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Metabolites & Degradation Products

2-Hydroxy-2-(2,4,5-trifluorophenyl)acetic acid

Reference StandardAvailable on request

2-Hydroxy-2-(2,4,5-trifluorophenyl)acetic acid (CAS 375369-29-2) supplier Zemixal: C8H5F3O3, COA and SDS with every lot, worldwide shipping.

Pack sizes
2-Hydroxy-2-(2,4,5-trifluorophenyl)acetic acid chemical structure
CAS number375369-29-2
FormulaC8H5F3O3
Molar mass206.12 g/mol
Physical formSolid
HS code38229090
InChIKeyKGSNZRPLTBOIQG-UHFFFAOYSA-N
IUPAC name2-hydroxy-2-(2,4,5-trifluorophenyl)acetic acid

About 2-Hydroxy-2-(2,4,5-trifluorophenyl)acetic acid

Analytical teams working on Sitagliptin use 2-Hydroxy-2-(2,4,5-trifluorophenyl)acetic acid as a qualified comparison standard. Identity at a glance (Reference Standard): CAS 375369-29-2, formula C8H5F3O3 and molar mass 206.12 g/mol. It is handled as a solid.

Typical applications

  • Metabolite identification
  • Stability-indicating methods
  • Impurity profiling

Storage and safety notes

It carries the GHS signal word Warning (H302, H315, H319 and H335), so wear gloves and eye protection and work with good ventilation.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and custom quantities are quoted on request. You receive a certificate of analysis with characterisation data with each order. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.

Reference standards for Sitagliptin

See every impurity, metabolite and related compound we list for this API.

Sitagliptin standards

Typical uses

  • Metabolite identification
  • Stability-indicating methods
  • Impurity profiling

Applications

Pharmaceutical Manufacturing and QCResearch Labs and Universities

Specifications and identifiers

Specifications of 2-Hydroxy-2-(2,4,5-trifluorophenyl)acetic acid
Product name2-Hydroxy-2-(2,4,5-trifluorophenyl)acetic acid
Catalogue numberZX-036735
CAS number375369-29-2
IUPAC name2-hydroxy-2-(2,4,5-trifluorophenyl)acetic acid
Molecular formulaC8H5F3O3
Molar mass206.12 g/mol
Exact mass206.0191
GradeReference Standard
Physical formSolid
XLogP31.1
H-bond donors / acceptors2 / 6
Topological polar surface area57.5 Ų
HS code38229090
InChIKeyKGSNZRPLTBOIQG-UHFFFAOYSA-N
SMILESC1=C(C(=CC(=C1F)F)F)C(C(=O)O)O
PubChem CID44139266
Synonyms2,4,5-Trifluoromandelic acid

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS07 Irritant or harmful
Irritant or harmful

Signal word Warning

  • H302Harmful if swallowed
  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of 2-Hydroxy-2-(2,4,5-trifluorophenyl)acetic acid
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about 2-Hydroxy-2-(2,4,5-trifluorophenyl)acetic acid

Which CAS number identifies 2-Hydroxy-2-(2,4,5-trifluorophenyl)acetic acid?
2-Hydroxy-2-(2,4,5-trifluorophenyl)acetic acid is registered under CAS 375369-29-2. You may also see it listed as 2,4,5-Trifluoromandelic acid. Our catalogue number for this item is ZX-036735.
What are the formula and molar mass of 2-Hydroxy-2-(2,4,5-trifluorophenyl)acetic acid?
For 2-Hydroxy-2-(2,4,5-trifluorophenyl)acetic acid, its formula is C8H5F3O3 and its molar mass is 206.12 g/mol. The systematic (IUPAC) name is 2-hydroxy-2-(2,4,5-trifluorophenyl)acetic acid. InChIKey KGSNZRPLTBOIQG-UHFFFAOYSA-N lets you match it in any structure database.
How is 2-Hydroxy-2-(2,4,5-trifluorophenyl)acetic acid used in pharmaceutical QC?
2-Hydroxy-2-(2,4,5-trifluorophenyl)acetic acid is a characterised reference material linked to Sitagliptin. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for 2-Hydroxy-2-(2,4,5-trifluorophenyl)acetic acid?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with 2-Hydroxy-2-(2,4,5-trifluorophenyl)acetic acid?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship 2-Hydroxy-2-(2,4,5-trifluorophenyl)acetic acid to my country?
Yes. Because 2-Hydroxy-2-(2,4,5-trifluorophenyl)acetic acid is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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