Dihydro Folic Acid

Name: Dihydro Folic Acid
Brand: Zemixal
SKU: ZX-023087

Reference StandardAvailable on request

Buy Dihydro Folic Acid (CAS 4033-27-6) from Zemixal: C19H21N7O6, COA and SDS with every lot, worldwide shipping. Part of our API Impurities range.

Pack sizes

CAS number4033-27-6

FormulaC₁₉H₂₁N₇O₆

Molar mass443.4 g/mol

Physical formSolid

HS code38229090

InChIKeyOZRNSSUDZOLUSN-LBPRGKRZSA-N

IUPAC name(2S)-2-[[4-[(2-amino-4-oxo-7,8-dihydro-3H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid

About Dihydro Folic Acid

Dihydro Folic Acid is supplied by Zemixal as a characterised reference material for Levofolinate analysis. Key data (Reference Standard): CAS 4033-27-6, formula C19H21N7O6 and molar mass 443.4 g/mol. It is handled as a solid.

Use cases we see most often

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Storage and safety notes

It carries the GHS signal word Warning (H315, H319 and H335), so wear gloves and eye protection and work with good ventilation.

Order it in 10 mg, 25 mg, 50 mg and 100 mg packs or ask for a bulk quotation. Each lot travels with a certificate of analysis with characterisation data. Request pricing online and we confirm availability, documentation and freight to your country.

Reference standards for Levofolinate

See every impurity, metabolite and related compound we list for this API.

Levofolinate standards

Typical uses

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Applications

Pharmaceutical Manufacturing and QC Research Labs and Universities

Specifications and identifiers

Specifications of Dihydro Folic Acid
Product name	Dihydro Folic Acid
Catalogue number	ZX-023087
CAS number	4033-27-6
IUPAC name	(2S)-2-[[4-[(2-amino-4-oxo-7,8-dihydro-3H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
Molecular formula	C₁₉H₂₁N₇O₆
Molar mass	443.4 g/mol
Exact mass	443.1553
Grade	Reference Standard
Physical form	Solid
XLogP3	-0.9
H-bond donors / acceptors	7 / 10
Topological polar surface area	208 Å²
HS code	38229090
InChIKey	OZRNSSUDZOLUSN-LBPRGKRZSA-N
SMILES	C1C(=NC2=C(N1)N=C(NC2=O)N)CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O
PubChem CID	135398604
Synonyms	7,8-Dihydrofolicacid, dihydrofolate, 7,8-Dihydrofolic acid, 7,8-Dihydropteroylglutamate, 7,8-Dihydropteroyl-L-glutamic acid, 7,8-Dihydro-L-folic acid, N-(7,8-dihydropteroyl)-L-glutamic acid, H2PteGlu, H2PteGlu1, (s)-2-(((9h-fluoren-9-yl)methoxy)carbonylamino)-3-phenylpropanoic acid

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

Irritant or harmful

Signal word Warning

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Dihydro Folic Acid
10 mg	Quoted on request
25 mg	Quoted on request
50 mg	Quoted on request
100 mg	Quoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Dihydro Folic Acid

Which CAS number identifies Dihydro Folic Acid?

Dihydro Folic Acid is registered under CAS 4033-27-6. You may also see it listed as 7,8-Dihydrofolicacid, dihydrofolate, 7,8-Dihydrofolic acid. Our catalogue number for this item is ZX-023087.

What are the formula and molar mass of Dihydro Folic Acid?

For Dihydro Folic Acid, its formula is C19H21N7O6 and its molar mass is 443.4 g/mol. The systematic (IUPAC) name is (2S)-2-[[4-[(2-amino-4-oxo-7,8-dihydro-3H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid. InChIKey OZRNSSUDZOLUSN-LBPRGKRZSA-N lets you match it in any structure database.

How is Dihydro Folic Acid used in pharmaceutical QC?

Dihydro Folic Acid is a characterised reference material linked to Levofolinate. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.

What grade and pack sizes are available for Dihydro Folic Acid?

This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.

Which documents come with Dihydro Folic Acid?

Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.

Can Zemixal ship Dihydro Folic Acid to my country?

Yes. Because Dihydro Folic Acid is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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