10-formyl-7,8-dihydrofolate, N-(10-formyl-7,8-dihydropteroyl)-L-glutamate, 28459-40-7 free acid

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS08 Health hazard
Health hazard

Signal word Danger

  • H317May cause an allergic skin reaction
  • H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements P233, P260, P261, P271, P272, P280, P284, P302 + P352, P304 + P340, P321, P333 + P317, P342 + P316, P362 + P364, P403, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of 10-Formyl-7,8-dihydro Folic Acid
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about 10-Formyl-7,8-dihydro Folic Acid

Which CAS number identifies 10-Formyl-7,8-dihydro Folic Acid?
10-Formyl-7,8-dihydro Folic Acid is registered under CAS 28459-40-7. You may also see it listed as 10-Formyldihydrofolate, 10-formyldihydrofolic acid, F-D folic acid. Our catalogue number for this item is ZX-027741.
What are the formula and molar mass of 10-Formyl-7,8-dihydro Folic Acid?
For 10-Formyl-7,8-dihydro Folic Acid, its formula is C20H21N7O7 and its molar mass is 471.4 g/mol. The systematic (IUPAC) name is (2S)-2-[[4-[(2-amino-4-oxo-7,8-dihydro-3H-pteridin-6-yl)methyl-formylamino]benzoyl]amino]pentanedioic acid. InChIKey UXFQDXABPXWSTK-ZDUSSCGKSA-N lets you match it in any structure database.
How is 10-Formyl-7,8-dihydro Folic Acid used in pharmaceutical QC?
10-Formyl-7,8-dihydro Folic Acid is a characterised reference material linked to Levofolinate. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for 10-Formyl-7,8-dihydro Folic Acid?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with 10-Formyl-7,8-dihydro Folic Acid?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship 10-Formyl-7,8-dihydro Folic Acid to my country?
Yes. Because 10-Formyl-7,8-dihydro Folic Acid is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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